Pittsburgh Pirates vs Washington Nationals Prediction, 9/14/2025 MLB Picks, Best Bets & Odds

Game: Pittsburgh Pirates vs Washington Nationals

Date: Sunday, September 14, 2025

Location: Nationals Park in Washington, D.C.

TV: MASN

Odds/Point Spread: Pittsburgh (-132) Washington (+110)

The Washington Nationals (60-86) host the Pittsburgh Pirates (64-83) at Nationals Park on Sunday. The odds on this game have the Pirates at -132 and the Nationals are priced at +110. The over/under is 8.5. The pitchers expected to start will be Mike Burrows and Cade Cavalli.

The Pirates have hit 220 two-baggers as a squad and have hit 105 balls out of the stadium. Pittsburgh has a slugging percentage of .349 and have struck out 1,288 times, while being walked on 481 occasions. As a unit, the Pittsburgh Pirates are scoring 3.6 runs per game, which is 30th in MLB. They have amassed 507 RBI's as well as 1,127 base knocks this season, and their team batting average sits at .232. They have earned a total of 527 runs scored while holding a team on-base percentage of .305.

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The Pirates have a team ERA of 3.87 for the year (11th in baseball), and the staff has rung up 1,173 hitters. Pirates pitchers have given up 138 long balls in addition to 599 runs in total (7th in the league). Their pitching staff has walked 432 opposing hitters and their FIP comes in at 3.88 as a team on the campaign. Pittsburgh has given up 1,159 base hits (8.0 per 9 innings) and also 558 earned runs. Their K/BB ratio is 2.72 and the pitching staff has a collective WHIP of 1.23.

The Pirates relievers have accumulated a save percentage of 58.9% and have come into the game in 123 save situations. The relievers have inherited 197 runners this year and 36.0% of them crossed home plate. Pirates relief pitchers have come into the game with runners on base 129 times as well as having 143 appearances in high leverage situations. The Pirates have sent 460 relievers to the mound on the campaign. The relief pitchers have racked up 65 holds for the year (26th in the league). They have accumulated 33 saves for the season and have blown 23 of 56 save chances.

The Pittsburgh Pirates have earned 3,893 putouts over the course of the season, as well as 1,221 assists and 70 errors. Their fielding percentage is holding steady at .986 which is 13th in MLB, and they have turned 108 double plays. The Pirates have turned 70.6% of balls hit into play into outs in their 11,679 innings on the diamond, which has them ranked 9th in MLB.

Burrows has thrown 88 innings and has earned 90 punch outs in his career. His ERA is 3.98 (39 earned runs allowed) and he has a WHIP of 1.257. He has given up 78 hits (8.0 hits per 9 innings) and has had 33 free passes. Burrows (3-4 career mark) holds a FIP of 3.92 while he has gone up against 374 batters during his time in the majors.

The Nationals hold a team slugging percentage of .390 and they have an average of 4.29 runs per contest (21st in the league). They have hit 240 doubles, while walking 410 times as well as putting up 626 runs. Washington has accounted for 140 HRs over the course of the season and 603 runs batted in. They have been called out on strikes on 1,183 occasions (23rd in the league) and have earned a total of 1,197 hits. The Washington Nationals have accumulated an OBP of .308 as well as a batting average of .245 for the season.

The Washington pitching staff have yielded 798 runs on the year while having a team ERA of 5.30 (753 earned runs surrendered). They have conceded 190 homers and they relinquish 5.61 runs per 9 innings (29th in MLB). The Nationals have a WHIP of 1.433 in addition to having a FIP of 4.71 as a squad on the campaign. They have earned a strikeout to walk ratio of 7.80 (1,114 strikeouts vs 505 free passes). They are sitting at 29th in baseball as a pitching staff in total hits given up with 1,328.

Washington relievers have an inherited score rate of 39.2% out of 245 inherited runners. Their relievers have taken the field 111 times in high leverage situations and also on 144 occasions with runners on base. Sitting with 114 save situations, the Nationals have amassed 66 holds and also 16 blown saves. They rank 8th in the league with a save rate of 66.0%, and they have dispatched 519 relief pitchers onto the diamond so far this season. Washington has had relief pitchers take the mound in 47 save chances and they have walked away with 31 saves.

In their 11,514 innings played, the Nationals have accumulated a efficiency on defense of 68.3% (28th in MLB). The Washington Nationals have turned 115 double plays and have a fielding percentage of .984 (21st in pro baseball). The Nationals have recorded 1,244 assists, 82 errors and have a total of 3,838 putouts so far this season.

During his MLB career, Cavalli has surrendered 48 hits while tallying 35 strikeouts in 38 frames. Cavalli (3-2 record in his career) is the owner of a 5.87 earned run average and has surrendered 11.3 hits per nine innings. He has surrendered a total of 25 ER's while holding a WHIP of 1.540 and being the owner of a FIP of 5.8. His K/BB ratio is 3.18 and he has faced 179 opposing batters so far in his MLB career.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Pittsburgh (-132)

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