Minnesota Twins vs Milwaukee Brewers Prediction, 5/16/2025 MLB Picks, Best Bets & Odds
Game: Minnesota Twins vs Milwaukee Brewers
Date: Friday, May 16, 2025
Location: American Family Field in Milwaukee, WI
TV: FanDuel Sports Network Wisconsin
Odds/Point Spread: Minnesota (-275) Milwaukee (+220)
The Milwaukee Brewers (21-23) will play the Minnesota Twins (23-20) at American Family Field on Friday. The odds on this game have Minnesota at -275 and Milwaukee is coming in at +220. The total comes in at 8.5. The starting pitchers will be Joe Ryan and Chad Patrick.


The Twins have hit 70 doubles as a unit and have knocked 40 baseballs out of the park. Minnesota owns a slugging percentage of .380 and have struck out 354 times, while drawing a walk on 125 occasions. As a team, the Minnesota Twins are putting up 4.1 runs per game, which puts them at 17th in the league. They have tallied 170 RBI's as well as 341 hits for the season, and their average at the plate comes in at .239. They have accounted for 178 runs scored and have an on-base percentage of .310.
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The Twins are sitting with a team earned run average of 3.38 on the year (6th in baseball), and the staff has rung up 382 batters. Twins pitchers have conceded 43 long balls in addition to 154 runs in total (5th in MLB). They have walked 107 players from the other team and their FIP is 3.56 as a unit over the course of the season. Minnesota has given up 332 hits (8.0 per 9 innings) in addition to 141 earned runs. Their strikeout to walk ratio is 3.57 and their pitching staff sits with a WHIP of 1.17.
The Twins bullpen have recorded a save percentage of 61.1% and have stepped onto the mound in 56 save situations. The relief pitchers have inherited 47 runners for the season with 34.0% of those runners crossed home plate. Twins relief pitchers have entered the contest with runners on 33 times as well as having 56 appearances in high leverage situations. The Twins have sent 149 relief pitchers to the hill so far this year. The bullpen have tallied 36 holds over the course of the season (2nd in baseball). They have recorded 11 saves so far this season and have not converted 7 of their 18 save opportunities.
The Twins have converted 69.8% of baseballs in play into outs in their 3,378 innings on the field, which has them ranked 15th in baseball. The Milwaukee Brewers are sitting with 1,126 putouts this season, in addition to 301 assists and 26 errors. Their fielding rate is holding at .982 which has them sitting 23rd in MLB, and have accumulated 23 double plays.
Ryan (36-28 win-loss mark in his career) has a FIP of 3.76 while he has gone up against 2,092 hitters in the major leagues. He has allowed 429 hits (7.5 hits per nine innings) and has 114 walks. His ERA is 3.82 (219 earned runs allowed) and his WHIP is 1.052. Ryan has thrown 516 innings and has racked up 579 K's during his pro baseball career.
Milwaukee has a total of 37 long balls this year to go along with 174 runs batted in. They have 58 doubles, while walking 149 times and scoring 193 runs. The Milwaukee Brewers are sitting with a team OBP of .310 and a batting average of .233 on the season. The Brewers have a team slugging percentage of .355 and they are earning 4.39 runs per contest (15th in the league). They have been called out on strikes on 353 instances (18th in the league) and have accounted for 339 hits.
The Brewers are sitting with a team WHIP of 1.326 in addition to having a FIP of 4.41 as a squad for the year. They come in at 12th in baseball as a pitching staff in total hits given up with 338. The Milwaukee pitching staff have surrendered 193 runs this year while holding an ERA of 4.16 (177 earned runs conceded). Their K/BB ratio is 8.10 (346 strikeouts vs 170 bases on balls). They have allowed 49 home runs and they allow 4.53 runs per 9 innings (21st in the league).
With 40 save situations, the Brewers have recorded 28 holds in addition to 4 blown saves. Milwaukee has called on bullpen pitchers to enter the game in 11 save opportunities and they have converted 7 saves. Their relief pitchers have stepped onto the mound 46 times in high leverage situations and on 42 occasions with runners on. Milwaukee relievers have an inherited score rate of 37.1% of 70 inherited runners. They are currently ranked 15th in MLB with a save rate of 63.6%, and they have sent 160 bullpen pitchers onto the diamond over the course of the season.
The Milwaukee Brewers have turned 33 double plays and own a fielding percentage of .982 (24th in pro baseball). The Brewers have accrued 336 assists, 28 errors and have amassed 1,151 putouts over the course of the season. Out of their 3,453 innings on the field, the Brewers have earned a efficiency on defense of 71.1% (11th in baseball).
In his pro baseball career, Patrick has surrendered 39 hits while tallying 36 K's in 42 innings pitched. He has surrendered a total of 15 earned runs while earning a WHIP of 1.259 and a FIP of 3.2. He has a K/BB ratio of 2.57 and he has gone up against 175 hitters during his pro baseball career. Patrick (2-3 record in his career) has a 3.21 earned run average and has allowed 8.3 hits per 9 innings.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take Milwaukee (+220)
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Additional Resources:
Milwaukee Brewers - Twitter
Minnesota Twins - Twitter