Baylor Bears vs Oklahoma State Cowboys Prediction, 9/27/2025 College Football Picks, Best Bets & Odds

Game: Baylor Bears vs Oklahoma State Cowboys

Date: Saturday, September 27, 2025

Location: Boone Pickens Stadium in Stillwater, OK

TV: ESPN2

Odds/Point Spread: Cowboys (+20.5)

Total/Over-Under: 59.5

The Oklahoma State Cowboys (1-2) will try to defeat the Baylor Bears (2-2) at Boone Pickens Stadium on Saturday, September 27, 2025. Baylor opens this contest as 20.5-point favorites from Vegas oddsmakers. The betting total comes in at 59.5.

The Baylor Bears come into this matchup with a record of 2-2 for this season. In their last matchup, the Bears took the field against the Arizona State Sun Devils and took a loss by a final of 27-24. The Baylor Bears ran the football 23 different times and accumulated 107 yards, which came out to an average of 4.7 yards per carry. In all, they ran 62 plays which gave them a total of 357 yds. Baylor allowed 22 pass completions on 32 tries for a total of 221 yards, and a completion rate of 68.8%. Against the rush, the Bears gave up 179 yards on 48 attempts, which is an average of 3.7 yds per rush allowed.

Regarding scoring, the Baylor Bears have an average of 34.5 points per outing. As a team they're maintaining an average of 138.8 yards rushing which ranks them 93rd in the country. The Bears have earned 1,909 total yards over the course of this year. When it comes to scoring, Baylor has earned 13 touchdowns through the air and 5 rushing touchdowns. Baylor has tallied 102 1st downs as an offense, and they have been called for 23 infractions for 250 yds. They have turned the football over 7 times.

The Bears are ranked 107th in Division 1 when it comes to team defense, allowing 29.3 points per contest. They are giving up an average of 4.2 yards per rush on the ground and 186.0 rushing yards per game this year. For the season, they have given up 744 running yards through 4 games. In terms of yards through the air, the Bears are allowing 724 yards which puts them in 60th in D-1. They have allowed 181.0 yards per contest through the air as well as conceding a completion percentage of 64.6%. Overall, they are granting 367.0 yards per game putting them at 80th in the nation. They have yielded 5 touchdowns via the pass and 8 touchdowns on the ground.

Get all of our Free College Football Picks

The Cowboys come into this game with a record of 1-2 for this season. In their last game, the Cowboys went home defeated by a final of 19-12 against the Tulsa Golden Hurricane. The Cowboys finished with a total of 403 yds and they ran 75 plays (5.4 yds per play). Oklahoma State ran the ball for 5.6 yds per carry, finishing the game with 185 yards on 33 attempts. Oklahoma State relinquished 43 attempts on the ground for 205 yards (4.8 yards per rush). The Cowboys pass defense gave up a completion rate of 63.9%, relinquishing 219 yds on 23 for 36 through the air.

The Oklahoma State Cowboys maintain an average of 324.3 yards/game, which has them sitting 114th in D-1. The Oklahoma State offense has compiled 130 penalty yards on 16 infractions, which is 113th in D-1 in terms of hurting your team. They have an average of 152.0 yards per game via the rush and have rushed for 456 yards for this year. They have given away 2 picks while losing 0 fumbles and they have been able to earn 53 first downs. In terms of how much they score, the Cowboys rank 134th in D-1 holding an average of 14.0 PPG. During this campaign to this point, the Cowboys have compiled 517 yards via the pass as well as holding an average of 172.3 passing yards per game, ranking them 115th in Division 1.

The Cowboys are conceding 31.7 points per game, ranking them 115th in the country. Oklahoma State has surrendered a total of 633 rushing yards (211.0 yards per game) and 5 touchdowns rushing this season. They have surrendered 5 touchdowns through the air as well as 215.7 yards per game, ranking them 80th in the country. The Cowboys defense has been on the field for 196 plays, which ranks 27th in college football. Their defense has totaled 1 fumble recovered and 1 pick for the year. Over the course of the season, they have allowed 95 total points.

Who will win tonight's Bears/Cowboys college football game against the spread?

Tony's Pick: Take the Bears -20.5

Get $60 worth of FREE premium member picks. No Obligation. No Salesman. No Credit Card. Fast Sign up with Instant Access Click Here