Minnesota Twins vs Kansas City Royals Prediction, 9/5/2025 MLB Picks, Best Bets & Odds

Game: Minnesota Twins vs Kansas City Royals

Date: Friday, September 5, 2025

Location: Kauffman Stadium in Kansas City, MO

TV: FanDuel Sports Network Kansas City

Odds/Point Spread: Minnesota (+150) Kansas City (-182)

The Minnesota Twins (62-77) are on their way to Kauffman Stadium on Friday where they will try to beat the Kansas City Royals (70-69). The moneyline on this contest has Minnesota at +150 and Kansas City is priced at -182. The total has been set at 8. The pitchers who are expected to start will be Joe Ryan and Michael Wacha.

As a squad, the Minnesota Twins are scoring 4.2 runs per contest, which ranks them 25th in the league. They are sitting with 584 runs scored and hold an on-base percentage of .311. The Twins have hit 213 doubles as a team and have knocked 163 balls out of the park. They have 555 RBI's in addition to 1,109 base knocks this year, while their average at the plate comes in at .238. Minnesota has a slugging rate of .397 and have been called out on strikes 1,151 times, while drawing a walk on 427 occasions.

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They have a K/BB ratio of 2.98 and their pitching staff holds a WHIP of 1.32. Twins pitchers have conceded 169 long balls and 658 total runs (23rd in baseball). Minnesota has given up 1,223 base hits (9.0 per 9 innings) and 613 earned runs. The Twins have compiled a team earned run average of 4.51 for the year (24th in the league), and the staff has struck out 1,167 batters. Their pitching staff has walked 392 hitters and their FIP is 4.13 as a unit for the year.

The Twins have sent 472 relief pitchers to the mound so far this season. The relief pitchers have inherited 148 runners for the season with 37.8% of those players crossed home plate. They have tallied 26 saves so far this year and have blown 22 out of their 48 save opportunities. The Twins bullpen have a save percentage of 54.2% and have come into the game in 134 save situations. The bullpen have racked up 84 holds this season (10th in baseball). Twins relief pitchers have entered the game with players on base 103 times and also have had 159 appearances in high leverage situations.

The Twins have turned 68.4% of baseballs in play into outs out of their 11,016 innings, ranking them 27th in the majors. The Milwaukee Brewers have a total of 3,672 putouts on the year, in addition to 1,034 assists and 68 errors. Their fielding rate is holding steady at .986 which is 16th in pro baseball, and have a total of 85 double plays.

Ryan (46-33 record in his career) holds a FIP of 3.66 while he has gone up against 2,528 opposing batters during his time in the majors. He has conceded 516 base knocks (7.4 hits per nine innings) and has had 139 walks. His ERA is 3.71 (258 ER's allowed) and he has a WHIP of 1.048. Ryan has pitched in 625 innings and has earned 699 punch outs thus far in his career.

The Royals hold a team SLG% of .392 and they average 3.83 runs per outing (28th in baseball). They have put up 244 doubles, while taking a walk 365 times and scoring 533 runs. Kansas City has compiled 132 home runs this season and 523 runs batted in. They have struck out on 945 occasions (30th in the league) and have a total of 1,137 hits. The Kansas City Royals have compiled an OBP of .306 in addition to a batting average of .245 so far this year.

The Kansas City pitching staff have given up 541 runs so far this year while having an ERA of 3.66 (502 earned runs surrendered). They have given up 142 long balls and they concede 3.94 runs per 9 innings (2nd in MLB). The Royals are sitting with a team WHIP of 1.244 and have a FIP of 3.97 as a staff so far this season. Their K/BB ratio comes in at 7.90 (1,086 strikeouts against 409 free passes). They come in at 10th in the league as a staff in total hits given up with 1,128.

Kansas City relief pitchers have an inherited score percentage of 27.9% of 190 inherited base runners. Their relief pitchers have taken the field 151 times in high leverage situations and also on 139 occasions with runners on base. Sitting with 133 save situations, the Royals have earned 73 holds and also 18 blown saves. They are ranked 4th in baseball with a save rate of 69.5%, and they have sent 466 relievers to the mound over the course of the season. Kansas City has called on bullpen pitchers to take the mound in 59 save opportunities and they have converted 41 saves.

The Kansas City Royals have turned 107 double plays and have a fielding rate of .989 (4th in pro baseball). The Royals have accrued 1,228 assists, 56 errors and have 3,708 putouts during this campaign. In 11,124 innings on the diamond, the Royals have a defensive efficiency of 70.8% (7th in baseball).

So far in his pro baseball career, Wacha has allowed 1,548 base hits while he has accumulated 1,402 strikeouts in 1,607 innings pitched. He has allowed a total of 689 earned runs while earning a WHIP of 1.272 and being the owner of a FIP of 3.8. His K/BB ratio is 2.82 and he has faced 6,760 hitters in his MLB career. Wacha (109-73 career win-loss mark) has earned a 3.86 ERA while allowing 8.7 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Minnesota (+150)

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