Boston Red Sox vs St. Louis Cardinals Prediction, 4/12/2026 MLB Picks, Best Bets & Odds
Game: Boston Red Sox vs St. Louis Cardinals
Date: Sunday, April 12, 2026
Location: Busch Stadium in St. Louis, MO
TV: Cardinals.TV
Odds/Point Spread: Boston (+162) St. Louis (-196)
Busch Stadium is the location where the St. Louis Cardinals (8-5) will go up against the Boston Red Sox (4-9) on Sunday. The moneyline on this game has the Red Sox at +162 while the Cardinals are at -196. The over/under comes in at 8.5. The pitchers taking the mound are Brayan Bello and Andre Pallante.

As a team, the Boston Red Sox are knocking in 3.5 runs per outing, which has them at 24th in the league. They have earned a total of 46 runs while having a team OBP of .303. The Red Sox have hit 21 doubles as a unit and have smacked 9 balls out of the stadium. They have amassed 44 RBI's and 94 hits on the season, and their team batting average sits at .221. Boston has a slugging percentage of .344 and have been called out on strikes 121 times, while taking a walk on 44 occasions.
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They have a strikeout to walk ratio of 2.13 and the pitching staff holds a WHIP of 1.38. Red Sox pitchers have surrendered 13 long balls and 58 total runs (16th in the league). Boston has allowed 104 base hits (8.3 per 9 innings) and also 52 earned runs. The Red Sox hold a team ERA of 4.13 so far this season (21st in the league), and they have struck out 111 hitters. They have walked 52 opposing players and their FIP is 4.19 as a unit so far this year.
The Red Sox relief pitchers have recorded a save rate of 60.0% and stepped onto the hill in 12 save situations. They have 3 saves for the year and have not converted 2 of their 5 chances to get a save. The relief pitchers have inherited 18 base runners this year and 33.3% of those runners ended up scoring. Red Sox pitchers have come into the game with players on base 12 times and also have had 15 appearances in high leverage situations. The Red Sox have dispatched 43 relievers to the mound on the season. The relief pitchers have a total of 7 holds so far this year (18th in the league).
The Baltimore Orioles have a total of 340 putouts this year, in addition to 114 assists and 12 errors. Their fielding rate is at .974 which ranks 27th in pro baseball, and have accumulated 9 double plays. The Red Sox have turned 68.5% of baseballs in play into outs out of their 1,020 innings on the diamond, which has them sitting at 22nd in pro baseball.
Bello has taken the ball for 551 frames and has racked up 471 punch outs during his career. Bello (39-37 win-loss record in his career) sits with a FIP of 4.10 while he has gone up against 2,383 opposing hitters during his time in the major leagues. His earned run average is 4.16 (255 ER's allowed) and he has a WHIP of 1.377. He has surrendered 557 hits (9.1 hits per nine innings) and has 202 free passes.
St. Louis has accumulated 13 home runs on the year as well as 61 runs batted in. They have notched 17 two-baggers, while getting a free base 59 times as well as scoring 62 runs. The St. Louis Cardinals have an OBP of .329 and a team batting average of .228 so far this season. The Cardinals hold a slugging % of .359 and they have an average of 4.77 runs per contest (7th in the league). They have been called out on strikes on 108 instances (23rd in MLB) and have notched a total of 98 base hits.
The Cardinals have a WHIP of 1.449 with a FIP of 4.70 as a team on the campaign. Their strikeout to walk ratio sits at 6.20 (81 strikeouts against 53 free passes). They are sitting at 26th in baseball as a staff in total hits given up with 118. They have given up 13 dingers and they allow 4.88 runs per 9 innings (25th in MLB). The St. Louis pitching staff have surrendered 64 runs on the year while having an ERA of 4.65 (61 earned runs surrendered).
With 21 save situations, the Cardinals have compiled 13 holds and 2 blown saves. St. Louis has called on relievers to enter the contest in 7 save chances and they have come away with 5 saves. St. Louis bullpen pitchers have an inherited score percentage of 42.3% of 26 inherited base runners. Their relief pitchers have come in 21 times in high leverage situations and also on 17 occasions with runners on. They are ranked 14th in MLB holding a save rate of 71.4%, and they have sent 50 relievers to the hill for the year.
The St. Louis Cardinals have gotten 9 double plays and hold a fielding percentage of .986 (15th in pro baseball). The Cardinals have accrued 131 assists, 7 errors and have a tally of 354 putouts for the year. Out of their 1,062 innings on the diamond, the Cardinals have a defensive efficiency of 70.2% (15th in MLB).
So far in his career, Pallante has given up 478 base knocks while earning 326 K's in 470 innings. Pallante (25-29 career mark) has earned a 4.27 earned run average and has surrendered 9.2 hits per 9 innings. He has surrendered 223 earned runs while holding a WHIP of 1.415 and having a FIP of 4.2. His strikeout to walk ratio is 1.74 and he has faced 2,026 batters in his pro baseball career.
Who will win tonight's MLB game against the spread or moneyline?
Tony Sink's Pick: Take St. Louis (-196)
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Additional Resources:
St. Louis Cardinals - Twitter
Boston Red Sox - Twitter
