Los Angeles Angels vs St. Louis Cardinals Prediction, 4/1/2025 MLB Picks, Best Bets & Odds
Game: Los Angeles Angels vs St. Louis Cardinals
Date: Tuesday, April 1, 2025
Location: Busch Stadium in St. Louis, MO
TV: FanDuel Sports Network Midwest
Odds/Point Spread: Los Angeles (+125) St. Louis (-145)
The St. Louis Cardinals (3-0) will compete against the Los Angeles Angels (2-1) at Busch Stadium on Tuesday. The moneyline on this game has the Angels at +125 and the Cardinals are at -145. The betting total comes in at 9. The pitchers expected to start will be Kyle Hendricks and Matthew Liberatore.


The Angels have hit 2 two-baggers as a unit and have hit 2 baseballs out of the stadium. Los Angeles owns a slugging percentage of .287 and have been called out on strikes 23 times, while being walked on 8 occasions. As a unit, the Los Angeles Angels are putting up 1.7 runs per game, which ranks them 29th in baseball. They have accumulated 5 runs batted in in addition to 19 hits over the course of the season, and their batting average is sitting at .202. They have earned 5 runs and have an OBP of .276.
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The Angels have an ERA of 3.46 on the campaign (15th in the league), and the staff has rung up 19 hitters. Angels pitchers have relinquished 4 long balls in addition to 10 total runs (10th in the league). They have walked 8 opposing players and their FIP is 4.09 as a team over the course of the season. Los Angeles has allowed 18 hits (6.2 per 9 innings) and also 10 earned runs. They have accumulated a K/BB ratio of 2.38 and their pitching staff sits with a WHIP of 1.00.
Angels bullpen pitchers have gone to the mound with runners on base 1 time and also have had 6 appearances in high leverage situations. The relievers have accumulated 2 holds on the campaign (17th in the league). The Angels bullpen have a save percentage of 100.0% and has stepped onto the mound in 4 save situations. They have earned 2 saves this season. The relievers have inherited 2 base runners this season with none of those players crossed the plate. The Angels have sent 8 relief pitchers to the mound on the season.
The Kansas City Royals have earned a total of 78 putouts on the year, in addition to 31 assists and 0 errors. Their fielding percentage is holding at 1.000 which has them sitting 3rd in baseball, and have accumulated 4 double plays. The Angels have converted 79.7% of baseballs in play into outs in their 234 innings, ranking them 4th in MLB.
Hendricks (97-81 career win-loss record) sits with a FIP of 3.63 and he has faced 6,518 opposing batters in the majors. He has allowed 1,501 base knocks (8.5 hits per nine innings) and has had 364 walks. His ERA is 3.69 (647 earned runs allowed) and his career WHIP is 1.180. Hendricks has thrown 1,580 innings and has accounted for 1,259 K's in his career.
The St. Louis Cardinals have recorded an OBP of .389 in addition to a team batting average of .306 on the campaign. They have struck out on 19 occasions (28th in baseball) and have accounted for 30 hits. St. Louis has tallied 5 long balls over the course of the season as well as 19 runs batted in. The Cardinals have a team slugging % of .520 and they score 6.33 runs per contest (4th in baseball). They have put up 6 two-baggers, while getting a free base 12 times as well as putting up 19 runs.
The Cardinals hold a team WHIP of 0.778 with a FIP of 2.74 as a team on the season. They currently have a strikeout to walk ratio of 6.30 (19 strikeouts against 5 walks). They are currently ranked 3rd in MLB as a pitching staff in total hits surrendered with 16. They have surrendered 2 long balls and they surrender 2.00 runs per 9 innings (4th in baseball). The St. Louis pitching staff have allowed 6 runs this season while holding a team ERA of 2.00 (6 earned runs yielded).
St. Louis has called on relief pitchers to enter the game in 2 save chances and they have walked away with 2 saves. They rank 9th in the league with a save rate of 100.0%, and they have dispatched 9 relievers to the hill this season. Their relievers have stepped onto the mound 4 times in high leverage situations and also on 1 occasion with runners on. St. Louis relievers have an inherited score rate of 50.0% out of their 2 inherited runners. With 8 save situations, the Cardinals have tallied 6 holds and 0 blown saves.
In their 243 innings on the field, the Cardinals have earned a defensive efficiency of 80.3% (3rd in pro baseball). The St. Louis Cardinals have turned 2 double plays and have a fielding percentage of .991 (12th in professional baseball). The Cardinals have recorded 33 assists, 1 error and have amassed 81 putouts this season.
Liberatore (8-12 career mark) has earned a 4.99 ERA while allowing 9.3 hits per 9 innings. His K/BB ratio is 2.11 and he has faced 794 hitters in his career. He has given up a total of 101 earned runs while earning a WHIP of 1.428 and a FIP of 4.9. During his pro baseball career, Liberatore has surrendered 189 hits while accumulating 150 K's in 182 innings pitched.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take Los Angeles (+125)
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Additional Resources:
St. Louis Cardinals - Twitter
Los Angeles Angels - Twitter