Seattle Mariners vs Houston Astros Prediction, 5/24/2025 MLB Picks, Best Bets & Odds

Game: Seattle Mariners vs Houston Astros

Date: Saturday, May 24, 2025

Location: Daikin Park in Houston, TX

TV: Space City Home Network

Odds/Point Spread: Seattle (-275) Houston (+220)

The Houston Astros (25-24) will try to defeat the Seattle Mariners (28-20) at Daikin Park on Saturday. The moneyline on this contest has Seattle at -275 while Houston is at +220. The over/under is 8.5. The pitchers expected to start will be Bryan Woo and Framber Valdez.

As a unit, the Seattle Mariners are earning 4.7 runs per game, which has them sitting at 8th in MLB. They have notched a total of 227 runs and hold an OBP of .324. The Mariners have accrued 63 doubles as a team and have hit 66 baseballs out of the park. They have earned 219 runs batted in and 382 hits this year, while their batting average is at .236. Seattle is slugging .399 and have been called out on strikes 423 times, while taking a walk on 191 occasions.

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The Mariners hold a team earned run average of 3.62 this season (11th in baseball), and the staff has struck out 398 batters. Mariners pitchers have yielded 47 home runs and 200 runs (13th in the league). Their pitching staff has walked 153 players from the other team and their FIP is 3.79 as a unit on the season. Seattle has allowed 414 base knocks (8.5 per 9 innings) in addition to 176 earned runs. They have accumulated a K/BB ratio of 2.60 and the pitching staff has earned a collective WHIP of 1.30.

The Mariners relief pitchers have a save percentage of 68.0% and have come into the game in 52 save situations. The relief pitchers have inherited 44 runners on the campaign with 27.3% of those runners crossed home plate. Mariners bullpen pitchers have entered the contest with players on base 39 times and also have had 70 appearances in high leverage situations. The Mariners have sent 169 relievers to the hill this season. The relief pitchers have accumulated 27 holds this year (19th in MLB). They have recorded 17 saves on the year and have blown 8 of their 25 save opportunities.

The Mariners have transformed 69.6% of baseballs in play into outs in their 3,939 innings, which has them sitting at 18th in MLB. The San Francisco Giants have earned a total of 1,313 putouts thus far, in addition to 425 assists and 20 errors. Their fielding percentage is at .989 which puts them in 6th in baseball, and they have turned 35 double plays.

Woo (18-9 career record) holds a FIP of 3.23 while going up against 1,065 hitters in the major leagues. He has allowed 213 hits (7.2 hits per 9 innings) with 52 free passes. His ERA is 3.28 (97 earned runs allowed) and he has a career WHIP of 0.995. Woo has thrown 266 frames and has earned 249 strikeouts during his pro baseball career.

The Astros hold a team SLG% of .378 and they score 3.98 runs per contest (23rd in the league). They have recorded 69 two-baggers, while getting a free base 154 times as well as notching 195 runs. Houston has accounted for 45 home runs so far this season to go along with 186 runs batted in. They have struck out on 383 occasions (21st in baseball) and have a total of 399 base hits. The Houston Astros are sitting with an on-base percentage of .317 in addition to a team batting average of .246 on the year.

The Astros are sitting with a team WHIP of 1.137 with a FIP of 3.56 as a unit on the season. They are sitting at 3rd in the league as a staff in total hits given up with 337. The Houston pitching staff have yielded 179 runs so far this season while having an ERA of 3.48 (166 earned runs yielded). Their K/BB ratio is 9.30 (445 strikeouts against 151 walks). They have allowed 46 long balls and they allow 3.75 runs per 9 innings (6th in the league).

Houston relievers hold an inherited score percentage of 30.8% out of their 52 inherited runners. Their relievers have stepped onto the mound 38 times in high leverage situations in addition to 35 occasions with runners on base. Sitting with 47 save situations, the Astros have compiled 29 holds and also 5 blown saves. They are currently ranked 4th in the league holding a save percentage of 72.2%, and they have dispatched 151 relievers to the mound for the season. Houston has had relief pitchers enter the game in 18 save chances and they have come away with 13 saves.

Out of their 3,864 innings on the diamond, the Astros have earned a defensive efficiency of 72.5% (4th in professional baseball). The Houston Astros have gotten 26 double plays and hold a fielding percentage of .987 (10th in MLB). The Astros have 363 assists, 22 errors and have amassed 1,288 putouts on the campaign.

Thus far in his career, Valdez has allowed 793 base hits while he has totaled 925 punch outs in 951 frames. Valdez (71-45 career mark) has earned a 3.32 earned run average and has surrendered 7.5 hits per 9 innings. He has allowed 351 earned runs while earning a WHIP of 1.191 and being the owner of a FIP of 3.3. He has a K/BB ratio of 2.72 and he has faced 3,934 batters in his MLB career.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Houston (+220)

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