California Golden Bears vs Stanford Cardinal Prediction, 11/22/2025 College Football Picks, Best Bets & Odds

Game: California Golden Bears vs Stanford Cardinal

Date: Saturday, November 22, 2025

Location: Stanford Stadium in Stanford, CA

TV: ACC Network

Odds/Point Spread: Cardinal (+3.0)

Total/Over-Under: 47.5

The Stanford Cardinal (3-7) will go up against the California Golden Bears (6-4) at Stanford Stadium on Saturday, November 22, 2025. California is 3.0-point favorites. The betting total comes in at 47.5.

The California Golden Bears come into this matchup with a record of 6-4 this year. In their last contest, the Golden Bears took the field against the Louisville Cardinals and took home the win by a score of 29-26. On the ground, the Golden Bears conceded 148 yards on 30 attempts, which is 4.9 yds per run allowed. California surrendered 20 completions on 39 tries for 203 yards, and a completion percentage of 51.3%. Once the final whistle blew, they tallied 74 plays for 427 yards. The California Golden Bears ran the ball a total of 25 times and totaled 77 yds, which earned them an average of 3.1 yards per carry.

When talking about getting in the endzone, the California Golden Bears are averaging 25.0 PPG. As a unit they maintain an average of 78.4 yards on the ground ranking them 134th in the nation. The Golden Bears have attained 3,419 total yards this season. In terms of getting the ball in the endzone, California has totaled 15 touchdowns through the air and 16 touchdowns via the ground. California has earned 190 first downs as a team, and they have committed 73 infractions for 560 yds. They have given the ball to the opposition 12 times.

When talking about yards via the pass, the Golden Bears are giving up 1,992 yards which has them ranked 41st in college football. They are conceding 199.2 yards per outing through the air in addition to allowing a completion percentage of 60.6%. Overall, they have relinquished 354.9 yards/game putting them 55th in the nation. They have conceded 7 touchdowns via the pass and 20 touchdowns via the ground game. They are allowing teams to run for an average of 4.6 yards per rushing attempt and 155.7 rushing yards per game on the year. Over the course of this year, they have allowed 1,557 yards via the ground game in 10 games. The Golden Bears rank 75th in D-1 regarding their opponents scoring, conceding 25.2 points per contest.

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The Cardinal come into this game with a record of 3-7 this year. When they last stepped on the gridiron, the Cardinal walked away with a loss by a score of 20-15 against the North Carolina Tar Heels. The Cardinal finished the contest with a total of 320 yards and they ran 74 plays (4.3 yds per play). Stanford ran for 1.0 yards per carry, finishing with 36 yards on 35 attempts. Stanford relinquished 27 attempts on the ground for 50 yds (1.9 yards per rush). The Cardinal pass defense allowed a completion rate of 72.0%, relinquishing 203 yds on 18 out of 25 through the air.

The Stanford Cardinal maintain an average of 308.4 yards/game, ranking them 120th in the nation. The Stanford offense has accrued 586 yds of penalties on 63 infractions, which ranks them 64th in D-1 in terms of giving up free yards. They average 76.9 rushing yards per game and have run for 769 yards for the year. They have given away 11 picks while losing 5 fumbles and they have been able to record 176 first downs. Regarding this team's ability to score points, the Cardinal are ranked 129th in D-1 holding an average of 17.5 points per contest. For the year so far, the Cardinal have a total of 2,315 yards via the pass along with an average of 231.5 passing yards per game, which has them sitting 67th in D-1.

The Cardinal are allowing 29.1 PPG, which has them ranked 98th in D-1. Stanford has conceded a total of 1,232 yards via the ground game (123.2 yards per contest) in addition to 12 touchdowns via the rush for the season. They have given up 19 touchdowns through the air and 284.5 yards per contest, which has them sitting 134th in college football. The Cardinal defense has taken part in 676 plays, which ranks 81st in Division 1. Their defense has earned 7 fumbles recovered and 3 interceptions this season. This year, they have conceded 291 points.

Who will win tonight's Golden Bears/Cardinal college football game against the spread?

Guy's Pick: Take the Golden Bears -3.0

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