St. Louis Cardinals vs Chicago White Sox Prediction, 6/19/2025 MLB Picks, Best Bets & Odds
Game: St. Louis Cardinals vs Chicago White Sox
Date: Thursday, June 19, 2025
Location: Rate Field in Chicago, IL
TV: Chicago Sports Network
Odds/Point Spread: St. Louis (-150) Chicago (+125)
Rate Field is where the Chicago White Sox (23-50) will take on the St. Louis Cardinals (38-35) on Thursday. The line on this matchup has the Cardinals at -150 and the White Sox are sitting at +125. The total is 8. The expected starting pitchers will be Erick Fedde and Adrian Houser.


As a squad, the St. Louis Cardinals are compiling 4.7 runs/g, which is 9th in baseball. They have earned a total of 340 runs and have an OBP of .328. The Cardinals have tallied 127 doubles as a unit and have hit 68 baseballs out of the park. They have tallied 322 RBI's in addition to 637 hits this season, while their batting average is sitting at .257. St. Louis has a slugging % of .393 and have struck out 567 times, while drawing a walk on 233 occasions.
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They have earned a K/BB ratio of 2.69 and their pitching staff has earned a collective WHIP of 1.27. Cardinals pitchers have given up 59 long balls and also 312 runs in total (19th in MLB). St. Louis has surrendered 629 base hits (8.8 per 9 innings) as well as 285 earned runs. The Cardinals have a team earned run average of 3.97 this season (20th in baseball), and the staff has struck out 521 batters. They have walked 194 players from the other team and their FIP is 3.65 as a team so far this season.
The Cardinals have dispatched 217 relievers to the hill so far this year. The relief pitchers have inherited 94 runners for the year with 36.2% of those players crossed home plate. They have compiled 17 saves so far this year and have not converted 11 of 28 chances to get a save. The Cardinals bullpen have a save rate of 60.7% and have entered the game in 75 save situations. The bullpen have racked up 44 holds so far this year (15th in MLB). Cardinals pitchers have come into the game with runners on base 72 times in addition to having 82 appearances in high leverage situations.
The St. Louis Cardinals have amassed 1,940 putouts this season, as well as 707 assists and 27 errors. Their fielding percentage is holding at .990 which ranks 2nd in baseball, and they have turned 54 double plays. The Cardinals have turned 69.6% of balls in play into outs out of their 5,820 innings on the diamond, ranking them 19th in the majors.
Fedde has taken the mound for 710 innings and has totaled 557 punch outs in his career. His earned run average is 4.69 (370 earned runs allowed) and his WHIP is 1.407. He has conceded 722 hits (9.1 hits per 9 innings) and has had 277 free passes. Fedde (33-48 career record) sits with a FIP of 4.62 while going up against 3,067 hitters in the majors.
Chicago is sitting with 55 home runs this season as well as 240 runs batted in. They have tallied 113 two-baggers, while getting a free base 235 times and putting up 250 runs. The Chicago White Sox hold an on-base percentage of .293 as well as a team batting average of .222 this season. The White Sox have a SLG% of .342 and they average 3.42 runs per game (28th in baseball). They have been called out on strikes on 633 occasions (10th in the league) and have earned a total of 529 hits.
The White Sox have a WHIP of 1.406 and are the owners of a FIP of 4.48 as a staff on the year. They are sitting at 19th in the league as a staff in total hits allowed with 616. The Chicago pitching staff have relinquished 322 runs over the course of the season while holding an ERA of 4.23 (296 earned runs given up). Their strikeout to walk ratio is 7.50 (526 strikeouts vs 270 walks). They have yielded 77 home runs and they allow 4.60 runs per 9 innings (23rd in the league).
Chicago relievers have an inherited score rate of 28.0% out of 100 inherited base runners. Their relief pitchers have stepped onto the hill 66 times in high leverage situations in addition to 70 occasions with runners on base. With 54 save situations, the White Sox have compiled 35 holds and 12 blown saves. They are currently ranked 30th in MLB with a save rate of 36.8%, and they have sent 233 relief pitchers to the hill this season. Chicago has had bullpen pitchers enter the contest in 19 save chances and they have tallied 7 saves.
In 5,673 innings on the field, the White Sox are sitting with a efficiency on defense of 69.2% (21st in pro baseball). The Chicago White Sox have gotten 61 double plays and own a fielding percentage of .982 (28th in pro baseball). The White Sox have 591 assists, 46 errors and have amassed 1,891 putouts so far this season.
During his MLB career, Houser has allowed 619 base hits while he has totaled 506 strikeouts in 637 frames. He has allowed 292 earned runs while earning a WHIP of 1.370 and having a FIP of 4.1. His K/BB ratio is 1.99 and he has gone up against 2,736 hitters in his career. Houser (34-41 career mark) holds a 4.12 ERA and has surrendered 8.7 hits per 9 innings.
Who will win tonight's MLB game against the spread or moneyline?
Tony Sink's Pick: Take St. Louis (-150)
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Additional Resources:
Chicago White Sox - Twitter
St. Louis Cardinals - Twitter