Arizona State Sun Devils vs Iowa State Cyclones Prediction, 11/1/2025 College Football Picks, Best Bets & Odds

Game: Arizona State Sun Devils vs Iowa State Cyclones

Date: Saturday, November 1, 2025

Location: Jack Trice Stadium in Ames, IA

TV: TNT

Odds/Point Spread: Cyclones (-5.5)

Total/Over-Under: 50.5

The Arizona State Sun Devils (5-2) are headed to Jack Trice Stadium on Saturday, November 1, 2025 where they will take on the Iowa State Cyclones (5-3). Iowa State opens as 5.5-point favorites from Vegas oddsmakers. The total is set at 50.5.

The Arizona State Sun Devils head into this game 5-2 this season. The last time they stepped onto the field, the Sun Devils played the Houston Cougars and walked away from this one with a loss by a score of 24-16. The Arizona State Sun Devils ran the ball a total of 21 different times and had 98 yds, which earned them an average of 4.7 yards per tote. In all, they tallied 67 plays which gave them 426 yds. Arizona State surrendered 17 completions on 22 tries for a total of 201 yds, and a completion rate of 77.3%. When it came to stopping the run, the Sun Devils conceded 183 yards on 48 attempts, which calculates to 3.8 yds per run allowed.

Regarding scoring, the Arizona State Sun Devils are averaging 24.8 points per game. As a unit they average 174.9 yards on the ground which has them sitting 48th in D-1. The Sun Devils have racked up 3,209 total yards for this campaign. When it comes to distribution of touchdowns, Arizona State has compiled 11 touchdowns via the pass and 10 rushing touchdowns. Arizona State has accrued 179 1st downs offensively, and they have committed 64 infractions for 478 yds. They have surrendered the football 5 times.

When talking about yards through the air, the Sun Devils have given up 1,718 yds which has them ranked 76th in the country. They are conceding 214.8 yards per game via the pass and allowed a completion percentage of 63.8%. For the season, they have allowed 334.6 yards/contest which ranks them 38th in college football. They have surrendered 11 touchdowns through the air as well as 14 touchdowns on the ground. They are allowing 3.6 yards per rush and 119.9 rushing yards per game this season. During this campaign, they have given up 959 rushing yards through 8 games. The Sun Devils are ranked 70th in the country regarding the opposition scoring, conceding 24.3 points per game.

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The Cyclones come into this game with a record of 5-3 for this year. When they last stepped on the field, the Cyclones went home defeated by a final of 41-27 when they played the BYU Cougars. Iowa State ran the ball for 5.4 yards per tote, totaling 184 yards on 34 attempts. The Cyclones finished the game with a total of 495 yds and they ran 70 plays (7.1 yards per play). The Cyclones pass defense conceded a completion percentage of 61.1%, relinquishing 307 yds on 22 for 36 passing. Iowa State gave up 28 running attempts for 103 yards (3.7 yds per carry).

The Iowa State Cyclones average 417.1 yards/contest, which ranks them 45th in D-1. The Iowa State offense has totaled 271 yards of penalties on 33 violations, which is good for 123rd in D-1 in terms of hurting your team. They average 166.4 yards per game via the rush and have run for 1,331 yards for this year. They have given away 6 interceptions while losing 4 fumbles and they have been able to earn 175 1st downs. Concerning this team's ability to score points, the Cyclones are sitting 67th in Division 1 with 29.0 points per outing. During this campaign so far, the Cyclones have thrown for 2,006 passing yards as well as holding an average of 250.8 passing yards per outing, putting them at 47th in the nation.

Iowa State has allowed a total of 1,094 yards via the ground game (136.8 yards per game) and 9 touchdowns via the rush so far this season. They have allowed 11 touchdowns via the pass as well as 216.6 yards per outing, which has them in 63rd in Division 1. Overall, they have allowed 174 total points. Their defense has earned 3 fumbles and 6 interceptions this year. The Cyclones defense has taken the field for 503 plays, which is 63rd in college football. The Cyclones are allowing 21.8 points per game, which has them sitting 48th in the nation.

Who will win tonight's Sun Devils/Cyclones college football game against the spread?

Tony's Pick: Take the Sun Devils +5.5

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