Miami Marlins vs St. Louis Cardinals Prediction, 7/30/2025 MLB Picks, Best Bets & Odds

Game: Miami Marlins vs St. Louis Cardinals

Date: Wednesday, July 30, 2025

Location: Busch Stadium in St. Louis, MO

TV: FanDuel Sports Network Midwest

Odds/Point Spread: Miami (+132) St. Louis (-160)

Busch Stadium is where the St. Louis Cardinals (55-53) will try to defeat the Miami Marlins (50-55) on Wednesday. The moneyline on this matchup has Miami at +132 while St. Louis is opening at -160. The over/under comes in at 9. The pitchers expected to start will be Cal Quantrill and Miles Mikolas.

As a squad, the Miami Marlins are knocking in 4.3 runs/g, which has them at 20th in MLB. They have notched a total of 446 runs scored and have an OBP of .315. The Marlins have earned 178 two-baggers as a squad and have hit 97 balls out of the park. They have compiled 428 RBI's and 903 base knocks so far this year, and their average at the plate is .252. Miami has a slugging percentage of .393 and have been called out on strikes 829 times, while drawing a walk on 314 occasions.

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They have earned a strikeout to walk ratio of 2.51 and their pitching staff has a collective WHIP of 1.31. Marlins pitchers have allowed 111 home runs in addition to 500 runs in total (24th in the league). Miami has relinquished 895 base hits (8.6 per 9 innings) and also 461 earned runs. The Marlins have compiled a team earned run average of 4.44 this season (24th in baseball), and the staff has rung up 824 batters. They have walked 328 opposing players and their FIP comes in at 4.07 as a team so far this year.

Marlins pitchers have entered the contest with opponents on base 83 times in addition to having 114 appearances in high leverage situations. The relievers have racked up 58 holds on the season (19th in baseball). The Marlins relief pitchers have accumulated a save rate of 60.5% and have come into the game in 102 save situations. They have earned 26 saves on the season and have missed out on 17 of their 43 save opportunities. The bullpen pitchers have inherited 121 runners over the course of the season with 32.2% of them ended up crossing the plate. The Marlins have sent 330 relief pitchers to the hill so far this season.

The Marlins have turned 69.5% of balls hit into play into outs in their 8,409 innings on the diamond, which has them sitting at 18th in baseball. The Los Angeles Dodgers are sitting with 2,803 putouts this season, as well as 921 assists and 55 errors. Their fielding percentage is currently at .985 which puts them in 19th in baseball, and have 72 double plays.

Quantrill (46-42 career mark) is the owner of a FIP of 4.12 and he has gone up against 3,453 hitters in the majors. He has allowed 810 base knocks (9.0 hits per nine innings) and has 258 free passes. His ERA is 4.18 (377 earned runs allowed) and his WHIP is 1.317. Quantrill has taken the ball for 811 frames and has totaled 611 strikeouts so far in his career.

St. Louis has knocked in 105 home runs so far this year and 461 runs batted in. They have notched 195 doubles, while walking 337 times as well as recording 483 runs. The St. Louis Cardinals have compiled an OBP of .321 in addition to a batting average of .251 so far this season. The Cardinals have a team slugging percentage of .393 and they score 4.47 runs per contest (13th in MLB). They have struck out on 821 occasions (27th in the league) and are sitting with 915 base hits.

The Cardinals have a team WHIP of 1.289 and have a FIP of 3.82 as a pitching staff on the year. They are currently ranked 26th in baseball as a pitching staff in total hits surrendered with 943. The St. Louis pitching staff have surrendered 485 runs on the campaign while holding a team ERA of 4.19 (444 earned runs relinquished). Their K/BB ratio is 7.40 (788 strikeouts against 287 walks). They have allowed 102 home runs and they concede 4.57 runs per 9 innings (22nd in baseball).

St. Louis has had relievers step onto the hill in 40 save chances and they have earned 26 saves. They rank 13th in MLB with a save percentage of 65.0%, and they have sent 322 relievers to the hill this season. Their relievers have come in 106 times in high leverage situations in addition to 105 occasions with runners on. St. Louis relief pitchers have an inherited score percentage of 32.2% of 143 inherited base runners. Sitting with 106 save situations, the Cardinals have accumulated 63 holds in addition to 14 blown saves.

The St. Louis Cardinals have gotten 83 double plays and have a fielding rate of .989 (5th in baseball). The Cardinals have racked up 1,043 assists, 45 errors and have notched a total of 2,864 putouts on the season. In 8,592 innings on the field, the Cardinals hold a defensive efficiency of 69.3% (20th in the majors).

Mikolas (70-71 win-loss mark in his career) has earned a 4.22 earned run average while surrendering 9.2 hits per 9 innings. His strikeout to walk ratio is 3.73 and he has gone up against 4,985 hitters so far in his MLB career. He has given up a total of 562 ER's while earning a WHIP of 1.210 and being the owner of a FIP of 4.2. So far in his pro baseball career, Mikolas has conceded 1,218 base hits and he has 865 strikeouts in 1,198 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Miami (+132)

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