Seattle Mariners vs Kansas City Royals Prediction, 9/17/2025 MLB Picks, Best Bets & Odds
Game: Seattle Mariners vs Kansas City Royals
Date: Wednesday, September 17, 2025
Location: Kauffman Stadium in Kansas City, MO
TV: FanDuel Sports Network Kansas City
Odds/Point Spread: Seattle (-196) Kansas City (+162)
The Kansas City Royals (75-75) welcome the Seattle Mariners (82-68) at Kauffman Stadium on Wednesday. The moneyline on this contest has Seattle at -196 while Kansas City is coming in at +162. The total has been set at 8. The starting pitchers will be Bryce Miller and Cole Ragans.


Seattle has a slugging rate of .416 and have struck out 1,329 times, while being walked on 509 occasions. They have recorded 676 runs batted in in addition to 1,242 base knocks this season, while their batting average comes in at .244. The Mariners have hit 215 doubles as a unit and have hit 216 baseballs out of the park. They have tallied 705 runs scored and have an OBP of .320. As a team, the Seattle Mariners are notching 4.7 runs per game, which has them sitting at 10th in MLB.
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The Mariners hold a team earned run average of 3.91 this year (14th in baseball), and their staff has rung up 1,315 batters. Mariners pitchers have allowed 179 home runs and 654 total runs (17th in MLB). They have walked 431 opposing hitters and their FIP comes in at 4.03 as a team for the season. Seattle has given up 1,244 base hits (8.3 per 9 innings) and 589 earned runs. They have earned a strikeout to walk ratio of 3.05 and the pitching staff has a collective WHIP of 1.24.
Mariners pitchers have stepped onto the hill with runners on base 124 times as well as having 205 appearances in high leverage situations. The relievers have tallied 85 holds on the season (14th in the league). The Mariners bullpen have accumulated a save percentage of 62.5% and have entered the game in 149 save situations. They have earned 40 saves on the season and have not converted 24 of 64 chances to get a save. The bullpen pitchers have inherited 134 base runners this season and 25.4% of those players ended up crossing the plate. The Mariners have sent 508 relievers to the hill on the year.
The San Francisco Giants have accumulated 4,067 putouts this year, in addition to 1,260 assists and 63 errors. Their fielding percentage sits at .988 which has them ranked 6th in professional baseball, and have accumulated 110 double plays. The Mariners have transformed 70.2% of baseballs in play into outs out of 12,201 innings, ranking them 14th in the majors.
Miller (24-20 win-loss mark in his career) has earned a FIP of 3.88 and he has gone up against 1,568 hitters in the major leagues. He has surrendered 330 hits (7.7 hits per nine innings) and has 100 free passes. His ERA is 3.94 (169 earned runs allowed) and his career WHIP is 1.113. Miller has taken the ball for 386 innings and is sitting with 354 strikeouts so far in his career.
Kansas City has a total of 144 home runs on the year to go along with 567 runs batted in. They have hit 263 doubles, while walking 397 times and scoring 577 runs. The Kansas City Royals have compiled an OBP of .305 and a team batting average of .244 on the campaign. The Royals hold a team slugging % of .391 and they average 3.85 runs per outing (28th in baseball). They have struck out on 1,015 occasions (30th in the league) and have earned 1,218 hits.
The Kansas City pitching staff have given up 589 runs this year while holding a team ERA of 3.72 (550 earned runs given up). They have given up 155 dingers and they surrender 3.99 runs per 9 innings (4th in the league). The Royals hold a team WHIP of 1.253 with a FIP of 4.00 as a squad so far this season. Their strikeout to walk ratio comes in at 7.90 (1,174 strikeouts vs 446 bases on balls). They are currently ranked 14th in baseball as a staff in total hits given up with 1,221.
Kansas City relievers hold an inherited score rate of 26.7% of 206 inherited runners. Their relief pitchers have taken the field 161 times in high leverage situations and also on 151 occasions with base runners. With 142 save situations, the Royals have earned 78 holds in addition to 19 blown saves. They sit at 4th in the league with a save percentage of 69.8%, and they have dispatched 505 relievers onto the diamond for the season. Kansas City has called on bullpen pitchers to enter the contest in 63 save chances and they have recorded 44 saves.
The Kansas City Royals have gotten 120 double plays and have earned a fielding percentage of .989 (4th in the majors). The Royals have accrued 1,326 assists, 57 errors and have earned 3,990 putouts this year. In 11,970 innings on the field, the Royals have a efficiency on defense of 70.6% (9th in baseball).
In his career, Ragans has allowed 306 base hits while he has tallied 439 strikeouts in 370 innings pitched. He has given up a total of 152 ER's while earning a WHIP of 1.204 and having a FIP of 3.6. He has a strikeout to walk ratio of 3.14 and he has faced 1,537 opposing hitters thus far in his career. Ragans (20-20 record in his career) has earned a 3.69 earned run average and has conceded 7.4 hits per 9 innings.
Who will win tonight's MLB game against the spread or moneyline?
Josh Schonwald's Pick: Take Kansas City (+162)
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Additional Resources:
Kansas City Royals - Twitter
Seattle Mariners - Twitter