Tampa Bay Rays vs Chicago Cubs Prediction, 9/14/2025 MLB Picks, Best Bets & Odds

Game: Tampa Bay Rays vs Chicago Cubs

Date: Sunday, September 14, 2025

Location: Wrigley Field in Chicago, IL

TV: Marquee

Odds/Point Spread: Tampa Bay (+172) Chicago (-210)

Wrigley Field is the location where the Chicago Cubs (83-63) will attempt to defeat the Tampa Bay Rays (72-74) on Sunday. The moneyline on this contest has Tampa Bay at +172 while Chicago is priced at -210. The total is set at 8.5. The starting pitchers are Adrian Houser and Shota Imanaga.

Tampa Bay is slugging .403 and have struck out 1,246 times, while drawing a walk on 418 occasions. They have earned 623 RBI's and 1,239 base knocks on the season, and their team batting average is at .252. The Rays have accrued 219 two-baggers as a team and have hit 166 baseballs out of the park. They have accumulated 655 runs and hold an OBP of .313. As a team, the Tampa Bay Rays are scoring 4.5 runs per game, which has them at 14th in baseball.

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The Rays have an ERA of 3.88 on the campaign (12th in MLB), and the staff has rung up 1,279 batters. Rays pitchers have conceded 187 long balls and also 604 total runs (9th in the league). They have walked 419 opposing players and their FIP comes in at 4.16 as a unit on the campaign. Tampa Bay has relinquished 1,141 hits (7.9 per 9 innings) as well as 557 earned runs. They have earned a strikeout to walk ratio of 3.05 and the pitching staff has a collective WHIP of 1.21.

Rays bullpen pitchers have gone to the mound with opponents on base 102 times in addition to having 139 appearances in high leverage situations. The relievers are sitting with 81 holds so far this year (16th in MLB). The Rays relief pitchers have a save rate of 56.9% and have entered the game in 141 save situations. They have accumulated 33 saves on the year and have not converted 25 of their 58 save chances. The bullpen pitchers have inherited 150 runners on the campaign and 32.0% of those players ended up crossing the plate. The Rays have dispatched 465 relievers to the hill this year.

The Rays have turned 70.8% of balls hit into play into outs out of 11,631 innings on the diamond, which has them sitting 6th in baseball. The Tampa Bay Rays are sitting with 3,877 putouts this year, as well as 1,274 assists and 69 errors. Their fielding percentage sits at .987 which is 12th in MLB, and they have turned 132 double plays.

Houser has thrown 715 innings and is sitting with 567 punch outs during his career. Houser (40-43 win-loss mark in his career) has earned a FIP of 3.99 while going up against 3,061 opposing batters during his time in the majors. His ERA is 4.05 (322 ER's allowed) and his career WHIP is 1.360. He has conceded 697 hits (8.8 hits per nine innings) and has had 276 free passes.

Chicago has accumulated 196 home runs so far this season as well as 696 runs batted in. They have hit 239 doubles, while walking 500 times as well as earning 713 runs. The Chicago Cubs have an OBP of .319 as well as a team batting average of .248 this year. The Cubs have a SLG% of .425 and they tally 4.88 runs per game (8th in baseball). They have been called out on strikes on 1,140 instances (27th in baseball) and have tallied 1,230 hits.

The Cubs hold a team WHIP of 1.191 and have a FIP of 4.18 as a squad on the year. Their strikeout to walk ratio sits at 7.80 (1,119 strikeouts vs 370 walks). They rank 10th in MLB as a staff in total hits allowed with 1,172. They have given up 179 homers and they surrender 4.12 runs per 9 innings (6th in the league). The Chicago pitching staff have surrendered 593 runs for the year while having an ERA of 3.86 (555 earned runs yielded).

With 157 save situations, the Cubs have amassed 99 holds and also 17 blown saves. Chicago has called on relief pitchers to enter the contest in 55 save chances and they have tallied 38 saves. Their relievers have taken the field 146 times in high leverage situations and on 94 occasions with runners on base. Chicago relievers have an inherited score rate of 32.8% of 131 inherited base runners. They sit at 5th in baseball with a save percentage of 69.1%, and they have sent 474 bullpen pitchers to the hill on the year.

In 11,655 innings played, the Cubs have accumulated a efficiency on defense of 71.6% (3rd in pro baseball). The Chicago Cubs have gotten 113 double plays and have a fielding percentage of .989 (5th in professional baseball). The Cubs have accrued 1,225 assists, 57 errors and have amassed 3,885 putouts this season.

In his MLB career, Imanaga has allowed 246 hits while he has tallied 275 strikeouts in 302 innings. Imanaga (24-10 career mark) holds a 3.04 earned run average while conceding 7.3 hits per nine innings. He has surrendered 102 earned runs while earning a WHIP of 0.983 and a FIP of 3.0. His K/BB ratio is 5.39 and he has gone up against 1,193 batters during his MLB career.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Tampa Bay (+172)

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