Miami Marlins vs San Diego Padres Prediction, 5/27/2025 MLB Picks, Best Bets & Odds
Game: Miami Marlins vs San Diego Padres
Date: Tuesday, May 27, 2025
Location: Petco Park in San Diego, CA
TV: Padres.TV
Odds/Point Spread: Miami (+125) San Diego (-145)
Petco Park is the site where the San Diego Padres (29-22) will attempt to beat the Miami Marlins (21-30) on Tuesday. The moneyline on this game has the Marlins at +125 and the Padres are sitting at -145. The total is set at 8.5. The expected starting pitchers will be Max Meyer and Stephen Kolek.


Miami has a slugging percentage of .388 and have been called out on strikes 426 times, while drawing a walk on 159 occasions. They have accounted for 201 runs batted in in addition to 436 hits on the campaign, while their average at the plate comes in at .250. The Marlins have accounted for 83 doubles as a team and have hit 47 baseballs out of the park. They have 210 runs and have an OBP of .316. As a team, the Miami Marlins are notching 4.1 runs per game, which has them at 19th in MLB.
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Their strikeout to walk ratio sits at 2.11 and their pitching staff has a team WHIP of 1.46. Marlins pitchers have surrendered 63 home runs and also 285 total runs (27th in the league). Miami has allowed 463 hits (9.2 per 9 innings) in addition to 267 earned runs. The Marlins have a team ERA of 5.31 so far this year (28th in MLB), and they have rung up 411 hitters. Their pitching staff has walked 195 batters and their FIP comes in at 4.50 as a team over the course of the season.
Marlins pitchers have stepped onto the hill with players on base 51 times as well as having 57 appearances in high leverage situations. The relievers have notched 25 holds this year (26th in MLB). The Marlins relief pitchers have a save rate of 52.9% and have stepped onto the mound in 42 save situations. They have compiled 9 saves for the season and have blown 8 out of their 17 save chances. The bullpen pitchers have inherited 75 runners this season with 36.0% of those runners crossed home plate. The Marlins have dispatched 170 relievers to the mound on the campaign.
The Los Angeles Dodgers have accumulated 1,358 putouts over the course of the season, as well as 449 assists and 25 errors. Their fielding rate is currently at .986 which has them sitting 15th in baseball, and have a total of 35 double plays. The Marlins have transformed 68.2% of balls in play into outs in their 4,074 innings on the field, ranking them 22nd in pro baseball.
Meyer (6-10 career mark) holds a FIP of 4.99 and he has gone up against 513 batters during his time in the major leagues. He has allowed 124 hits (9.4 hits per 9 innings) with 38 walks. His earned run average is 5.06 (67 earned runs allowed) and his WHIP is 1.360. Meyer has thrown 119 innings and has earned 115 punch outs in his career.
San Diego has compiled 48 home runs so far this year and 195 runs batted in. They have hit 75 two-baggers, while taking a walk 155 times and notching 213 runs. The San Diego Padres hold a team OBP of .318 as well as a team batting average of .253 this season. The Padres have a team SLG% of .390 and they are earning 4.18 runs per contest (17th in the league). They have struck out on 364 occasions (30th in baseball) and have a total of 430 base hits.
The Padres have a team WHIP of 1.202 and have a FIP of 3.86 as a team over the course of the season. They have earned a K/BB ratio of 9.00 (449 strikeouts vs 167 bases on balls). They have a ranking of 3rd in the league as a pitching staff in total hits relinquished with 374. They have allowed 53 dingers and they relinquish 3.92 runs per 9 innings (10th in baseball). The San Diego pitching staff have conceded 196 runs for the year while holding a team ERA of 3.52 (176 earned runs yielded).
San Diego relievers hold an inherited score percentage of 39.4% out of 71 inherited runners. Their relief pitchers have stepped onto the mound 65 times in high leverage situations and on 50 occasions with runners on. With 60 save situations, the Padres have earned 35 holds and also 6 blown saves. They sit at 3rd in the league holding a save rate of 75.0%, and they have sent 176 relief pitchers onto the field so far this year. San Diego has had relief pitchers enter the game in 24 save opportunities and they have walked away with 18 saves.
In 4,050 innings on the diamond, the Padres have accumulated a efficiency on defense of 71.5% (7th in pro baseball). The San Diego Padres have gotten 38 double plays and own a fielding percentage of .985 (20th in the majors). The Padres have racked up 382 assists, 27 errors and have a tally of 1,350 putouts this season.
So far in his career, Kolek has surrendered 83 hits while tallying 60 K's in 71 innings. He has surrendered 35 earned runs while holding a WHIP of 1.445 and being the owner of a FIP of 4.4. He has a strikeout to walk ratio of 3.00 and he has gone up against 315 opposing batters in his pro baseball career. Kolek (5-1 career mark) holds a 4.42 ERA and has conceded 10.5 hits per 9 innings.
Who will win tonight's MLB game against the spread or moneyline?
Tony Sink's Pick: Take San Diego (-145)
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Additional Resources:
San Diego Padres - Twitter
Miami Marlins - Twitter