San Diego Padres vs Cincinnati Reds Prediction, 6/29/2025 MLB Picks, Best Bets & Odds

Game: San Diego Padres vs Cincinnati Reds

Date: Sunday, June 29, 2025

Location: Great American Ball Park in Cincinnati, OH

TV: FanDuel Sports Network Ohio

Odds/Point Spread: San Diego (-275) Cincinnati (+220)

The San Diego Padres (44-36) are traveling to Great American Ball Park on Sunday where they will take on the Cincinnati Reds (42-39). The odds on this game have San Diego at -275 and Cincinnati is sitting at +220. The betting total is set at 9. The men taking the mound will be Stephen Kolek and Nick Lodolo.

San Diego is slugging .379 and have been called out on strikes 561 times, while drawing a walk on 252 occasions. They have amassed 312 runs batted in in addition to 661 base knocks on the campaign, while their average at the plate is .248. The Padres have hit 118 doubles as a squad and have smacked 69 baseballs out of the stadium. They have notched a total of 336 runs while holding a team on-base percentage of .316. As a unit, the San Diego Padres are putting up 4.2 runs/g, which puts them at 19th in the league.

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The Padres hold a team ERA of 3.59 this year (9th in MLB), and the staff has rung up 697 hitters. Padres pitchers have conceded 79 long balls in addition to 313 runs (9th in baseball). Their pitching staff has walked 262 opposing hitters and their FIP comes in at 3.80 as a team on the year. San Diego has yielded 600 base knocks (7.6 per 9 innings) and 283 earned runs. They have a K/BB ratio of 2.66 and the pitching staff has earned a collective WHIP of 1.22.

The Padres have sent 281 relievers to the hill on the season. The relievers have inherited 127 base runners this year and 35.4% of those runners ended up scoring. They have recorded 27 saves on the campaign and have blown 9 of 36 chances to save the game. The Padres bullpen have a save percentage of 75.0% and have come into the game in 89 save situations. The bullpen have accumulated 52 holds this year (10th in MLB). Padres relief pitchers have entered the game with opponents on base 90 times as well as having 111 appearances in high leverage situations.

The San Diego Padres have earned 2,126 putouts at this point in the season, in addition to 607 assists and 39 errors. Their fielding percentage is holding steady at .986 which puts them in 18th in MLB, and have a total of 56 double plays. The Padres have turned 71.2% of balls hit into play into outs out of their 6,378 innings on the field, which has them sitting at 6th in pro baseball.

Kolek has thrown 103 frames and has earned 81 strikeouts so far in his career. Kolek (6-3 career record) sits with a FIP of 4.47 while he has faced 452 hitters in the majors. His earned run average is 4.53 (52 ER's allowed) and his career WHIP is 1.405. He has given up 113 hits (9.9 hits per 9 innings) with 32 free passes.

The Reds hold a team slugging % of .401 and they earn 4.59 runs per contest (10th in the league). They have recorded 135 doubles, while getting a free base 274 times as well as putting up 372 runs. Cincinnati has hit 88 home runs this year and 356 runs batted in. They have been called out on strikes on 704 occasions (10th in baseball) and have earned 670 hits. The Cincinnati Reds are sitting with a team on-base percentage of .319 as well as a batting average of .247 this year.

The Reds have a team WHIP of 1.220 in addition to having a FIP of 4.17 as a staff so far this year. They have a ranking of 7th in baseball as a staff in total hits surrendered with 627. The Cincinnati pitching staff have given up 338 runs this year while having a team ERA of 3.85 (307 earned runs surrendered). They have earned a K/BB ratio of 8.20 (657 strikeouts against 248 walks). They have relinquished 96 HR's and they relinquish 4.24 runs per 9 innings (15th in the league).

Cincinnati has called on relievers to enter the contest in 30 save chances and they have tallied 21 saves. They rank 6th in baseball with a save rate of 70.0%, and they have sent 274 bullpen pitchers onto the diamond this season. Their bullpen pitchers have come in 72 times in high leverage situations in addition to 62 occasions with runners on base. Cincinnati relievers hold an inherited score percentage of 33.0% of 94 inherited base runners. With 84 save situations, the Reds have recorded 52 holds and 9 blown saves.

In their 6,459 innings on the field, the Reds are sitting with a efficiency on defense of 71.9% (3rd in the majors). The Cincinnati Reds have gotten 48 double plays and have notched a fielding percentage of .986 (15th in the majors). The Reds have recorded 613 assists, 38 errors and have amassed 2,153 putouts during this campaign.

In his MLB career, Lodolo has allowed 323 hits while he has accumulated 380 punch outs in 342 innings. He has given up a total of 163 earned runs while earning a WHIP of 1.248 and a FIP of 4.2. His K/BB ratio is 3.65 and he has faced 1,472 opposing hitters in his MLB career. Lodolo (20-19 career mark) has earned a 4.29 earned run average and has conceded 8.5 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take San Diego (-275)

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