Pittsburgh Pirates vs Cincinnati Reds Prediction, 4/1/2026 MLB Picks, Best Bets & Odds

Game: Pittsburgh Pirates vs Cincinnati Reds

Date: Wednesday, April 1, 2026

Location: Great American Ball Park in Cincinnati, OH

TV: Reds.TV

Odds/Point Spread: Pittsburgh (+150) Cincinnati (-182)

The Cincinnati Reds (3-1) will try to defeat the Pittsburgh Pirates (1-3) at Great American Ball Park on Wednesday. The moneyline on this contest has Pittsburgh at +150 and Cincinnati is at -182. The total comes in at 9. The pitchers who are expected to start are Paul Skenes and Andrew Abbott.

As a squad, the Pittsburgh Pirates are notching 3.3 runs per game, which is 23rd in MLB. They have tallied 13 runs while holding a team OBP of .307. The Pirates have tallied 5 two-baggers as a team and have hit 4 balls out of the stadium. They have 13 runs batted in as well as 33 hits this season, while their batting average is sitting at .223. Pittsburgh has a slugging % of .338 and have struck out 42 times, while being walked on 17 occasions.

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Their strikeout to walk ratio is 1.95 and their pitching staff has a collective WHIP of 1.42. Pirates pitchers have conceded 3 home runs and 20 total runs (21st in the league). Pittsburgh has surrendered 30 hits (7.5 per 9 innings) and 17 earned runs. The Pirates have an ERA of 4.25 so far this year (19th in the league), and their staff has rung up 41 hitters. Their pitching staff has walked 21 opposing players and their FIP sits at 3.94 as a unit for the year.

The Pirates have dispatched 17 relief pitchers to the hill over the course of the season. The relief pitchers have inherited 6 runners for the year with 16.7% of them ended up crossing the plate. The relief pitchers have no holds on the season (30th in MLB). Pirates relief pitchers have entered the contest with runners on 6 times and also have had 9 appearances in high leverage situations.

The Pirates have turned 69.2% of baseballs in play into outs out of 324 innings on the field, which has them sitting at 22nd in baseball. The Pittsburgh Pirates are sitting with 108 putouts over the course of the season, as well as 24 assists and 2 errors. Their fielding percentage is at .985 which has them sitting 20th in professional baseball, and have accumulated 1 double play.

Skenes (21-14 record in his career) holds a FIP of 2.08 while he has gone up against 1,256 opposing hitters during his time in the majors. He has surrendered 234 base hits (6.6 hits per 9 innings) and has had 76 walks. His earned run average is 2.11 (75 ER's allowed) and he has a career WHIP of 0.968. Skenes has thrown 320 innings and is sitting with 387 strikeouts in his pro baseball career.

Cincinnati has knocked in 3 HRs this season to go along with 11 runs batted in. They have put up 4 doubles, while taking a walk 19 times as well as putting up 11 runs. The Cincinnati Reds have a team on-base percentage of .295 and a batting average of .194 this year. The Reds hold a slugging percentage of .310 and they are earning 2.75 runs per game (26th in MLB). They have struck out on 40 occasions (12th in baseball) and have 25 base hits.

The Cincinnati pitching staff have allowed 10 runs on the campaign while holding an ERA of 2.37 (10 earned runs allowed). They have given up 3 homers and they relinquish 2.37 runs per 9 innings (3rd in MLB). The Reds have a team WHIP of 1.316 and are the owners of a FIP of 3.79 as a unit for the season. Their strikeout to walk ratio is 9.50 (40 strikeouts vs 19 free passes). They come in at 15th in the league as a pitching staff in total hits allowed with 31.

They rank 15th in MLB with a save percentage of 66.7%, and they have sent 18 relief pitchers onto the field for the season. Their relievers have stepped onto the mound 7 times in high leverage situations and also on 7 occasions with base runners.

Out of their 342 innings played, the Reds have a defensive efficiency of 71.0% (16th in MLB). The Cincinnati Reds have turned 5 double plays and have accounted for a fielding rate of 1.000 (5th in pro baseball). The Reds have recorded 37 assists, no errors and have earned 114 putouts for the year.

So far in his career, Abbott has allowed 382 hits while accumulating 387 K's in 419 innings pitched. Abbott (28-23 win-loss record in his career) holds a 3.37 earned run average and has allowed 8.2 hits per nine innings. He has allowed 157 ER's while earning a WHIP of 1.245 and having a FIP of 3.3. He has a strikeout to walk ratio of 2.76 and he has gone up against 1,753 hitters so far in his pro baseball career.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Pittsburgh (+150)

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