Tampa Bay Rays vs Chicago White Sox Prediction, 9/11/2025 MLB Picks, Best Bets & Odds

Game: Tampa Bay Rays vs Chicago White Sox

Date: Thursday, September 11, 2025

Location: Rate Field in Chicago, IL

TV: Chicago Sports Network

Odds/Point Spread: Tampa Bay (-128) Chicago (+106)

Rate Field is where the Chicago White Sox (55-90) will take on the Tampa Bay Rays (72-72) on Thursday. The moneyline on this contest has the Rays at -128 and the White Sox are priced at +106. The betting total is set at 8. The expected starting pitchers will be Ian Seymour and Shane Smith.

As a team, the Tampa Bay Rays are scoring 4.5 runs per contest, which has them at 14th in baseball. They have tallied 649 runs scored and hold an on-base percentage of .313. The Rays have accumulated 218 two-baggers as a squad and have knocked 163 baseballs out of the stadium. They have tallied 617 RBI's as well as 1,224 base knocks over the course of the season, while their batting average is sitting at .252. Tampa Bay owns a slugging percentage of .403 and have struck out 1,228 times, while being walked on 409 occasions.

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They have a K/BB ratio of 3.07 and the pitching staff has a collective WHIP of 1.20. Rays pitchers have yielded 186 home runs in addition to 593 runs in total (7th in the league). Tampa Bay has given up 1,126 hits (7.9 per 9 innings) and 546 earned runs. The Rays have compiled a team ERA of 3.85 over the course of the season (9th in the league), and the staff has struck out 1,260 batters. Their pitching staff has walked 411 opposing hitters and their FIP sits at 4.17 as a team this season.

The Rays have sent 458 relief pitchers to the mound so far this season. The relievers have inherited 147 runners on the season with 32.0% of those runners ended up scoring. They have 33 saves on the season and have blown 25 of 58 save chances. The Rays relievers have accumulated a save rate of 56.9% and stepped onto the hill in 141 save situations. The relief pitchers have 81 holds on the season (16th in MLB). Rays bullpen pitchers have stepped onto the hill with runners on 99 times in addition to having 139 appearances in high leverage situations.

The Tampa Bay Rays have accounted for 3,829 putouts on the year, in addition to 1,260 assists and 69 errors. Their fielding percentage is holding steady at .987 which puts them in 12th in baseball, and they have turned 130 double plays. The Rays have converted 70.8% of balls hit into play into outs in their 11,487 innings, ranking them 5th in professional baseball.

Seymour has taken the hill for 37 innings and has earned 47 punch outs in his pro baseball career. Seymour (3-1 career mark) has earned a FIP of 2.87 and he has gone up against 156 hitters during his time in the major leagues. His ERA is 2.91 (12 ER's allowed) and he has a WHIP of 1.105. He has allowed 29 hits (7.0 hits per 9 innings) with 12 walks.

The Chicago White Sox have recorded an on-base percentage of .304 in addition to a team batting average of .235 for the season. They have been rung up on 1,207 occasions (15th in the league) and have earned a total of 1,138 base knocks. Chicago has tallied 149 HRs this year to go along with 566 RBIs. The White Sox have a SLG% of .378 and they are recording 4.04 runs per outing (26th in the league). They have 223 two-baggers, while walking 453 times as well as scoring 586 runs.

The White Sox are sitting with a team WHIP of 1.364 with a FIP of 4.46 as a squad on the campaign. They are sitting at 16th in baseball as a pitching staff in total hits allowed with 1,196. The Chicago pitching staff have relinquished 667 runs so far this year while having a team ERA of 4.24 (598 earned runs relinquished). They currently have a K/BB ratio of 8.00 (1,129 strikeouts vs 535 bases on balls). They have allowed 163 dingers and they surrender 4.73 runs per 9 innings (22nd in baseball).

Chicago has had relievers enter the contest in 43 save opportunities and they have come away with 22 saves. They are ranked 30th in the league with a save rate of 51.2%, and they have dispatched 468 relief pitchers onto the field for the year. Their relief pitchers have taken the field 134 times in high leverage situations and on 143 occasions with runners on base. Chicago bullpen pitchers have an inherited score rate of 32.1% out of their 209 inherited base runners. Sitting with 103 save situations, the White Sox have 60 holds and 21 blown saves.

The Chicago White Sox have gotten 114 double plays and have notched a fielding percentage of .981 (28th in baseball). The White Sox have recorded 1,151 assists, 95 errors and have a tally of 3,808 putouts so far this season. In their 11,424 innings played, the White Sox have a defensive efficiency of 69.7% (18th in professional baseball).

Smith (5-7 career record) has earned a 3.96 earned run average and has surrendered 7.1 hits per nine innings. He has a K/BB ratio of 2.27 and he has gone up against 530 hitters in his MLB career. He has given up a total of 55 earned runs while earning a WHIP of 1.199 and having a FIP of 3.9. So far in his MLB career, Smith has surrendered 98 base hits while accumulating 118 strikeouts in 125 frames.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Chicago (+106)

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