Seattle Mariners vs Chicago Cubs Prediction, 6/22/2025 MLB Picks, Best Bets & Odds

Game: Seattle Mariners vs Chicago Cubs

Date: Sunday, June 22, 2025

Location: Wrigley Field in Chicago, IL

TV: Marquee

Odds/Point Spread: Seattle (+106) Chicago (-128)

The Seattle Mariners (37-36) are on their way to Wrigley Field on Sunday where they will take on the Chicago Cubs (45-29). The odds on this game have the Mariners at +106 and the Cubs are coming in at -128. The over/under comes in at 9. The men taking the mound are Logan Gilbert and Colin Rea.

The Mariners have hit 98 doubles as a unit and have knocked 91 balls out of the park. Seattle is slugging .394 and have been called out on strikes 649 times, while taking a walk on 265 occasions. As a team, the Seattle Mariners are notching 4.3 runs per game, which ranks them 13th in MLB. They have accounted for 306 runs batted in in addition to 600 hits for the year, and their team batting average is at .242. They have a total of 317 runs scored while holding a team OBP of .322.

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Their strikeout to walk ratio is 2.67 and their pitching staff has a team WHIP of 1.28. Mariners pitchers have surrendered 84 long balls and 315 runs (18th in baseball). Seattle has yielded 625 hits (8.5 per 9 innings) and 284 earned runs. The Mariners have an ERA of 3.87 this season (15th in the league), and the staff has struck out 596 hitters. They have walked 223 opposing hitters and their FIP comes in at 4.05 as a unit on the campaign.

The Mariners have sent 245 relief pitchers to the mound for the year. The relief pitchers have inherited 59 runners over the course of the season with 25.4% of those players ended up scoring. They have compiled 19 saves over the course of the season and have blown 12 of 31 save opportunities. The Mariners bullpen have accumulated a save rate of 61.3% and have come into the game in 65 save situations. The relief pitchers have 34 holds on the year (27th in the league). Mariners bullpen pitchers have stepped onto the hill with runners on 52 times and also have had 96 appearances in high leverage situations.

The San Francisco Giants have a total of 1,983 putouts over the course of the season, as well as 637 assists and 28 errors. Their fielding percentage is at .989 which has them sitting 3rd in baseball, and they have turned 63 double plays. The Mariners have transformed 70.0% of baseballs in play into outs out of 5,949 innings on the field, which ranks them 16th in baseball.

Gilbert (42-32 win-loss mark in his career) holds a FIP of 3.50 while he has faced 2,978 opposing hitters in the major leagues. He has surrendered 620 hits (7.5 hits per nine innings) and has had 157 walks. His earned run average is 3.56 (292 ER's allowed) and he has a WHIP of 1.051. Gilbert has pitched in 739 innings and has totaled 765 strikeouts during his MLB career.

Chicago has accumulated 102 home runs on the campaign to go along with 389 runs batted in. They have notched 133 two-baggers, while walking 260 times and racking up 397 runs. The Chicago Cubs are sitting with a team OBP of .324 and a team batting average of .254 on the campaign. The Cubs hold a team SLG% of .437 and they average 5.36 runs per outing (2nd in baseball). They have struck out on 588 occasions (21st in the league) and have 649 base hits.

The Cubs have a WHIP of 1.230 and have a FIP of 3.92 as a staff so far this year. They are sitting at 16th in the league as a staff in total hits relinquished with 607. The Chicago pitching staff have surrendered 291 runs for the year while holding a team ERA of 3.62 (267 earned runs relinquished). They currently have a strikeout to walk ratio of 7.80 (573 strikeouts vs 209 bases on balls). They have conceded 78 dingers and they concede 3.95 runs per 9 innings (10th in the league).

Chicago has had relief pitchers step onto the mound in 26 save opportunities and they have tallied 18 saves. They are ranked 9th in the league with a save rate of 69.2%, and they have sent 249 relief pitchers to the mound so far this season. Their bullpen pitchers have stepped onto the mound 88 times in high leverage situations and on 55 occasions with runners on. Chicago relievers have an inherited score rate of 31.1% out of their 74 inherited runners. With 77 save situations, the Cubs have recorded 49 holds and also 8 blown saves.

The Chicago Cubs have gotten 66 double plays and own a fielding percentage of .988 (6th in professional baseball). The Cubs have racked up 640 assists, 31 errors and have a total of 1,991 putouts on the campaign. In 5,973 innings on the diamond, the Cubs have accumulated a defensive efficiency of 70.7% (11th in the majors).

Rea (30-22 career win-loss mark) has earned a 4.48 ERA and has conceded 8.8 hits per nine innings. He has a strikeout to walk ratio of 2.68 and he has faced 2,189 opposing hitters in his MLB career. He has given up a total of 256 ER's while earning a WHIP of 1.284 and having a FIP of 4.4. So far in his pro baseball career, Rea has surrendered 504 base hits while he has tallied 418 punch outs in 514 innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Seattle (+106)

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