St. Louis Cardinals vs Cincinnati Reds Prediction, 5/1/2025 MLB Picks, Best Bets & Odds
Game: St. Louis Cardinals vs Cincinnati Reds
Date: Thursday, May 1, 2025
Location: Great American Ball Park in Cincinnati, OH
TV: FanDuel Sports Network Ohio
Odds/Point Spread: St. Louis (+132) Cincinnati (-160)
The St. Louis Cardinals (12-17) are hitting the road to Great American Ball Park on Thursday where they will attempt to beat the Cincinnati Reds (16-13). The line on this matchup has St. Louis at +132 and Cincinnati is priced at -160. The total is set at 9. The starting pitchers will be Matthew Liberatore and Hunter Greene.


As a team, the St. Louis Cardinals are putting up 4.5 runs per game, which has them at 13th in MLB. They have accounted for 131 runs and have an OBP of .333. The Cardinals have hit 61 two-baggers as a team and have smacked 24 baseballs out of the park. They have tallied 124 RBI's and 264 base knocks over the course of the season, while their team batting average sits at .263. St. Louis is slugging .397 and have been rung up 228 times, while drawing a walk on 102 occasions.
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The Cardinals have an ERA of 4.33 for the season (22nd in the league), and they have rung up 197 batters. Cardinals pitchers have conceded 24 home runs and also 135 runs in total (20th in the league). They have walked 89 opposing players and their FIP is 3.88 as a unit on the season. St. Louis has surrendered 235 base hits (8.2 per 9 innings) and 124 earned runs. Their strikeout to walk ratio sits at 2.21 and the pitching staff sits with a WHIP of 1.26.
Cardinals pitchers have entered the contest with runners on base 32 times in addition to having 41 appearances in high leverage situations. The bullpen have 19 holds so far this year (13th in MLB). The Cardinals relievers have a save percentage of 46.2% and stepped onto the hill in 32 save situations. They have earned 6 saves for the year and have not converted 7 out of their 13 chances to save the game. The relief pitchers have inherited 36 base runners this season with 44.4% of them ended up crossing the plate. The Cardinals have dispatched 95 relievers to the hill on the campaign.
The St. Louis Cardinals are sitting with 773 putouts this year, as well as 295 assists and 11 errors. Their fielding percentage is at .990 which is 2nd in MLB, and have a total of 19 double plays. The Cardinals have converted 71.5% of balls hit into play into outs in their 2,319 innings, which has them sitting at 7th in MLB.
Liberatore has pitched in 213 frames and has 178 strikeouts during his MLB career. Liberatore (10-14 career record) is the owner of a FIP of 4.66 while facing 915 opposing hitters in the major leagues. His earned run average is 4.73 (112 earned runs allowed) and his WHIP is 1.361. He has conceded 217 base hits (9.2 hits per 9 innings) with 73 free passes.
The Reds hold a team SLG% of .408 and they are scoring 5.28 runs per contest (4th in baseball). They have put up 48 two-baggers, while walking 108 times and earning 153 runs. Cincinnati is sitting with 33 home runs on the year to go along with 147 runs batted in. They have struck out on 247 occasions (13th in MLB) and have tallied 250 base hits. The Cincinnati Reds have accounted for an OBP of .334 as well as a batting average of .254 over the course of the season.
The Reds have a WHIP of 1.089 with a FIP of 4.14 as a pitching staff this year. They are currently ranked 2nd in the league as a pitching staff in total hits given up with 196. The Cincinnati pitching staff have given up 110 runs this year while holding a team ERA of 3.37 (96 earned runs yielded). They currently have a K/BB ratio of 8.30 (235 strikeouts vs 83 bases on balls). They have yielded 36 homers and they surrender 3.87 runs per 9 innings (9th in baseball).
Cincinnati bullpen pitchers hold an inherited score percentage of 20.6% out of 34 inherited runners. Their bullpen pitchers have stepped onto the mound 29 times in high leverage situations in addition to 22 occasions with runners on base. Sitting with 40 save situations, the Reds have accumulated 25 holds in addition to 4 blown saves. They are ranked 11th in baseball holding a save percentage of 71.4%, and they have sent 95 bullpen pitchers to the mound on the campaign. Cincinnati has had relief pitchers step onto the mound in 14 save opportunities and they have recorded 10 saves.
The Cincinnati Reds have gotten 13 double plays and have earned a fielding percentage of .983 (21st in professional baseball). The Reds have accrued 206 assists, 17 errors and have a total of 769 putouts so far this year. In their 2,307 innings on the field, the Reds are sitting with a efficiency on defense of 75.0% (1st in the majors).
Greene (21-27 record in his career) has earned a 3.80 ERA and has allowed 7.1 hits per nine innings. His K/BB ratio is 3.32 and he has gone up against 1,783 batters so far in his career. He has surrendered a total of 179 earned runs while holding a WHIP of 1.167 and a FIP of 3.7. So far in his pro baseball career, Greene has allowed 336 hits while earning 528 punch outs in 424 frames.
Who will win tonight's MLB game against the spread or moneyline?
Tony Sink's Pick: Take Cincinnati (-160)
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Additional Resources:
Cincinnati Reds - Twitter
St. Louis Cardinals - Twitter