San Francisco Giants vs Chicago White Sox Prediction, 6/29/2025 MLB Picks, Best Bets & Odds
Game: San Francisco Giants vs Chicago White Sox
Date: Sunday, June 29, 2025
Location: Rate Field in Chicago, IL
TV: Chicago Sports Network
Odds/Point Spread: San Francisco (-196) Chicago (+162)
The San Francisco Giants (44-37) are on their way to Rate Field on Sunday where they will take on the Chicago White Sox (26-55). The odds on this game have San Francisco at -196 while Chicago is priced at +162. The betting total is set at 9. The starting pitchers are Justin Verlander and Shane Smith.


The Giants have hit 117 doubles as a team and have hit 79 baseballs out of the park. San Francisco has a slugging rate of .375 and have been called out on strikes 677 times, while drawing a walk on 289 occasions. As a squad, the San Francisco Giants are putting up 4.3 runs per game, which ranks them 16th in baseball. They have compiled 325 RBI's as well as 616 base knocks this season, and their team batting average comes in at .232. They have 344 runs scored while holding a team on-base percentage of .313.
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They have accumulated a K/BB ratio of 2.73 and their pitching staff has earned a collective WHIP of 1.24. Giants pitchers have conceded 64 long balls and 310 runs in total (7th in baseball). San Francisco has conceded 634 base hits (8.0 per 9 innings) and 273 earned runs. The Giants hold a team ERA of 3.42 so far this year (5th in the league), and they have struck out 696 hitters. Their pitching staff has walked 255 opposing hitters and their FIP comes in at 3.46 as a squad on the season.
The Giants have sent 254 relievers to the hill on the year. The relievers have inherited 92 base runners this season with 32.6% of them ended up crossing the plate. They have recorded 23 saves so far this season and have blown 12 of their 35 save opportunities. The Giants relief pitchers have recorded a save rate of 65.7% and stepped onto the hill in 92 save situations. The relief pitchers have earned 57 holds this season (4th in the league). Giants bullpen pitchers have entered the contest with runners on 57 times and also have had 96 appearances in high leverage situations.
The Seattle Mariners have amassed 2,153 putouts for the season, as well as 763 assists and 44 errors. Their fielding percentage is at .985 which puts them in 21st in the majors, and they have turned 57 double plays. The Giants have turned 69.5% of baseballs in play into outs out of 6,459 innings, which has them sitting 18th in baseball.
Verlander has taken the hill for 3,476 innings and has totaled 3,468 K's so far in his MLB career. His earned run average is 3.32 (1,283 ER's allowed) and his WHIP is 1.130. He has surrendered 2,955 hits (7.7 hits per 9 innings) and has had 975 walks. Verlander (262-152 record in his career) sits with a FIP of 3.27 and he has faced 14,213 hitters during his time in the major leagues.
Chicago has recorded 64 HRs on the campaign and 267 runs batted in. They have recorded 123 doubles, while getting a free base 266 times as well as scoring 280 runs. The Chicago White Sox have tallied an OBP of .293 as well as a team batting average of .220 for the season. The White Sox hold a team SLG% of .345 and they are earning 3.46 runs per contest (28th in the league). They have been called out on strikes on 707 instances (8th in MLB) and have notched a total of 583 base knocks.
The White Sox have a WHIP of 1.403 in addition to having a FIP of 4.50 as a unit on the season. Their K/BB ratio sits at 7.50 (584 strikeouts vs 293 free passes). They come in at 23rd in MLB as a staff in total hits allowed with 692. They have relinquished 88 home runs and they surrender 4.64 runs per 9 innings (23rd in MLB). The Chicago pitching staff have surrendered 362 runs on the season while holding an ERA of 4.18 (326 earned runs relinquished).
Chicago relievers hold an inherited score percentage of 27.9% out of 111 inherited base runners. Their relievers have come in 73 times in high leverage situations and also on 77 occasions with base runners. Sitting with 61 save situations, the White Sox have amassed 39 holds in addition to 14 blown saves. They sit at 30th in MLB holding a save percentage of 36.4%, and they have dispatched 259 relievers to the hill this season. Chicago has had relief pitchers enter the game in 22 save opportunities and they have walked away with 8 saves.
The Chicago White Sox have gotten 67 double plays and have a fielding rate of .981 (27th in professional baseball). The White Sox have 666 assists, 53 errors and have a tally of 2,107 putouts so far this season. In their 6,321 innings on the field, the White Sox have a efficiency on defense of 69.1% (20th in MLB).
In his career, Smith has given up 63 base knocks while totaling 68 strikeouts in 74 innings pitched. Smith (3-5 career record) holds a 3.40 earned run average while giving up 7.6 hits per nine innings. He has surrendered 28 ER's while holding a WHIP of 1.280 and being the owner of a FIP of 3.3. He has a strikeout to walk ratio of 2.13 and he has gone up against 323 batters during his career.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take Chicago (+162)
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Additional Resources:
Chicago White Sox - Twitter
San Francisco Giants - Twitter