San Diego Padres vs San Francisco Giants Prediction, 8/13/2025 MLB Picks, Best Bets & Odds

Game: San Diego Padres vs San Francisco Giants

Date: Wednesday, August 13, 2025

Location: Oracle Park in San Francisco, CA

TV: NBC Bay Area

Odds/Point Spread: San Diego (-150) San Francisco (+125)

The San Diego Padres (66-52) are on their way to Oracle Park on Wednesday where they will meet the San Francisco Giants (59-59). The odds on this game have San Diego at -150 while San Francisco is priced at +125. The over/under is 9. The pitchers expected to start will be Nick Pivetta and Justin Verlander.

San Diego has a slugging percentage of .380 and have struck out 827 times, while being walked on 387 occasions. They have recorded 460 runs batted in in addition to 988 base knocks this season, while their batting average sits at .251. The Padres have tallied 180 doubles as a team and have knocked 99 baseballs out of the park. They have earned a total of 489 runs scored and hold an on-base percentage of .321. As a squad, the San Diego Padres are scoring 4.1 runs/g, which puts them at 23rd in MLB.

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The Padres have compiled a team earned run average of 3.62 so far this season (3rd in baseball), and their staff has rung up 1,010 batters. Padres pitchers have allowed 115 home runs and 454 total runs (3rd in the league). Their pitching staff has walked 390 batters and their FIP comes in at 3.87 as a unit on the season. San Diego has surrendered 880 hits (7.6 per 9 innings) as well as 420 earned runs. Their K/BB ratio is 2.59 and the pitching staff has earned a collective WHIP of 1.22.

The Padres relievers have accumulated a save percentage of 72.2% and have come into the game in 139 save situations. The relievers have inherited 197 base runners over the course of the season with 28.9% of them ended up crossing the plate. Padres relief pitchers have stepped onto the hill with players on base 140 times as well as having 168 appearances in high leverage situations. The Padres have dispatched 416 relief pitchers to the hill on the year. The relief pitchers have notched 82 holds on the campaign (3rd in MLB). They have tallied 39 saves this year and have blown 15 of 54 save chances.

The Padres have turned 71.4% of balls hit into play into outs out of their 9,405 innings, which has them ranked 2nd in the majors. The San Diego Padres have earned 3,135 putouts for the season, in addition to 908 assists and 56 errors. Their fielding percentage is holding steady at .986 which has them sitting 16th in MLB, and they have turned 92 double plays.

Pivetta (67-75 record in his career) has earned a FIP of 4.48 while he has faced 4,916 opposing hitters during his time in the majors. He has allowed 1,072 hits (8.3 hits per 9 innings) with 412 walks. His earned run average is 4.55 (588 earned runs allowed) and his WHIP is 1.276. Pivetta has thrown 1,163 innings and has tallied 1,278 K's thus far in his career.

The San Francisco Giants have accounted for an on-base percentage of .311 in addition to a batting average of .233 for the year. They have been called out on strikes on 999 instances (13th in the league) and have tallied 911 hits. San Francisco has recorded 112 home runs for the year to go along with 467 RBIs. The Giants have a team slugging % of .376 and they are earning 4.14 runs per game (24th in baseball). They have hit 178 doubles, while taking a walk 407 times as well as earning 488 runs.

The San Francisco pitching staff have allowed 477 runs over the course of the season and come in with a team ERA of 3.64 (423 earned runs conceded). They have relinquished 102 dingers and they relinquish 4.11 runs per 9 innings (7th in baseball). The Giants are sitting with a team WHIP of 1.280 in addition to having a FIP of 3.65 as a pitching staff for the season. Their strikeout to walk ratio sits at 8.70 (1,007 strikeouts vs 374 walks). They come in at 16th in the league as a staff in total hits given up with 964.

Sitting with 114 save situations, the Giants have earned 69 holds in addition to 17 blown saves. San Francisco has had relief pitchers enter the contest in 45 save chances and they have tallied 28 saves. Their relievers have come in 131 times in high leverage situations and also on 83 occasions with runners on. San Francisco relief pitchers hold an inherited score percentage of 33.3% of 129 inherited runners. They are ranked 16th in MLB holding a save rate of 62.2%, and they have sent 374 relievers to the mound over the course of the season.

The San Francisco Giants have gotten 91 double plays and have earned a fielding percentage of .985 (22nd in the majors). The Giants have racked up 1,098 assists, 66 errors and have earned a total of 3,135 putouts over the course of the season. Out of their 9,405 innings on the diamond, the Giants have earned a defensive efficiency of 68.8% (25th in pro baseball).

Verlander (263-156 mark in his career) is the owner of a 3.33 ERA and has conceded 7.7 hits per 9 innings. He has a strikeout to walk ratio of 3.55 and he has faced 14,389 opposing hitters during his pro baseball career. He has given up 1,302 ER's while earning a WHIP of 1.136 and a FIP of 3.3. During his MLB career, Verlander has conceded 3,004 base hits while he has tallied 3,503 punch outs in 3,514 frames.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take San Diego (-150)

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