San Diego Padres vs Minnesota Twins Prediction, 8/29/2025 MLB Picks, Best Bets & Odds

Game: San Diego Padres vs Minnesota Twins

Date: Friday, August 29, 2025

Location: Target Field in Minneapolis, MN

TV: Twins.TV

Odds/Point Spread: San Diego (-150) Minnesota (+125)

Target Field is the site where the Minnesota Twins (60-73) will take on the San Diego Padres (75-59) on Friday. The odds on this game have San Diego at -150 while Minnesota is priced at +125. The total is 8. The pitchers who are expected to start will be Nestor Cortes and Zebby Matthews.

The Padres have tallied 219 doubles as a team and have knocked 116 baseballs out of the park. San Diego has a slugging percentage of .385 and have struck out 938 times, while taking a walk on 430 occasions. As a team, the San Diego Padres are scoring 4.2 runs per outing, which has them at 23rd in MLB. They have amassed 529 RBI's and 1,123 hits for the season, and their batting average sits at .251. They have racked up 564 runs scored while having a team OBP of .321.

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The Padres have a team earned run average of 3.60 this year (2nd in the league), and the staff has rung up 1,150 batters. Padres pitchers have surrendered 139 long balls and 510 runs (2nd in MLB). They have walked 437 opposing players and their FIP is 3.95 as a squad on the year. San Diego has given up 977 hits (7.4 per 9 innings) and also 473 earned runs. They have accumulated a K/BB ratio of 2.63 and their pitching staff sits with a WHIP of 1.19.

The Padres have dispatched 470 relief pitchers to the hill for the season. The relief pitchers have inherited 218 runners on the campaign and 28.0% of them ended up crossing the plate. They have earned 43 saves over the course of the season and have blown 15 out of their 58 chances to get a save. The Padres bullpen have recorded a save rate of 74.1% and have come into the game in 153 save situations. The relief pitchers have racked up 90 holds so far this year (4th in baseball). Padres bullpen pitchers have entered the game with runners on base 154 times in addition to having 182 appearances in high leverage situations.

The Padres have turned 72.1% of baseballs in play into outs out of 10,656 innings on the diamond, ranking them 2nd in professional baseball. The San Diego Padres have a tally of 3,552 putouts on the campaign, in addition to 1,010 assists and 61 errors. Their fielding percentage is at .987 which is 12th in the majors, and have accumulated 100 double plays.

Cortes Jr (35-23 career win-loss mark) has earned a FIP of 3.79 while he has faced 2,458 hitters in the major leagues. He has surrendered 525 base knocks (7.9 hits per 9 innings) and has had 175 walks. His ERA is 3.84 (255 earned runs allowed) and he has a WHIP of 1.173. Cortes Jr has taken the hill for 597 innings and has earned 600 strikeouts so far in his career.

The Minnesota Twins have a team OBP of .310 as well as a team batting average of .238 this season. They have been rung up on 1,105 instances (15th in baseball) and have earned a total of 1,058 base knocks. Minnesota has recorded 159 home runs this season as well as 530 RBIs. The Twins have a slugging percentage of .398 and they are earning 4.18 runs per game (24th in the league). They have 204 doubles, while getting a free base 403 times as well as recording 556 runs.

The Twins hold a team WHIP of 1.307 with a FIP of 4.07 as a pitching staff for the year. Their strikeout to walk ratio comes in at 8.60 (1,113 strikeouts vs 368 bases on balls). They are sitting at 24th in MLB as a pitching staff in total hits conceded with 1,161. They have conceded 159 home runs and they concede 4.75 runs per 9 innings (23rd in MLB). The Minnesota pitching staff have allowed 618 runs for the year while holding an ERA of 4.44 (577 earned runs surrendered).

Minnesota has had relief pitchers step onto the mound in 44 save opportunities and they have recorded 25 saves. They are ranked 25th in baseball with a save percentage of 56.8%, and they have sent 454 relief pitchers onto the field so far this season. Their relief pitchers have stepped onto the hill 155 times in high leverage situations and on 100 occasions with runners on. Minnesota bullpen pitchers have an inherited score percentage of 35.7% of 143 inherited base runners. With 127 save situations, the Twins have amassed 81 holds and also 19 blown saves.

The Minnesota Twins have turned 80 double plays and hold a fielding percentage of .987 (14th in the majors). The Twins have racked up 991 assists, 61 errors and have notched a total of 3,510 putouts so far this season. In 10,530 innings on the field, the Twins have accumulated a efficiency on defense of 68.6% (27th in MLB).

In his pro baseball career, Matthews has surrendered 113 base hits and he has 110 punch outs in 89 innings. Matthews (4-8 career record) is the owner of a 5.94 earned run average while giving up 11.4 hits per 9 innings. He has given up 59 ER's while earning a WHIP of 1.588 and a FIP of 5.9. His K/BB ratio is 3.79 and he has faced 412 hitters in his MLB career.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Minnesota (+125)

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