Philadelphia Phillies vs Houston Astros Prediction, 6/25/2025 MLB Picks, Best Bets & Odds

Game: Philadelphia Phillies vs Houston Astros

Date: Wednesday, June 25, 2025

Location: Daikin Park in Houston, TX

TV: Space City Home Network

Odds/Point Spread: Philadelphia (-196) Houston (+162)

Daikin Park is where the Houston Astros (45-33) will compete against the Philadelphia Phillies (47-31) on Wednesday. The moneyline on this game has Philadelphia at -196 and Houston opens at +162. The over/under has been set at 9. The starting pitchers are Zack Wheeler and Colton Gordon.

Philadelphia is slugging .407 and have been rung up 607 times, while drawing a walk on 274 occasions. They have 352 RBI's in addition to 684 base knocks over the course of the season, while their average at the plate is at .258. The Phillies have recorded 125 two-baggers as a unit and have hit 83 baseballs out of the park. They have accumulated 369 runs scored while holding a team OBP of .332. As a team, the Philadelphia Phillies are recording 4.7 runs per contest, which has them sitting at 7th in MLB.

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Their strikeout to walk ratio is 3.13 and their pitching staff has a collective WHIP of 1.28. Phillies pitchers have surrendered 85 home runs in addition to 328 total runs (15th in baseball). Philadelphia has allowed 663 base knocks (8.5 per 9 innings) and 302 earned runs. The Phillies are sitting with a team earned run average of 3.89 so far this year (16th in baseball), and the staff has rung up 717 batters. They have walked 229 opposing players and their FIP sits at 3.68 as a squad for the season.

The Phillies relief pitchers have earned a save percentage of 60.0% and have entered the game in 78 save situations. The relief pitchers have inherited 73 base runners so far this season and 41.1% of them crossed the plate. Phillies relief pitchers have stepped onto the hill with runners on 52 times and also have had 87 appearances in high leverage situations. The Phillies have dispatched 246 relief pitchers to the mound on the year. The relief pitchers have racked up 37 holds on the campaign (27th in the league). They have 24 saves so far this season and have not converted 16 of their 40 save chances.

The Phillies have turned 68.6% of balls hit into play into outs in their 6,291 innings on the field, which has them sitting at 22nd in pro baseball. The Philadelphia Phillies have amassed 2,097 putouts so far this season, in addition to 682 assists and 30 errors. Their fielding rate is at .989 which is 4th in pro baseball, and have 50 double plays.

Wheeler has taken the mound for 1,671 frames and has racked up 1,743 punch outs so far in his pro baseball career. Wheeler (110-72 mark in his career) is the owner of a FIP of 3.25 and he has faced 6,860 batters in the major leagues. His earned run average is 3.30 (612 earned runs allowed) and his WHIP is 1.143. He has surrendered 1,431 base hits (7.7 hits per nine innings) and has 479 walks.

The Astros have a team SLG% of .402 and they average 4.27 runs per game (16th in MLB). They have 113 doubles, while getting a free base 229 times as well as scoring 333 runs. Houston is sitting with 84 HRs this year to go along with 317 RBIs. They have been rung up on 606 occasions (25th in the league) and have tallied 674 hits. The Houston Astros have tallied a team on-base percentage of .323 in addition to a batting average of .257 so far this year.

The Houston pitching staff have conceded 287 runs so far this season while having a team ERA of 3.53 (270 earned runs yielded). They have given up 84 homers and they give up 3.75 runs per 9 innings (5th in baseball). The Astros have a team WHIP of 1.158 with a FIP of 3.59 as a unit this year. Their K/BB ratio comes in at 10.00 (768 strikeouts vs 236 free passes). They rank 1st in baseball as a pitching staff in total hits surrendered with 562.

Houston has called on relievers to step onto the mound in 30 save opportunities and they have converted 22 saves. They rank 5th in the league holding a save rate of 73.3%, and they have sent 241 relievers to the hill for the year. Their relief pitchers have come in 77 times in high leverage situations and on 58 occasions with runners on. Houston relievers have an inherited score percentage of 28.2% out of 85 inherited base runners. With 78 save situations, the Astros have recorded 48 holds and also 8 blown saves.

The Houston Astros have turned 48 double plays and have notched a fielding percentage of .987 (14th in baseball). The Astros have racked up 586 assists, 36 errors and have amassed 2,069 putouts this season. Out of their 6,207 innings on the field, the Astros have a defensive efficiency of 71.0% (8th in pro baseball).

Gordon (2-1 career record) has earned a 4.60 ERA while conceding 11.3 hits per nine innings. He has a K/BB ratio of 6.80 and he has gone up against 154 batters during his MLB career. He has surrendered a total of 18 ER's while earning a WHIP of 1.392 and a FIP of 4.5. In his career, Gordon has allowed 44 hits while accumulating 34 punch outs in 35 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Houston (+162)

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