San Diego Padres vs Milwaukee Brewers Prediction, 6/6/2025 MLB Picks, Best Bets & Odds

Game: San Diego Padres vs Milwaukee Brewers

Date: Friday, June 6, 2025

Location: American Family Field in Milwaukee, WI

TV: FanDuel Sports Network Wisconsin

Odds/Point Spread: San Diego (-160) Milwaukee (+132)

The Milwaukee Brewers (34-29) are welcoming the San Diego Padres (35-25) at American Family Field on Friday. The odds on this game have San Diego at -160 while Milwaukee is at +132. The total is set at 8.5. The pitchers taking the mound are Randy Vasquez and Chad Patrick.

The Padres have recorded 88 doubles as a unit and have knocked 53 balls out of the park. San Diego has a slugging rate of .381 and have struck out 415 times, while taking a walk on 186 occasions. As a unit, the San Diego Padres are compiling 4.2 runs per contest, which ranks them 17th in the league. They have accrued 231 RBI's and 498 base knocks for the year, and their batting average is .249. They have earned 251 runs while holding a team on-base percentage of .315.

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They have a strikeout to walk ratio of 2.72 and the pitching staff holds a collective WHIP of 1.20. Padres pitchers have given up 62 home runs and also 234 runs in total (11th in MLB). San Diego has allowed 449 base knocks (7.6 per 9 innings) and 211 earned runs. The Padres hold a team ERA of 3.56 for the season (8th in baseball), and their staff has struck out 523 hitters. Their pitching staff has walked 192 hitters and their FIP is 3.83 as a unit over the course of the season.

Padres relief pitchers have entered the game with runners on base 66 times as well as having 83 appearances in high leverage situations. The relief pitchers have a total of 40 holds on the campaign (11th in MLB). The Padres relievers have a save percentage of 73.3% and have stepped onto the mound in 71 save situations. They have accumulated 22 saves this year and have blown 8 of their 30 chances to save the game. The relief pitchers have inherited 91 base runners on the year and 38.5% of those runners crossed home plate. The Padres have dispatched 209 relievers to the hill this year.

The San Diego Padres have 1,602 putouts thus far, in addition to 467 assists and 31 errors. Their fielding percentage is currently at .985 which has them sitting 18th in professional baseball, and have a total of 47 double plays. The Padres have converted 71.3% of balls in play into outs out of their 4,806 innings, which has them ranked 7th in professional baseball.

Vasquez has pitched in 193 innings and has earned 130 K's so far in his career. Vasquez (9-13 mark in his career) holds a FIP of 4.17 while he has gone up against 854 opposing hitters during his time in the major leagues. His earned run average is 4.23 (91 earned runs allowed) and his WHIP is 1.458. He has surrendered 205 hits (9.5 hits per 9 innings) and has 77 walks.

Milwaukee has tallied 58 long balls over the course of the season as well as 265 RBIs. They have recorded 89 doubles, while getting a free base 216 times and scoring 288 runs. The Milwaukee Brewers have earned an on-base percentage of .315 as well as a team batting average of .239 this year. The Brewers hold a slugging % of .368 and they are recording 4.57 runs per game (9th in baseball). They have struck out on 512 occasions (16th in MLB) and have accounted for 505 base hits.

The Brewers hold a team WHIP of 1.318 with a FIP of 4.13 as a team this season. They are sitting at 20th in MLB as a pitching staff in total hits relinquished with 504. The Milwaukee pitching staff have surrendered 263 runs this season while holding a team ERA of 3.91 (242 earned runs relinquished). Their K/BB ratio is 8.30 (512 strikeouts vs 230 bases on balls). They have yielded 66 home runs and they give up 4.25 runs per 9 innings (15th in baseball).

Milwaukee relief pitchers hold an inherited score percentage of 34.7% out of their 98 inherited base runners. Their bullpen pitchers have stepped onto the hill 78 times in high leverage situations and on 64 occasions with runners on. Sitting with 67 save situations, the Brewers have earned 41 holds in addition to 9 blown saves. They are currently ranked 18th in baseball holding a save rate of 62.5%, and they have sent 227 relievers to the hill over the course of the season. Milwaukee has called on bullpen pitchers to take the mound in 24 save opportunities and they have walked away with 15 saves.

In their 5,016 innings on the field, the Brewers have a defensive efficiency of 70.3% (15th in MLB). The Milwaukee Brewers have gotten 44 double plays and hold a fielding percentage of .984 (24th in professional baseball). The Brewers have racked up 498 assists, 36 errors and have earned a total of 1,672 putouts on the campaign.

Thus far in his career, Patrick has surrendered 59 hits and he has 57 punch outs in 63 innings pitched. Patrick (3-4 career mark) has earned a 2.99 earned run average while giving up 8.4 hits per nine innings. He has given up 21 earned runs while holding a WHIP of 1.218 and being the owner of a FIP of 2.9. He has a strikeout to walk ratio of 3.17 and he has gone up against 264 hitters so far in his pro baseball career.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take San Diego (-160)

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