Milwaukee Brewers vs Chicago Cubs Prediction, 10/8/2025 MLB Picks, Best Bets & Odds

Game: Milwaukee Brewers vs Chicago Cubs

Date: Wednesday, October 8, 2025

Location: Wrigley Field in Chicago, IL

TV: TBS

Odds/Point Spread: Milwaukee (-132) Chicago (+110)

Wrigley Field is where the Chicago Cubs (92-70) will go up against the Milwaukee Brewers (97-65) on Wednesday in Game 3 of the NLDS. The Brewers lead the series 2-0. The moneyline on this contest has Milwaukee at -132 and Chicago is priced at +110. The total comes in at 7. The pitchers taking the mound are Quinn Priester and Jameson Taillon.

Milwaukee is slugging .403 and have struck out 1,266 times, while taking a walk on 564 occasions. They have recorded 750 RBI's and 1,423 hits so far this season, while their average at the plate comes in at .258. The Brewers have recorded 265 doubles as a team and have knocked 166 balls out of the park. They have notched a total of 806 runs scored and have an OBP of .332. As a team, the Milwaukee Brewers are scoring 5.0 runs per game, which ranks them 3rd in the league.

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The Brewers have an earned run average of 3.58 on the year (2nd in the league), and the staff has struck out 1,432 hitters. Brewers pitchers have conceded 168 long balls and 634 total runs (3rd in the league). They have walked 534 opposing players and their FIP comes in at 3.91 as a squad on the season. Milwaukee has given up 1,237 hits (7.7 per 9 innings) as well as 574 earned runs. They have earned a K/BB ratio of 2.68 and the pitching staff has a collective WHIP of 1.23.

Brewers pitchers have entered the game with runners on 145 times in addition to having 187 appearances in high leverage situations. The relief pitchers have 107 holds over the course of the season (4th in MLB). The Brewers bullpen have recorded a save percentage of 68.2% and have stepped onto the mound in 177 save situations. They have earned 45 saves on the campaign and have blown 21 out of their 66 chances to get a save. The relief pitchers have inherited 218 base runners this year with 31.7% of those players ended up crossing the plate. The Brewers have dispatched 550 relievers to the mound on the year.

The Brewers have turned 70.9% of balls hit into play into outs out of 12,978 innings on the diamond, which has them sitting 5th in the majors. The Miami Marlins have earned a total of 4,326 putouts on the year, as well as 1,297 assists and 76 errors. Their fielding percentage is at .987 which ranks 10th in pro baseball, and have accumulated 122 double plays.

Priester (19-12 career mark) holds a FIP of 4.39 while he has gone up against 1,108 batters in the majors. He has surrendered 259 hits (9.1 hits per 9 innings) with 91 walks. His ERA is 4.46 (127 earned runs allowed) and his career WHIP is 1.366. Priester has taken the ball for 256 innings and has accumulated 201 strikeouts during his MLB career.

Chicago has accounted for 223 home runs this season to go along with 771 RBIs. They have hit 267 doubles, while getting a free base 554 times as well as recording 793 runs. The Chicago Cubs have accounted for a team on-base percentage of .320 and a team batting average of .249 on the year. The Cubs hold a team slugging percentage of .430 and they have an average of 4.90 runs per outing (5th in the league). They have been rung up on 1,277 occasions (25th in the league) and are sitting with 1,371 base hits.

The Chicago pitching staff have relinquished 649 runs so far this year and come in with a team ERA of 3.79 (605 earned runs allowed). They have yielded 202 homers and they relinquish 4.07 runs per 9 innings (8th in baseball). The Cubs have a WHIP of 1.177 in addition to having a FIP of 4.16 as a team this year. They currently have a K/BB ratio of 7.90 (1,265 strikeouts vs 405 bases on balls). They are sitting at 10th in baseball as a staff in total hits allowed with 1,284.

Chicago relievers hold an inherited score rate of 33.8% out of their 142 inherited runners. Their bullpen pitchers have come in 158 times in high leverage situations in addition to 101 occasions with runners on base. Sitting with 177 save situations, the Cubs have earned 110 holds and 20 blown saves. They sit at 4th in the league with a save percentage of 68.8%, and they have dispatched 523 bullpen pitchers to the mound this year. Chicago has had bullpen pitchers step onto the hill in 64 save opportunities and they have recorded 44 saves.

The Chicago Cubs have turned 117 double plays and have a fielding percentage of .989 (4th in the majors). The Cubs have accrued 1,342 assists, 61 errors and have earned a total of 4,305 putouts for the year. In their 12,915 innings played, the Cubs have earned a defensive efficiency of 71.9% (2nd in baseball).

So far in his career, Taillon has given up 1,182 hits while accumulating 1,073 K's in 1,236 innings pitched. He has given up a total of 532 ER's while earning a WHIP of 1.194 and a FIP of 3.8. He has a K/BB ratio of 3.65 and he has faced 5,128 batters during his pro baseball career. Taillon (82-60 career win-loss record) has a 3.87 earned run average and has conceded 8.6 hits per nine innings.

Who will win tonight's MLB game against the spread or moneyline?

Parlay's Pundit's Pick: Take Chicago (+110) and under 9 runs

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