Minnesota Twins vs Detroit Tigers Prediction, 8/4/2025 MLB Picks, Best Bets & Odds

Game: Minnesota Twins vs Detroit Tigers

Date: Monday, August 4, 2025

Location: Comerica Park in Detroit, MI

TV: FanDuel Sports Network Detroit

Odds/Point Spread: Minnesota (+220) Detroit (-275)

Comerica Park is where the Detroit Tigers (64-46) will meet the Minnesota Twins (51-57) on Monday. The odds on this game have the Twins at +220 and the Tigers are priced at -275. The total has been set at 9. The starting pitchers are Zebby Matthews and Casey Mize.

The Twins have accounted for 168 two-baggers as a team and have smacked 125 baseballs out of the stadium. Minnesota owns a slugging percentage of .399 and have been called out on strikes 884 times, while taking a walk on 322 occasions. As a unit, the Minnesota Twins are compiling 4.2 runs per game, which ranks them 22nd in baseball. They have amassed 432 RBI's in addition to 870 hits this year, and their batting average sits at .241. They have accumulated 451 runs scored while holding a team OBP of .313.

Get all of our MLB Betting Picks

The Twins have an ERA of 4.29 so far this year (23rd in baseball), and the staff has struck out 919 batters. Twins pitchers have allowed 121 home runs and 484 runs (20th in MLB). Their pitching staff has walked 282 batters and their FIP sits at 3.86 as a squad for the season. Minnesota has surrendered 923 hits (8.8 per 9 innings) in addition to 452 earned runs. They have accumulated a K/BB ratio of 3.26 and their pitching staff has a collective WHIP of 1.27.

The Twins relief pitchers have earned a save percentage of 57.1% and have entered the game in 110 save situations. The bullpen pitchers have inherited 110 runners on the campaign with 36.4% of those players ended up scoring. Twins relief pitchers have gone to the mound with players on base 77 times as well as having 130 appearances in high leverage situations. The Twins have sent 373 relief pitchers to the hill so far this year. The relievers have recorded 73 holds over the course of the season (6th in the league). They have earned 20 saves so far this season and have blown 15 of 35 chances to save the game.

The Twins have turned 68.7% of balls hit into play into outs out of their 8,529 innings, which has them ranked 26th in the majors. The Milwaukee Brewers are sitting with 2,843 putouts over the course of the season, in addition to 797 assists and 52 errors. Their fielding rate is at .986 which has them sitting 16th in baseball, and have a total of 55 double plays.

Matthews has thrown 70 innings and has racked up 85 punch outs so far in his MLB career. His ERA is 6.27 (49 earned runs allowed) and his career WHIP is 1.550. He has given up 89 base knocks (11.4 hits per 9 innings) and has had 20 walks. Matthews (3-7 career record) has earned a FIP of 6.18 while going up against 322 batters during his time in the majors.

Detroit is sitting with 138 home runs this year and 512 RBIs. They have recorded 174 doubles, while taking a walk 342 times and earning 532 runs. The Detroit Tigers have recorded a team OBP of .319 in addition to a batting average of .250 for the season. The Tigers hold a team slugging % of .421 and they score 4.84 runs per outing (6th in baseball). They have struck out on 969 occasions (5th in baseball) and have tallied 927 base hits.

The Tigers are sitting with a team WHIP of 1.235 and are the owners of a FIP of 3.82 as a staff so far this season. They come in at 14th in baseball as a staff in total hits given up with 888. The Detroit pitching staff have conceded 451 runs for the year while holding a team ERA of 3.76 (407 earned runs relinquished). They have earned a strikeout to walk ratio of 8.70 (939 strikeouts vs 316 bases on balls). They have given up 116 dingers and they relinquish 4.16 runs per 9 innings (10th in baseball).

Detroit has had bullpen pitchers step onto the mound in 42 save chances and they have earned 28 saves. They are currently ranked 9th in baseball with a save percentage of 66.7%, and they have dispatched 342 relief pitchers onto the field for the year. Their relievers have come in 89 times in high leverage situations and on 121 occasions with base runners. Detroit relievers have an inherited score percentage of 26.3% of 167 inherited base runners. Sitting with 97 save situations, the Tigers have tallied 52 holds in addition to 14 blown saves.

Out of their 8,778 innings played, the Tigers have earned a defensive efficiency of 69.8% (14th in professional baseball). The Detroit Tigers have turned 85 double plays and have notched a fielding percentage of .986 (14th in pro baseball). The Tigers have accrued 927 assists, 54 errors and are sitting with 2,926 putouts over the course of the season.

In his career, Mize has given up 392 hits while earning 310 strikeouts in 385 innings pitched. He has conceded 177 earned runs while earning a WHIP of 1.306 and being the owner of a FIP of 4.1. He has a strikeout to walk ratio of 2.79 and he has gone up against 1,646 batters during his career. Mize (18-23 mark in his career) holds a 4.14 earned run average while giving up 9.2 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Minnesota (+220)

Get $60 worth of FREE premium member picks. No Obligation. No Salesman. No Credit Card. Fast Sign up with Instant Access Click Here