Tampa Bay Rays vs Baltimore Orioles Prediction, 9/25/2025 MLB Picks, Best Bets & Odds
Game: Tampa Bay Rays vs Baltimore Orioles
Date: Thursday, September 25, 2025
Location: Oriole Park at Camden Yards in Baltimore, MD
TV: MASN
Odds/Point Spread: Tampa Bay (-150) Baltimore (+125)
Oriole Park at Camden Yards is the location where the Baltimore Orioles (74-83) will attempt to defeat the Tampa Bay Rays (76-81) on Thursday. The moneyline on this contest has Tampa Bay at -150 and Baltimore is sitting at +125. The total comes in at 9. The starting pitchers will be Drew Rasmussen and Cade Povich.


As a squad, the Tampa Bay Rays are notching 4.4 runs per outing, which has them sitting at 16th in MLB. They are sitting with 696 runs scored and hold an on-base percentage of .313. The Rays have earned 235 two-baggers as a unit and have hit 177 baseballs out of the stadium. They have tallied 663 runs batted in as well as 1,326 base knocks this year, and their average at the plate sits at .250. Tampa Bay is slugging .401 and have been called out on strikes 1,346 times, while being walked on 452 occasions.
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The Rays have compiled a team earned run average of 3.86 so far this year (9th in MLB), and the staff has struck out 1,369 batters. Rays pitchers have surrendered 196 home runs and also 653 runs (10th in baseball). They have walked 455 hitters and their FIP sits at 4.13 as a unit on the year. Tampa Bay has given up 1,232 hits (8.0 per 9 innings) and 597 earned runs. They have earned a K/BB ratio of 3.01 and their pitching staff sits with a WHIP of 1.21.
The Rays relievers have a save percentage of 55.6% and have entered the game in 153 save situations. The bullpen pitchers have inherited 161 base runners over the course of the season with 31.1% of them ended up crossing the plate. Rays relief pitchers have stepped onto the hill with runners on 109 times and also have had 154 appearances in high leverage situations. The Rays have sent 504 relief pitchers to the mound so far this year. The relief pitchers are sitting with 87 holds for the year (16th in MLB). They have accumulated 35 saves so far this season and have blown 28 of 63 save opportunities.
The Rays have converted 70.6% of balls in play into outs out of their 12,513 innings on the field, which has them ranked 9th in MLB. The Tampa Bay Rays have a total of 4,171 putouts this season, in addition to 1,380 assists and 77 errors. Their fielding rate sits at .986 which puts them in 14th in the majors, and have a total of 142 double plays.
Rasmussen has taken the ball for 457 innings and has racked up 425 punch outs in his pro baseball career. Rasmussen (30-17 career win-loss record) is the owner of a FIP of 2.87 while he has faced 1,829 batters during his time in the majors. His ERA is 2.91 (148 earned runs allowed) and he has a WHIP of 1.065. He has allowed 370 base hits (7.3 hits per nine innings) and has had 117 walks.
The Baltimore Orioles have an on-base percentage of .305 and a team batting average of .237 for the season. They have struck out on 1,406 occasions (4th in the league) and have earned 1,246 hits. Baltimore has hit 183 HRs over the course of the season to go along with 629 RBIs. The Orioles have a team SLG% of .395 and they average 4.22 runs per contest (22nd in baseball). They have 248 two-baggers, while taking a walk 464 times and racking up 662 runs.
The Baltimore pitching staff have conceded 760 runs this season while having a team ERA of 4.58 (707 earned runs conceded). They have given up 207 homers and they allow 4.92 runs per 9 innings (24th in MLB). The Orioles have a WHIP of 1.362 and have a FIP of 4.40 as a team so far this season. They have earned a K/BB ratio of 8.50 (1,308 strikeouts vs 509 walks). They are currently ranked 25th in baseball as a pitching staff in total hits allowed with 1,385.
With 167 save situations, the Orioles have 105 holds in addition to 20 blown saves. Baltimore has called on relievers to take the mound in 58 save opportunities and they have converted 38 saves. Their relievers have stepped onto the hill 167 times in high leverage situations and on 151 occasions with runners on base. Baltimore bullpen pitchers hold an inherited score percentage of 26.7% out of their 210 inherited runners. They sit at 8th in MLB with a save rate of 65.5%, and they have dispatched 526 relief pitchers onto the diamond on the season.
In their 12,516 innings played, the Orioles have accumulated a efficiency on defense of 68.5% (26th in the majors). The Baltimore Orioles have gotten 117 double plays and own a fielding percentage of .985 (18th in professional baseball). The Orioles have accrued 1,371 assists, 85 errors and have earned a total of 4,172 putouts during this campaign.
In his pro baseball career, Povich has allowed 195 base knocks while tallying 183 K's in 185 innings pitched. Povich (6-17 career mark) has earned a 5.15 ERA and has given up 9.5 hits per 9 innings. He has allowed 106 ER's while earning a WHIP of 1.456 and having a FIP of 5.1. He has a strikeout to walk ratio of 2.44 and he has faced 814 hitters during his career.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take Baltimore (+125)
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Additional Resources:
Baltimore Orioles - Twitter
Tampa Bay Rays - Twitter