Minnesota Twins vs Cleveland Guardians Prediction, 4/30/2025 MLB Picks, Best Bets & Odds

Game: Minnesota Twins vs Cleveland Guardians

Date: Wednesday, April 30, 2025

Location: Progressive Field in Cleveland, OH

TV: CLEGuardians.TV

Odds/Point Spread: Minnesota (+126) Cleveland (-152)

The Cleveland Guardians (15-13) will try to defeat the Minnesota Twins (13-16) at Progressive Field on Wednesday. The line on this contest has Minnesota at +126 while Cleveland is sitting at -152. The betting total comes in at 9. The pitchers expected to start will be Pablo Lopez and Luis Ortiz.

As a squad, the Minnesota Twins are recording 4.0 runs per game, which ranks them 19th in baseball. They have a total of 117 runs while holding a team on-base percentage of .310. The Twins have hit 54 doubles as a squad and have hit 23 balls out of the park. They have accounted for 112 runs batted in and 223 hits this season, and their batting average is .234. Minnesota is slugging .371 and have struck out 233 times, while drawing a walk on 89 occasions.

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The Twins have compiled a team earned run average of 3.55 this year (10th in MLB), and the staff has struck out 250 batters. Twins pitchers have yielded 30 long balls and also 109 runs in total (9th in baseball). They have walked 74 players from the other team and their FIP is 3.69 as a team for the year. Minnesota has given up 229 base knocks (8.2 per 9 innings) as well as 99 earned runs. They have earned a K/BB ratio of 3.38 and the pitching staff has a collective WHIP of 1.21.

The Twins have sent 96 relief pitchers to the mound this year. The relief pitchers have inherited 35 runners this season with 37.1% of those runners ended up scoring. They have accumulated 3 saves on the season and have blown 5 out of their 8 chances to get a save. The Twins bullpen have a save percentage of 37.5% and have entered the game in 31 save situations. The relief pitchers have notched 22 holds so far this year (6th in MLB). Twins pitchers have entered the contest with runners on 22 times as well as having 23 appearances in high leverage situations.

The Twins have transformed 69.5% of balls hit into play into outs out of their 2,259 innings on the field, which has them ranked 19th in pro baseball. The Milwaukee Brewers have a total of 753 putouts for the season, as well as 191 assists and 18 errors. Their fielding percentage sits at .981 which is 24th in MLB, and have a total of 15 double plays.

Lopez has thrown 910 innings and is sitting with 941 punch outs during his career. His earned run average is 3.87 (391 earned runs allowed) and his WHIP is 1.180. He has conceded 839 hits (8.3 hits per nine innings) with 235 walks. Lopez (56-50 career win-loss mark) has earned a FIP of 3.81 while he has gone up against 3,772 hitters in the majors.

Cleveland has recorded 30 home runs so far this year as well as 102 RBIs. They have 37 two-baggers, while getting a free base 86 times as well as notching 108 runs. The Cleveland Guardians have recorded an on-base percentage of .306 as well as a batting average of .237 so far this season. The Guardians hold a team SLG% of .381 and they are earning 3.86 runs per game (21st in the league). They have been rung up on 218 instances (24th in MLB) and have 216 hits.

The Guardians hold a team WHIP of 1.455 and have a FIP of 4.44 as a squad so far this season. They are sitting at 23rd in MLB as a pitching staff in total hits given up with 249. The Cleveland pitching staff have conceded 136 runs this season while having a team ERA of 4.61 (126 earned runs surrendered). Their K/BB ratio comes in at 8.70 (237 strikeouts vs 109 walks). They have relinquished 36 HR's and they concede 4.98 runs per 9 innings (24th in the league).

Cleveland has had bullpen pitchers step onto the mound in 12 save opportunities and they have come away with 9 saves. They sit at 5th in baseball with a save percentage of 75.0%, and they have sent 98 relievers to the hill on the season. Their relievers have stepped onto the mound 24 times in high leverage situations and also on 24 occasions with runners on. Cleveland relievers have an inherited score percentage of 20.6% out of their 34 inherited runners. Sitting with 40 save situations, the Guardians have tallied 28 holds in addition to 3 blown saves.

The Cleveland Guardians have turned 25 double plays and have earned a fielding percentage of .981 (23rd in pro baseball). The Guardians have accrued 215 assists, 18 errors and have a total of 738 putouts so far this season. In 2,214 innings on the diamond, the Guardians are sitting with a defensive efficiency of 67.2% (26th in professional baseball).

Ortiz (14-16 career mark) has earned a 4.14 ERA and has allowed 8.3 hits per 9 innings. He has a K/BB ratio of 1.88 and he has faced 1,142 batters in his career. He has conceded a total of 121 earned runs while earning a WHIP of 1.352 and having a FIP of 4.1. During his career, Ortiz has surrendered 242 hits while he has earned 214 strikeouts in 263 innings.

Who will win tonight's MLB game against the spread or moneyline?

Parlay's Pundit's Pick: Take Cleveland (-152) and under 9 runs

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