Boston Red Sox vs Houston Astros Prediction, 4/1/2026 MLB Picks, Best Bets & Odds
Game: Boston Red Sox vs Houston Astros
Date: Wednesday, April 1, 2026
Location: Daikin Park in Houston, TX
TV: Space City Home Network
Odds/Point Spread: Boston (+220) Houston (-275)
The Boston Red Sox (1-3) are traveling to Daikin Park on Wednesday where they will compete against the Houston Astros (3-2). The odds on this game have Boston at +220 and Houston is sitting at -275. The over/under is 8.5. The pitchers taking the mound will be Garrett Crochet and Mike Burrows.

The Red Sox have hit 8 two-baggers as a squad and have smacked 3 baseballs out of the stadium. Boston has a slugging percentage of .350 and have struck out 41 times, while drawing a walk on 16 occasions. As a squad, the Boston Red Sox are putting up 2.8 runs per contest, which is 25th in baseball. They have compiled 10 RBI's and 31 hits this season, and their team batting average sits at .226. They have accumulated 11 runs and hold an OBP of .316.
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They have accumulated a K/BB ratio of 2.44 and the pitching staff has a collective WHIP of 1.42. Red Sox pitchers have surrendered 7 home runs and also 17 runs in total (17th in the league). Boston has given up 34 base hits (8.7 per 9 innings) and also 15 earned runs. The Red Sox have compiled a team ERA of 3.82 on the year (15th in the league), and the staff has rung up 39 batters. Their pitching staff has walked 16 opposing batters and their FIP is 5.02 as a unit on the year.
The bullpen pitchers have inherited 4 base runners for the year and 25.0% of them ended up scoring. Red Sox bullpen pitchers have stepped onto the hill with players on base 5 times as well as having 6 appearances in high leverage situations. The Red Sox have sent 12 relievers to the hill this season. The relief pitchers are sitting with 2 holds over the course of the season (14th in MLB).
The Baltimore Orioles have accounted for 106 putouts at this point in the season, in addition to 28 assists and 2 errors. Their fielding percentage is holding steady at .985 which has them ranked 18th in professional baseball, and they have turned 3 double plays. The Red Sox have turned 69.2% of balls hit into play into outs out of their 318 innings, which has them sitting 23rd in MLB.
Crochet has pitched in 430 innings and has earned 557 strikeouts so far in his MLB career. Crochet (28-24 career win-loss record) sits with a FIP of 2.86 while he has gone up against 1,749 hitters during his time in the major leagues. His ERA is 2.91 (139 ER's allowed) and his career WHIP is 1.090. He has surrendered 348 base hits (7.3 hits per nine innings) and has 121 free passes.
The Astros hold a team slugging % of .435 and they are scoring 6.00 runs per game (5th in MLB). They have tallied 14 doubles, while walking 25 times as well as earning 30 runs. Houston has accounted for 5 home runs this season as well as 25 RBIs. They have been rung up on 43 occasions (8th in MLB) and have earned 44 base hits. The Houston Astros have a team on-base percentage of .365 and a batting average of .262 so far this season.
The Houston pitching staff have given up 26 runs this year while having an ERA of 5.20 (26 earned runs conceded). They have given up 9 long balls and they concede 5.20 runs per 9 innings (23rd in the league). The Astros have a team WHIP of 1.489 and have a FIP of 5.44 as a pitching staff on the season. They have earned a strikeout to walk ratio of 11.60 (58 strikeouts vs 30 walks). They come in at 25th in baseball as a pitching staff in total hits relinquished with 37.
They rank 3rd in baseball with a save percentage of 100.0%, and they have sent 16 relievers to the hill this season. Their relievers have stepped onto the mound 3 times in high leverage situations and on 7 occasions with runners on.
In 405 innings played, the Astros are sitting with a defensive efficiency of 71.1% (15th in baseball). The Houston Astros have turned 8 double plays and have notched a fielding percentage of 1.000 (4th in baseball). The Astros have 39 assists, no errors and are sitting with 135 putouts on the campaign.
Burrows (3-5 mark in his career) is the owner of a 4.14 earned run average and has conceded 8.5 hits per nine innings. His strikeout to walk ratio is 2.92 and he has gone up against 442 hitters during his MLB career. He has allowed 48 ER's while earning a WHIP of 1.294 and a FIP of 4.1. Thus far in his career, Burrows has given up 99 hits while he has accumulated 105 strikeouts in 104 innings.
Who will win tonight's MLB game against the spread or moneyline?
Josh Schonwald's Pick: Take Boston (+220)
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Additional Resources:
Houston Astros - Twitter
Boston Red Sox - Twitter
