San Diego Padres vs Seattle Mariners Prediction, 8/25/2025 MLB Picks, Best Bets & Odds
Game: San Diego Padres vs Seattle Mariners
Date: Monday, August 25, 2025
Location: T-Mobile Park in Seattle, WA
TV: Root Sports Northwest
Odds/Point Spread: San Diego (-182) Seattle (+150)
The San Diego Padres (72-56) are on their way to T-Mobile Park on Monday where they will go up against the Seattle Mariners (68-60). The moneyline on this contest has San Diego at -182 while Seattle is coming in at +150. The over/under is 9. The starting pitchers will be JP Sears and Bryce Miller.


San Diego has a slugging rate of .385 and have been rung up 893 times, while taking a walk on 414 occasions. They have compiled 504 RBI's as well as 1,079 hits so far this season, and their batting average is at .252. The Padres have compiled 208 doubles as a squad and have hit 110 baseballs out of the park. They are sitting with 539 runs while holding a team on-base percentage of .322. As a squad, the San Diego Padres are compiling 4.2 runs per game, which has them at 22nd in the league.
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The Padres are sitting with a team earned run average of 3.54 on the campaign (2nd in the league), and their staff has rung up 1,103 hitters. Padres pitchers have surrendered 128 home runs and also 481 total runs (2nd in the league). Their pitching staff has walked 420 opposing players and their FIP comes in at 3.89 as a squad over the course of the season. San Diego has allowed 938 base hits (7.5 per 9 innings) and 445 earned runs. They have a strikeout to walk ratio of 2.63 and their pitching staff has a collective WHIP of 1.20.
The Padres have sent 449 relief pitchers to the hill so far this season. The relievers have inherited 211 runners for the year with 27.0% of them crossed home plate. They have recorded 40 saves for the year and have blown 15 out of their 55 save opportunities. The Padres bullpen have a save rate of 72.7% and have come into the game in 143 save situations. The relief pitchers have racked up 84 holds on the season (6th in MLB). Padres relief pitchers have entered the contest with runners on base 149 times in addition to having 172 appearances in high leverage situations.
The Padres have turned 71.8% of baseballs in play into outs in their 10,188 innings, which has them ranked 2nd in professional baseball. The San Diego Padres are sitting with 3,396 putouts thus far, in addition to 969 assists and 58 errors. Their fielding percentage is holding steady at .987 which has them ranked 12th in the majors, and they have turned 97 double plays.
Sears has taken the mound for 545 frames and has earned 452 strikeouts during his MLB career. His ERA is 4.49 (272 ER's allowed) and he has a WHIP of 1.259. He has conceded 530 hits (8.8 hits per nine innings) with 156 free passes. Sears (30-40 career record) sits with a FIP of 4.42 while going up against 2,302 hitters in the major leagues.
Seattle is sitting with 180 home runs on the year to go along with 558 RBIs. They have notched 177 doubles, while taking a walk 430 times and scoring 582 runs. The Seattle Mariners are sitting with an on-base percentage of .318 in addition to a batting average of .243 on the year. The Mariners hold a slugging % of .410 and they have an average of 4.55 runs per game (10th in the league). They have struck out on 1,155 occasions (3rd in the league) and have tallied 1,058 base knocks.
The Mariners have a WHIP of 1.263 and are the owners of a FIP of 4.13 as a squad for the year. They are currently ranked 22nd in baseball as a pitching staff in total hits allowed with 1,074. The Seattle pitching staff have conceded 567 runs over the course of the season while having a team ERA of 3.99 (512 earned runs yielded). Their K/BB ratio sits at 8.50 (1,086 strikeouts against 385 free passes). They have given up 155 homers and they surrender 4.42 runs per 9 innings (17th in the league).
Sitting with 122 save situations, the Mariners have tallied 69 holds and also 20 blown saves. Seattle has had relievers step onto the mound in 53 save opportunities and they have tallied 33 saves. Their relief pitchers have come in 176 times in high leverage situations and on 108 occasions with base runners. Seattle relievers hold an inherited score percentage of 25.4% out of 118 inherited runners. They are ranked 17th in MLB with a save rate of 62.3%, and they have dispatched 431 relievers onto the diamond so far this year.
The Seattle Mariners have gotten 93 double plays and have a fielding percentage of .988 (6th in the majors). The Mariners have racked up 1,074 assists, 53 errors and have accounted for 3,466 putouts on the campaign. In 10,398 innings played, the Mariners hold a efficiency on defense of 70.3% (13th in MLB).
Miller (22-20 mark in his career) has earned a 3.88 earned run average while giving up 7.7 hits per 9 innings. He has a K/BB ratio of 3.47 and he has faced 1,479 batters in his pro baseball career. He has given up 157 earned runs while earning a WHIP of 1.117 and being the owner of a FIP of 3.8. During his MLB career, Miller has given up 311 hits while he has tallied 333 K's in 364 innings pitched.
Who will win tonight's MLB game against the spread or moneyline?
Tony Sink's Pick: Take San Diego (-182)
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Additional Resources:
Seattle Mariners - Twitter
San Diego Padres - Twitter