New York Yankees vs Baltimore Orioles Prediction, 9/19/2025 MLB Picks, Best Bets & Odds

Game: New York Yankees vs Baltimore Orioles

Date: Friday, September 19, 2025

Location: Oriole Park at Camden Yards in Baltimore, MD

TV: MASN

Odds/Point Spread: New York (-130) Baltimore (+110)

Oriole Park at Camden Yards is where the Baltimore Orioles (72-80) will take on the New York Yankees (85-67) on Friday. The moneyline on this contest has the Yankees at -130 and the Orioles are priced at +110. The betting total comes in at 8.5. The men taking the mound will be Will Warren and Trevor Rogers.

The Yankees have tallied 243 two-baggers as a team and have hit 258 balls out of the park. New York has a slugging percentage of .455 and have struck out 1,359 times, while being walked on 589 occasions. As a team, the New York Yankees are scoring 5.2 runs per game, which is 1st in the league. They have accumulated 766 RBI's in addition to 1,287 base knocks on the campaign, and their batting average comes in at .250. They have notched a total of 794 runs and have an on-base percentage of .330.

Get all of our MLB Picks Today

The Yankees are sitting with a team ERA of 4.05 so far this season (18th in the league), and their staff has rung up 1,343 hitters. Yankees pitchers have allowed 166 home runs and also 666 runs (16th in baseball). They have walked 528 players from the other team and their FIP comes in at 4.05 as a squad over the course of the season. New York has allowed 1,189 hits (7.9 per 9 innings) in addition to 608 earned runs. They have a strikeout to walk ratio of 2.54 and the pitching staff has earned a collective WHIP of 1.27.

The Yankees have dispatched 502 relievers to the mound this year. The bullpen pitchers have inherited 245 base runners so far this season and 28.2% of those runners ended up crossing the plate. They have compiled 41 saves on the campaign and have blown 21 of their 62 save opportunities. The Yankees relief pitchers have recorded a save rate of 66.1% and have stepped onto the mound in 159 save situations. The relievers are sitting with 95 holds on the year (7th in MLB). Yankees pitchers have come into the game with opponents on base 160 times as well as having 156 appearances in high leverage situations.

The Yankees have converted 70.3% of balls hit into play into outs out of their 12,147 innings on the field, which has them ranked 12th in the majors. The New York Mets have accumulated 4,049 putouts at this point in the season, in addition to 1,316 assists and 88 errors. Their fielding rate sits at .984 which ranks 24th in professional baseball, and have earned 104 double plays.

Warren has taken the mound for 174 frames and has earned 189 strikeouts so far in his pro baseball career. His ERA is 5.22 (101 ER's allowed) and he has a WHIP of 1.452. He has allowed 181 base knocks (9.4 hits per 9 innings) with 72 free passes. Warren (8-10 career win-loss mark) sits with a FIP of 5.14 and he has gone up against 776 opposing hitters in the major leagues.

The Baltimore Orioles have accumulated an OBP of .307 and a team batting average of .239 on the season. They have struck out on 1,354 occasions (4th in baseball) and are sitting with 1,221 hits. Baltimore has recorded 180 HRs for the season to go along with 617 runs batted in. The Orioles hold a slugging percentage of .400 and they are recording 4.28 runs per game (19th in baseball). They have put up 243 doubles, while getting a free base 449 times as well as recording 650 runs.

The Orioles have a team WHIP of 1.367 and are the owners of a FIP of 4.42 as a pitching staff on the season. Their K/BB ratio is 8.40 (1,253 strikeouts vs 488 free passes). They rank 27th in baseball as a pitching staff in total hits relinquished with 1,350. They have yielded 202 dingers and they give up 4.94 runs per 9 innings (24th in baseball). The Baltimore pitching staff have relinquished 738 runs on the year while holding an ERA of 4.59 (686 earned runs conceded).

Baltimore relief pitchers have an inherited score percentage of 26.3% out of their 205 inherited runners. Their relief pitchers have stepped onto the mound 163 times in high leverage situations and on 147 occasions with runners on base. Sitting with 164 save situations, the Orioles have compiled 103 holds and also 20 blown saves. They are ranked 10th in MLB holding a save rate of 64.9%, and they have sent 508 relievers to the hill so far this season. Baltimore has had bullpen pitchers enter the game in 57 save chances and they have walked away with 37 saves.

Out of their 12,102 innings on the diamond, the Orioles are sitting with a defensive efficiency of 68.5% (26th in baseball). The Baltimore Orioles have gotten 113 double plays and have accounted for a fielding rate of .985 (19th in professional baseball). The Orioles have 1,336 assists, 83 errors and are sitting with 4,034 putouts for the year.

In his career, Rogers has surrendered 477 hits while he has totaled 511 strikeouts in 510 frames. Rogers (23-36 career record) is the owner of a 3.79 ERA and has given up 8.4 hits per 9 innings. He has conceded a total of 215 ER's while holding a WHIP of 1.307 and a FIP of 3.7. He has a K/BB ratio of 2.69 and he has gone up against 2,185 hitters during his pro baseball career.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Baltimore (+110)

Get $60 worth of FREE premium member picks. No Obligation. No Salesman. No Credit Card. Fast Sign up with Instant Access Click Here