Alabama Crimson Tide vs Missouri Tigers Prediction, 10/11/2025 College Football Picks, Best Bets & Odds

Game: Alabama Crimson Tide vs Missouri Tigers

Date: Saturday, October 11, 2025

Location: Memorial Stadium in Columbia, MO

TV: ABC

Odds/Point Spread: Tigers (+3.5)

Total/Over-Under: 53

Memorial Stadium is the location where the Missouri Tigers (5-0) will compete against the Alabama Crimson Tide (4-1) on Saturday, October 11, 2025. Alabama opens this matchup as 3.5-point favorites from oddsmakers. The betting total is set at 53.

The Alabama Crimson Tide come into this game with a record of 4-1 for this season. In their last contest, the Crimson Tide took the field against the Vanderbilt Commodores and earned the victory with a final of 30-14. On the day, they ran 69 plays for 486 yds. The Alabama Crimson Tide ended up running the ball 38 times and compiled 146 yds, which came out to an average of 3.8 yds per carry. Against the run, the Crimson Tide gave up 135 yards on 19 tries, which averages out to 7.1 yds per run allowed. Alabama allowed 21 pass completions on 36 attempts for a total of 198 yds, and a completion percentage of 58.3%.

When talking about putting the ball in the endzone, the Alabama Crimson Tide are sitting at 36.4 PPG. As a unit they're maintaining an average of 126.8 yards on the ground ranking them 105th in the country. The Crimson Tide have earned 2,261 total yards over the course of this season. When it comes to scoring, Alabama has totaled 17 touchdowns via the pass and 6 rushing touchdowns. Alabama has compiled 120 first downs, and they have been hurt by 27 infractions for 228 yds. They have given the ball to the opposition 1 time.

When talking about yards via the pass, the Crimson Tide are giving up 652 yds which puts them in 5th in the country. They have given up 130.4 yards per game through the air as well as giving up a completion percentage of 61.0%. For the year, they have given up 285.8 yards/contest putting them at 20th in college football. They have yielded 3 touchdowns via the pass as well as 7 touchdowns via the ground game. They are allowing teams to run for an average of 4.7 yards per run and 155.4 yards on the ground per contest for the year. During this campaign, they have given up 777 running yards through 5 contests. The Crimson Tide are ranked 21st in the country in terms of their opponents scoring, allowing 16.0 points per game.

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The Tigers head into this matchup 5-0 for this year. The last time they took the field, the Tigers went home victorious with a score of 42-6 against the UMass Minutemen. The Tigers ended up finishing with 521 yds on 84 plays (6.2 yds per play). Missouri rushed the football for 5.2 yards per attempt, finishing the game with 268 yds on 52 attempts. Missouri gave up 16 running attempts for 19 yards (1.2 yards per carry). The Tigers passing defense allowed a completion rate of 35.9%, surrendering 105 yds on 14 out of 39 passing.

In terms of their scoring prowess, the Tigers are sitting 7th in college football averaging 45.2 points per game. The Missouri Tigers average 547.6 yards/game, which has them sitting 4th in college football. The Missouri offense has 234 yards of penalties on 24 violations, which ranks 112th in Division 1 in terms of giving up free yards. They have given away 3 interceptions while conceding 1 fumble and they have recorded 145 first downs. Over the course of the season thus far, the Tigers have thrown for a total of 1,278 yards via the pass as well as an average of 255.6 passing yards per game, which has them ranked 51st in D-1. They are averaging 292.0 yards via the ground game and have rushed for 1,460 yards in total.

The Tigers are surrendering 14.6 points per game, which has them sitting 16th in D-1. Missouri has allowed a total of 312 yards rushing (62.4 yards/game) as well as 2 touchdowns on the ground this year. They have conceded 6 touchdowns through the air and 141.4 yards/outing, which has them in 10th in D-1. The Tigers defense has been on the field for 252 plays, which is good for 1st in Division 1. Their defense has earned 1 fumble and 3 interceptions over the course of the season. In total, they have relinquished 73 pts.

Who will win tonight's Crimson Tide/Tigers college football game against the spread?

Tony's Pick: Take the Tigers +3.5

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