San Francisco Giants vs Detroit Tigers Prediction, 5/28/2025 MLB Picks, Best Bets & Odds

Game: San Francisco Giants vs Detroit Tigers

Date: Wednesday, May 28, 2025

Location: Comerica Park in Detroit, MI

TV: FanDuel Sports Network Detroit

Odds/Point Spread: San Francisco (+110) Detroit (-132)

The Detroit Tigers (35-20) will take on the San Francisco Giants (31-23) at Comerica Park on Wednesday. The moneyline on this game has the Giants at +110 while the Tigers open at -132. The over/under comes in at 8. The starting pitchers will be Landen Roupp and Jackson Jobe.

As a squad, the San Francisco Giants are putting up 4.4 runs per game, which has them sitting at 11th in the league. They have earned 238 runs while holding a team on-base percentage of .308. The Giants have hit 80 two-baggers as a team and have smacked 54 baseballs out of the park. They have accumulated 227 RBI's as well as 411 base knocks this year, and their average at the plate is at .231. San Francisco is slugging .376 and have been rung up 455 times, while drawing a walk on 190 occasions.

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The Giants hold a team ERA of 3.25 over the course of the season (3rd in baseball), and their staff has rung up 454 batters. Giants pitchers have allowed 40 home runs in addition to 196 total runs (7th in the league). They have walked 160 batters and their FIP is 3.36 as a team this season. San Francisco has allowed 415 base hits (7.8 per 9 innings) in addition to 172 earned runs. Their strikeout to walk ratio is 2.84 and the pitching staff has a collective WHIP of 1.21.

The Giants bullpen have accumulated a save rate of 65.2% and have come into the game in 57 save situations. The bullpen pitchers have inherited 53 runners on the year with 43.4% of them ended up crossing the plate. Giants relief pitchers have gone to the mound with runners on base 31 times and also have had 57 appearances in high leverage situations. The Giants have dispatched 161 relief pitchers to the mound over the course of the season. The relievers have racked up 34 holds over the course of the season (10th in baseball). They have recorded 15 saves this season and have blown 8 of 23 save opportunities.

The Giants have transformed 69.8% of baseballs in play into outs in their 4,284 innings, which has them sitting 17th in baseball. The Seattle Mariners are sitting with 1,428 putouts thus far, as well as 526 assists and 29 errors. Their fielding rate is holding at .985 which has them ranked 19th in pro baseball, and they have turned 43 double plays.

Roupp (4-5 win-loss record in his career) is the owner of a FIP of 3.56 while he has faced 444 batters in the major leagues. He has allowed 98 hits (8.6 hits per nine innings) and has 44 walks. His ERA is 3.61 (41 ER's allowed) and he has a WHIP of 1.391. Roupp has taken the mound for 102 frames and has 96 strikeouts during his career.

The Tigers hold a team slugging % of .410 and they have an average of 5.11 runs per outing (4th in MLB). They have notched 86 doubles, while walking 187 times as well as earning 281 runs. Detroit has accounted for 64 long balls for the season to go along with 268 runs batted in. They have struck out on 481 occasions (5th in the league) and are sitting with 471 base hits. The Detroit Tigers have compiled an OBP of .326 and a team batting average of .253 so far this season.

The Tigers hold a team WHIP of 1.155 in addition to having a FIP of 3.71 as a staff on the season. They are currently ranked 7th in MLB as a pitching staff in total hits surrendered with 408. The Detroit pitching staff have relinquished 200 runs on the season while having an ERA of 3.27 (178 earned runs conceded). They have earned a K/BB ratio of 8.80 (477 strikeouts against 158 walks). They have relinquished 55 home runs and they give up 3.67 runs per 9 innings (6th in baseball).

Detroit has called on relievers to step onto the mound in 23 save opportunities and they have earned 15 saves. They sit at 11th in the league with a save percentage of 65.2%, and they have dispatched 163 relievers onto the field this year. Their relief pitchers have stepped onto the hill 46 times in high leverage situations and on 58 occasions with runners on. Detroit relievers hold an inherited score percentage of 28.8% out of 80 inherited runners. Sitting with 53 save situations, the Tigers have 28 holds and 8 blown saves.

The Detroit Tigers have turned 39 double plays and have accounted for a fielding rate of .988 (7th in the majors). The Tigers have accrued 466 assists, 23 errors and have a total of 1,470 putouts for the season. Out of their 4,410 innings on the diamond, the Tigers hold a defensive efficiency of 71.9% (6th in professional baseball).

In his career, Jobe has allowed 40 base knocks while he has tallied 37 punch outs in 48 innings pitched. Jobe (4-1 win-loss mark in his career) is the owner of a 3.74 earned run average and has allowed 7.5 hits per nine innings. He has conceded a total of 20 ER's while earning a WHIP of 1.351 and being the owner of a FIP of 3.7. His K/BB ratio is 1.48 and he has faced 211 opposing hitters in his pro baseball career.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take San Francisco (+110)

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