Arizona State Sun Devils vs Colorado Buffaloes Prediction, 11/22/2025 College Football Picks, Best Bets & Odds

Game: Arizona State Sun Devils vs Colorado Buffaloes

Date: Saturday, November 22, 2025

Location: Folsom Field in Boulder, CO

TV: ESPN2

Odds/Point Spread: Buffaloes (+7.0)

Total/Over-Under: 49

Folsom Field is the location where the Colorado Buffaloes (3-7) will attempt to defeat the Arizona State Sun Devils (7-3) on Saturday, November 22, 2025. Arizona State is 7.0-point favorites from oddsmakers. The total is 49.

The Arizona State Sun Devils step onto the field holding a record of 7-3 this season. The last time they took the field, the Sun Devils played the West Virginia Mountaineers and went home with a win by a final score of 25-23. In the running game, the Sun Devils gave up 68 yards on 39 attempts, which is an average of 1.7 yds per run surrendered. Arizona State allowed 19 completions on 31 tries for 353 yards, and a completion rate of 61.3%. In the game, they had 67 plays which gave them a total of 330 yds. The Arizona State Sun Devils ended up rushing 39 different times and compiled 123 yards, which had them averaging 3.2 yards per carry.

Concerning scoring, the Arizona State Sun Devils have an average of 24.7 points per game. As a team they're maintaining an average of 181.2 yards in the run game giving them a rank of 39th in Division 1. The Sun Devils have earned 4,006 total yards over the course of this season. In terms of scoring touchdowns, Arizona State has compiled 15 touchdowns via the pass and 12 rushing touchdowns. Arizona State has a total of 217 1st downs as an offense, and they have been flagged for 80 infractions for 628 yards. They have given the ball to the opposition 9 times.

The Sun Devils rank 66th in D-1 when it comes to team defense, giving up 23.6 points per game. They are allowing teams to run for an average of 3.5 yards per rushing attempt and 117.7 rushing yards per contest for the year. For the year, they have given up 1,177 rushing yards through 10 outings. In terms of yards through the air, the Sun Devils are allowing 2,257 yds which puts them in 78th in college football. They have given up 225.7 yards per outing via the pass in addition to conceding a completion percentage of 61.7%. Over the course of this year, they are giving up 343.4 yards/contest which puts them 46th in the nation. They have conceded 14 touchdowns through the air and 16 touchdowns via the ground game.

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The Buffaloes head into this game 3-7 for this season. The last time they took the field, the Buffaloes took a loss by a score of 29-22 against the West Virginia Mountaineers. The Buffaloes finished the game with 350 yards on 73 plays (4.8 yards per play). Colorado rushed the ball for 1.3 yards per attempt, finishing the contest with 51 yards on 38 attempts. Colorado relinquished 53 running attempts for 167 yds (3.2 yds per carry). The Buffaloes pass defense conceded a completion percentage of 60.7%, surrendering 202 yards on 17 out of 28 through the air.

When it comes to how much they score, the Buffaloes are sitting 108th in the nation holding an average of 22.0 points per outing. The Colorado Buffaloes have an average of 331.8 yards/contest, which has them sitting 112th in the country. The Colorado offense has compiled 521 penalty yds on 60 violations, which is good for 82nd in the nation in terms of helping out the opposition. They have thrown 10 interceptions while conceding 5 fumbles and they have tallied 178 1st downs. During the season to this point, the Buffaloes have thrown for 2,097 yards via the pass together with an average of 209.7 passing yards per outing, putting them at 90th in the country. They average 122.1 yards per game via the rush and have run for 1,221 yards for the year.

Colorado has given up a total of 2,109 rushing yards (210.9 yards per outing) as well as 19 touchdowns via the rush so far this season. They have allowed 16 touchdowns via the pass in addition to 209.8 yards/contest, which has them sitting 55th in D-1. In total, they have surrendered 300 pts. Their defense has tallied 6 fumbles and 5 interceptions over the course of the season. The Buffaloes defense has taken part in 701 plays, which ranks them 100th in college football. The Buffaloes are conceding 30.0 points per contest, which has them ranked 108th in Division 1.

Who will win tonight's Sun Devils/Buffaloes college football game against the spread?

Josh's Pick: Take the Sun Devils -7.0

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