New York Mets vs Washington Nationals Prediction, 8/21/2025 MLB Picks, Best Bets & Odds

Game: New York Mets vs Washington Nationals

Date: Thursday, August 21, 2025

Location: Nationals Park in Washington, D.C.

TV: MASN

Odds/Point Spread: New York (-275) Washington (+220)

Nationals Park is where the Washington Nationals (50-75) will try to defeat the New York Mets (67-58) on Thursday. The moneyline on this matchup has New York at -275 and Washington is coming in at +220. The betting total comes in at 8. The pitchers who are expected to start are Sean Manaea and MacKenzie Gore.

New York is slugging .415 and have been called out on strikes 1,001 times, while being walked on 426 occasions. They have accounted for 539 runs batted in as well as 1,008 hits on the campaign, and their average at the plate sits at .244. The Mets have accrued 199 doubles as a unit and have hit 160 balls out of the stadium. They have accumulated 554 runs while holding a team on-base percentage of .321. As a squad, the New York Mets are scoring 4.5 runs per game, which is 13th in MLB.

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The Mets have an earned run average of 3.78 for the season (7th in MLB), and their staff has struck out 1,059 hitters. Mets pitchers have surrendered 115 home runs and 518 runs (10th in the league). Their pitching staff has walked 446 opposing hitters and their FIP is 3.93 as a squad so far this year. New York has allowed 1,004 base knocks (8.2 per 9 innings) in addition to 462 earned runs. They have accrued a K/BB ratio of 2.37 and their pitching staff has recorded a WHIP of 1.32.

Mets relief pitchers have entered the contest with runners on 133 times in addition to having 155 appearances in high leverage situations. The bullpen have earned 80 holds so far this season (7th in MLB). The Mets relief pitchers have accumulated a save rate of 62.1% and have stepped onto the mound in 138 save situations. They have earned 36 saves on the season and have blown 22 of 58 save chances. The relief pitchers have inherited 197 runners this season and 34.5% of them ended up scoring. The Mets have sent 408 relief pitchers to the hill for the year.

The Mets have converted 69.5% of balls hit into play into outs out of 9,900 innings on the diamond, which has them sitting at 18th in professional baseball. The Minnesota Twins have a tally of 3,300 putouts this year, as well as 1,118 assists and 59 errors. Their fielding rate is holding steady at .987 which is 12th in MLB, and they have turned 91 double plays.

Manaea has taken the mound for 1,216 frames and has racked up 1,146 K's thus far in his career. His earned run average is 4.03 (544 earned runs allowed) and he has a WHIP of 1.201. He has given up 1,118 hits (8.3 hits per 9 innings) and has 342 walks. Manaea (78-63 career mark) has a FIP of 3.97 while he has gone up against 5,070 opposing batters during his time in the majors.

Washington has recorded 118 home runs this season as well as 512 RBIs. They have recorded 206 two-baggers, while walking 357 times and putting up 531 runs. The Washington Nationals have accounted for an OBP of .309 in addition to a team batting average of .244 so far this season. The Nationals hold a team SLG% of .388 and they are recording 4.28 runs per contest (20th in the league). They have been called out on strikes on 970 occasions (26th in the league) and have recorded 1,018 hits.

The Nationals are sitting with a team WHIP of 1.442 in addition to having a FIP of 4.57 as a squad for the season. They come in at 29th in baseball as a pitching staff in total hits given up with 1,153. The Washington pitching staff have given up 682 runs on the season while having a team ERA of 5.33 (645 earned runs relinquished). They currently have a K/BB ratio of 7.80 (942 strikeouts against 418 free passes). They have relinquished 153 dingers and they allow 5.64 runs per 9 innings (29th in MLB).

Sitting with 89 save situations, the Nationals have earned 49 holds and also 15 blown saves. Washington has had bullpen pitchers take the mound in 39 save opportunities and they have earned 24 saves. Their relievers have stepped onto the mound 95 times in high leverage situations in addition to 128 occasions with base runners. Washington relief pitchers hold an inherited score percentage of 40.6% out of their 217 inherited base runners. They are currently ranked 18th in the league holding a save percentage of 61.5%, and they have dispatched 437 bullpen pitchers onto the field on the campaign.

In 9,804 innings played, the Nationals have a defensive efficiency of 67.7% (29th in MLB). The Washington Nationals have turned 98 double plays and hold a fielding percentage of .985 (20th in baseball). The Nationals have 1,064 assists, 68 errors and have a tally of 3,268 putouts for the year.

Gore (26-38 record in his career) has a 4.16 ERA while giving up 8.9 hits per nine innings. His K/BB ratio is 2.74 and he has gone up against 2,205 hitters in his pro baseball career. He has given up 236 ER's while holding a WHIP of 1.396 and having a FIP of 4.1. In his MLB career, Gore has allowed 504 base knocks while he has accumulated 569 K's in 510 innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Washington (+220)

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