Milwaukee Brewers vs Philadelphia Phillies Prediction, 9/23/2026 MLB Picks, Best Bets & Odds

Game: Milwaukee Brewers vs Philadelphia Phillies

Date: Wednesday, September 23, 2026

Location: Citizens Bank Park in Philadelphia, PA

TV: NBC Sports Philadelphia

Odds/Point Spread: Milwaukee (-122) Philadelphia (+102)

Citizens Bank Park is the location where the Philadelphia Phillies (86-70) will attempt to defeat the Milwaukee Brewers (98-58) on Wednesday. The moneyline on this game has Milwaukee at -122 and Philadelphia is sitting at +102. The over/under is 8. The pitchers taking the mound will be Logan Henderson and Aaron Nola.

The Brewers have accrued 270 doubles as a squad and have knocked 149 baseballs out of the park. Milwaukee is slugging .403 and have been called out on strikes 1,323 times, while taking a walk on 648 occasions. As a team, the Milwaukee Brewers are notching 5.1 runs/g, which is 2nd in baseball. They have accrued 758 RBI's and 1,369 base knocks on the season, and their team batting average is .258. They are sitting with 802 runs and hold an on-base percentage of .341.

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They have earned a K/BB ratio of 2.98 and the pitching staff has earned a collective WHIP of 1.19. Brewers pitchers have given up 165 home runs and 600 runs in total (4th in MLB). Milwaukee has surrendered 1,155 base hits (7.5 per 9 innings) as well as 548 earned runs. The Brewers have a team ERA of 3.54 this year (2nd in baseball), and the staff has rung up 1,492 batters. Their pitching staff has walked 500 players from the other team and their FIP is 3.71 as a unit for the year.

Brewers relief pitchers have entered the contest with runners on base 127 times as well as having 155 appearances in high leverage situations. The relief pitchers have recorded 82 holds over the course of the season (18th in the league). The Brewers relievers have accumulated a save percentage of 71.8% and stepped onto the hill in 155 save situations. They have 51 saves this season and have blown 20 of 71 save chances. The relief pitchers have inherited 185 base runners on the campaign with 37.8% of those players earned a run for their team. The Brewers have dispatched 490 relievers to the mound so far this season.

The Brewers have turned 71.0% of balls in play into outs in their 12,543 innings on the diamond, which ranks them 8th in professional baseball. The Milwaukee Brewers have a tally of 4,181 putouts thus far, as well as 1,224 assists and 68 errors. Their fielding percentage is holding at .988 which has them sitting 7th in baseball, and have a total of 116 double plays.

Henderson (13-3 win-loss record in his career) holds a FIP of 2.33 and he has faced 448 hitters during his time in the majors. He has given up 77 base hits (5.9 hits per 9 innings) and has had 24 free passes. His earned run average is 2.36 (31 earned runs allowed) and he has a WHIP of 0.854. Henderson has pitched in 118 innings and has accounted for 140 K's in his pro baseball career.

The Philadelphia Phillies have accounted for an OBP of .312 as well as a batting average of .241 so far this year. They have struck out on 1,282 occasions (19th in MLB) and have totaled 1,260 base knocks. Philadelphia has knocked in 179 long balls for the year as well as 677 runs batted in. The Phillies have a team slugging percentage of .397 and they score 4.47 runs per game (14th in baseball). They have recorded 232 two-baggers, while getting a free base 506 times and scoring 697 runs.

The Philadelphia pitching staff have allowed 668 runs so far this year while having a team ERA of 4.01 (616 earned runs conceded). They have given up 184 long balls and they yield 4.34 runs per 9 innings (10th in baseball). The Phillies have a team WHIP of 1.286 in addition to having a FIP of 3.81 as a pitching staff on the year. Their strikeout to walk ratio is 9.80 (1,510 strikeouts against 468 free passes). They are sitting at 21st in baseball as a staff in total hits surrendered with 1,312.

Philadelphia relief pitchers have an inherited score percentage of 37.7% of 162 inherited runners. Their bullpen pitchers have come in 153 times in high leverage situations and also on 117 occasions with base runners. Sitting with 139 save situations, the Phillies have amassed 73 holds and 23 blown saves. They sit at 15th in the league holding a save percentage of 64.1%, and they have dispatched 510 bullpen pitchers to the mound for the season.

The Philadelphia Phillies have turned 101 double plays and hold a fielding percentage of .986 (14th in pro baseball). The Phillies have accrued 1,290 assists, 77 errors and have a tally of 4,153 putouts for the year. In their 12,459 innings played, the Phillies have accumulated a defensive efficiency of 67.9% (28th in pro baseball).

In his pro baseball career, Nola has conceded 1,691 base knocks and he has 2,045 punch outs in 1,883 frames. He has allowed a total of 814 ER's while holding a WHIP of 1.167 and a FIP of 3.8. He has a K/BB ratio of 4.03 and he has faced 7,753 opposing hitters in his pro baseball career. Nola (116-99 record in his career) has earned a 3.89 earned run average and has given up 8.1 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Milwaukee (-122)

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