Boston College Eagles vs Stanford Cardinal Prediction, 9/13/2025 College Football Picks, Best Bets & Odds
Game: Boston College Eagles vs Stanford Cardinal
Date: Saturday, September 13, 2025
Location: Stanford Stadium in Stanford, CA
TV: ESPN/ESPN+
Odds/Point Spread: Cardinal (+10.5)
Total/Over-Under: 45
The Boston College Eagles (1-1) are headed to Stanford Stadium on Saturday, September 13, 2025 where they will play the Stanford Cardinal (0-1). Boston College is 10.5-point favorites. The betting total is set at 45.
The Boston College Eagles come into this game with a record of 1-1 for this year. The last time they stepped onto the field, the Eagles took on the Michigan State Spartans and ended up losing by a score of 42-40. On the day, they ran 70 plays which converted into 457 yards. The Boston College Eagles ran the ball 25 different times and accumulated 67 yards, earning them an average of 2.7 yds per attempt. Against the rush, the Eagles gave up 149 yds on 35 attempts, which averages out to 4.3 yds per run surrendered. Boston College conceded 19 completions on 29 tries for 231 yds, and a completion rate of 65.5%.

The Eagles have racked up 1,012 total yards for this campaign. When it comes to distribution of touchdowns, Boston College has amassed 9 passing touchdowns and 4 rushing touchdowns. They have surrendered the ball 1 time. Boston College has recorded 51 first downs as a team, and they have committed 9 penalties for 74 yds. As a team they hold an average of 82.0 yards on the ground ranking them 124th in the country. When it comes to scoring points, the Boston College Eagles are sitting at 53.0 PPG.
The Eagles rank 96th in D-1 regarding team defense, allowing 26.0 points per game. The opposition is running for 2.7 yards per tote and 82.5 rushing yards per contest on the season. For the season, they have conceded 165 yards via the running game in 2 games. Concerning yards via the pass, the Eagles have given up 383 yards which has them ranked 62nd in D-1. They are allowing 191.5 yards per contest via the pass in addition to allowing a completion percentage of 57.4%. During this campaign, they are allowing 274.0 yards per contest ranking them 42nd in the nation. They have allowed 4 touchdowns through the air in addition to 2 touchdowns via the ground game.
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The Cardinal head into this matchup 0-1 for this season. The last time they took the gridiron, the Cardinal took a loss by a score of 27-3 when they played the BYU Cougars. Stanford ran for 0.8 yds per carry, finishing the game with 19 yds on 24 attempts. The Cardinal finished the contest with a total of 161 yards and they ran 56 plays (2.9 yards per play). The Cardinal pass defense allowed a completion percentage of 63.0%, surrendering 175 yds on 17 for 27 through the air. Stanford gave up 41 attempts on the ground for 157 yards (3.8 yards per rush).
The Stanford Cardinal have an average of 223.5 yards per game, which has them ranked 132nd in the nation. The Stanford offense has racked up 115 yards of penalties on 13 violations, which ranks 56th in the nation in terms of hurting your team. They maintain an average of 98.0 yards per game via the ground game and have toted the ball for 196 yards in total. They have obtained 33 1st downs. In relation to putting points on the board, the Cardinal are ranking 129th in D-1 by tallying 11.5 PPG. Over the course of the season to this point, the Cardinal have thrown for a total of 251 yards through the air as well as holding an average of 125.5 passing yards per outing, which has them ranked 124th in the nation.
The Cardinal are conceding 25.0 points per game, which has them sitting 93rd in the nation. Stanford has conceded a total of 253 yards rushing (126.5 yards per game) in addition to 2 touchdowns via the rush for the campaign. They have allowed the opposition 2 touchdowns via the pass as well as 192.5 yards per game, which has them in 65th in the nation. The Cardinal defense has taken the field for 132 plays, which ranks 77th in college football. Their defense has tallied 1 fumble recovery and 0 interceptions on the campaign.
Who will win tonight's Eagles/Cardinal college football game against the spread?
Guy's Pick: Take the Cardinal +10.5
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Additional Resources:
Stanford Cardinal - Twitter
Boston College Eagles - Twitter