St. Louis Cardinals vs Cincinnati Reds Prediction, 8/31/2025 MLB Picks, Best Bets & Odds
Game: St. Louis Cardinals vs Cincinnati Reds
Date: Sunday, August 31, 2025
Location: Great American Ball Park in Cincinnati, OH
TV: FanDuel Sports Network Ohio
Odds/Point Spread: St. Louis (+110) Cincinnati (-130)
The Cincinnati Reds (68-66) will take on the St. Louis Cardinals (66-69) at Great American Ball Park on Sunday. The odds on this game have St. Louis at +110 and Cincinnati is coming in at -130. The over/under has been set at 9. The pitchers taking the mound are Andre Pallante and Brady Singer.


The Cardinals have compiled 223 doubles as a team and have hit 127 balls out of the park. St. Louis has a slugging rate of .383 and have struck out 1,066 times, while drawing a walk on 407 occasions. As a team, the St. Louis Cardinals are putting up 4.4 runs per game, which has them sitting at 16th in MLB. They have accrued 560 RBI's in addition to 1,123 base knocks this year, and their team batting average is sitting at .248. They are sitting with 588 runs scored while holding a team on-base percentage of .316.
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They have earned a strikeout to walk ratio of 2.68 and the pitching staff has earned a collective WHIP of 1.30. Cardinals pitchers have given up 136 home runs and 622 runs in total (23rd in the league). St. Louis has conceded 1,178 hits (8.9 per 9 innings) and 567 earned runs. The Cardinals are sitting with a team earned run average of 4.28 for the year (21st in baseball), and the staff has struck out 999 batters. They have walked 373 opposing hitters and their FIP is 3.97 as a team for the year.
The Cardinals have sent 398 relievers to the hill so far this season. The relievers have inherited 176 base runners on the season and 33.5% of those players crossed home plate. They have 33 saves so far this year and have blown 18 of their 51 save opportunities. The Cardinals relief pitchers have a save percentage of 64.7% and have come into the game in 129 save situations. The relief pitchers have tallied 75 holds on the year (13th in baseball). Cardinals pitchers have entered the game with runners on base 126 times as well as having 123 appearances in high leverage situations.
The St. Louis Cardinals have earned a total of 3,548 putouts on the year, in addition to 1,287 assists and 66 errors. Their fielding rate is holding at .987 which ranks 15th in pro baseball, and have earned 103 double plays. The Cardinals have turned 69.1% of balls in play into outs in their 10,644 innings on the field, which has them sitting 23rd in professional baseball.
Pallante (24-26 win-loss record in his career) sits with a FIP of 4.25 while he has gone up against 1,874 opposing hitters in the majors. He has given up 449 base knocks (9.3 hits per nine innings) and has 166 free passes. His ERA is 4.31 (209 earned runs allowed) and his career WHIP is 1.410. Pallante has pitched in 436 innings and has 305 K's so far in his career.
The Reds have a SLG% of .388 and they tally 4.46 runs per contest (15th in MLB). They have hit 212 doubles, while taking a walk 435 times and scoring 597 runs. Cincinnati has hit 130 home runs on the campaign as well as 562 runs batted in. They have struck out on 1,165 occasions (10th in baseball) and have accounted for 1,107 base hits. The Cincinnati Reds are sitting with an on-base percentage of .316 in addition to a batting average of .246 on the season.
The Cincinnati pitching staff have conceded 563 runs so far this year while holding an ERA of 3.85 (506 earned runs given up). They have yielded 150 HR's and they allow 4.28 runs per 9 innings (14th in MLB). The Reds have a team WHIP of 1.240 and have a FIP of 4.05 as a pitching staff on the season. Their K/BB ratio sits at 8.50 (1,125 strikeouts vs 418 bases on balls). They are sitting at 7th in baseball as a pitching staff in total hits given up with 1,050.
Cincinnati has had relief pitchers take the mound in 50 save chances and they have tallied 31 saves. They sit at 20th in baseball holding a save rate of 62.0%, and they have sent 457 bullpen pitchers to the mound for the season. Their relievers have stepped onto the hill 135 times in high leverage situations in addition to 123 occasions with base runners. Cincinnati relievers hold an inherited score rate of 32.1% of 184 inherited base runners. With 135 save situations, the Reds have 83 holds in addition to 19 blown saves.
The Cincinnati Reds have turned 85 double plays and own a fielding percentage of .984 (26th in pro baseball). The Reds have recorded 1,024 assists, 76 errors and have a total of 3,554 putouts for the year. Out of their 10,662 innings on the field, the Reds have earned a defensive efficiency of 70.8% (8th in the majors).
Singer (47-53 win-loss record in his career) has earned a 4.25 ERA while allowing 9.0 hits per 9 innings. His K/BB ratio is 2.92 and he has faced 3,515 batters during his career. He has conceded 388 earned runs while earning a WHIP of 1.318 and having a FIP of 4.2. In his career, Singer has surrendered 818 base hits while he has totaled 777 strikeouts in 822 innings.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take St. Louis (+110)
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Additional Resources:
Cincinnati Reds - Twitter
St. Louis Cardinals - Twitter