San Diego Padres vs Cincinnati Reds Prediction, 6/27/2025 MLB Picks, Best Bets & Odds

Game: San Diego Padres vs Cincinnati Reds

Date: Friday, June 27, 2025

Location: Great American Ball Park in Cincinnati, OH

TV: FanDuel Sports Network Ohio

Odds/Point Spread: San Diego (-130) Cincinnati (+110)

The Cincinnati Reds (42-39) will compete against the San Diego Padres (44-36) at Great American Ball Park on Friday. The moneyline on this contest has the Padres at -130 and the Reds are at +110. The total comes in at 9. The starting pitchers are Dylan Cease and Nick Martinez.

San Diego has a slugging rate of .379 and have been called out on strikes 561 times, while being walked on 252 occasions. They have 312 RBI's as well as 661 base knocks for the year, and their team batting average sits at .248. The Padres have compiled 118 doubles as a squad and have smacked 69 baseballs out of the park. They have earned 336 runs scored while holding a team OBP of .316. As a squad, the San Diego Padres are notching 4.2 runs/g, which has them at 21st in the league.

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The Padres have compiled a team ERA of 3.59 this year (9th in baseball), and their staff has struck out 697 hitters. Padres pitchers have given up 79 home runs and 313 runs in total (9th in baseball). Their pitching staff has walked 262 batters and their FIP sits at 3.80 as a squad this year. San Diego has surrendered 600 base knocks (7.6 per 9 innings) as well as 283 earned runs. They have earned a strikeout to walk ratio of 2.66 and the pitching staff holds a collective WHIP of 1.22.

The Padres have sent 281 relief pitchers to the mound on the season. The relief pitchers have inherited 127 runners this year with 35.4% of those runners ended up scoring. They have tallied 27 saves this year and have blown 9 of their 36 save opportunities. The Padres relief pitchers have a save percentage of 75.0% and have come into the game in 89 save situations. The relievers are sitting with 52 holds this year (9th in the league). Padres bullpen pitchers have gone to the mound with runners on base 90 times in addition to having 111 appearances in high leverage situations.

The Padres have converted 71.2% of baseballs in play into outs out of 6,378 innings on the field, ranking them 6th in professional baseball. The San Diego Padres have earned 2,126 putouts this season, in addition to 607 assists and 39 errors. Their fielding percentage is at .986 which has them sitting 18th in professional baseball, and have 56 double plays.

Cease has pitched in 934 frames and has earned 1,125 strikeouts in his pro baseball career. His earned run average is 3.82 (396 earned runs allowed) and his career WHIP is 1.257. He has surrendered 782 hits (7.5 hits per 9 innings) and has had 392 free passes. Cease (60-52 win-loss record in his career) has a FIP of 3.76 while he has gone up against 3,955 hitters during his time in the majors.

The Reds hold a slugging % of .401 and they score 4.59 runs per contest (12th in baseball). They have 135 doubles, while taking a walk 274 times as well as putting up 372 runs. Cincinnati is sitting with 88 long balls so far this season and 356 runs batted in. They have been called out on strikes on 704 occasions (9th in the league) and have earned 670 base knocks. The Cincinnati Reds have an on-base percentage of .319 in addition to a team batting average of .247 over the course of the season.

The Reds hold a team WHIP of 1.220 and have a FIP of 4.17 as a staff on the year. They come in at 9th in baseball as a staff in total hits allowed with 627. The Cincinnati pitching staff have yielded 338 runs this season and come in with a team ERA of 3.85 (307 earned runs given up). Their K/BB ratio sits at 8.20 (657 strikeouts against 248 walks). They have surrendered 96 HR's and they give up 4.24 runs per 9 innings (16th in MLB).

Cincinnati relief pitchers hold an inherited score percentage of 33.0% of 94 inherited base runners. Their relievers have taken the field 72 times in high leverage situations and on 62 occasions with runners on base. Sitting with 84 save situations, the Reds have 52 holds in addition to 9 blown saves. They sit at 6th in baseball holding a save percentage of 70.0%, and they have sent 274 relief pitchers to the hill this season. Cincinnati has called on relievers to enter the game in 30 save chances and they have earned 21 saves.

The Cincinnati Reds have gotten 48 double plays and have a fielding percentage of .986 (15th in professional baseball). The Reds have recorded 613 assists, 38 errors and have earned 2,153 putouts for the year. In their 6,459 innings on the field, the Reds have accumulated a defensive efficiency of 71.9% (3rd in baseball).

Martinez (41-53 career win-loss record) has a 4.12 earned run average while allowing 9.0 hits per nine innings. He has a K/BB ratio of 2.32 and he has gone up against 3,658 opposing batters in his career. He has allowed 394 ER's while holding a WHIP of 1.314 and having a FIP of 4.1. Thus far in his career, Martinez has surrendered 864 base hits and he has 617 punch outs in 860 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take San Diego (-130)

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