Charlotte 49ers vs East Carolina Pirates Prediction, 11/8/2025 College Football Picks, Best Bets & Odds

Game: Charlotte 49ers vs East Carolina Pirates

Date: Saturday, November 8, 2025

Location: Dowdy-Ficklen Stadium in Greenville, NC

TV: ESPN+

Odds/Point Spread: Pirates (-28.5)

Total/Over-Under: 57

Dowdy-Ficklen Stadium is where the East Carolina Pirates (5-3) will compete against the Charlotte 49ers (1-7) on Saturday, November 8, 2025. Charlotte opens this contest as 28.5-point underdogs. The betting total comes in at 57.

The Charlotte 49ers come into this game with a record of 1-7 this season. The last time they stepped onto the field, the 49ers took on the North Texas Mean Green and took a loss by a final of 54-20. For the game, they ran 63 plays which totaled 399 yards. The Charlotte 49ers ran the ball 27 different times and accounted for 104 yds, which earned them an average of 3.9 yds per carry. When it came to the battle of the line of scrimmage, the 49ers gave up 146 yds on 29 attempts, which is 5.0 yards per rush surrendered. Charlotte gave up 37 completions on 49 attempts for 608 yds, and a completion percentage of 75.5%.

The 49ers have attained 2,599 total yards over the course of this season. In terms of scoring touchdowns, Charlotte has earned 11 passing touchdowns and 5 touchdowns via the ground. They have given the ball to the opposition 16 times. Charlotte has compiled 147 1st downs as a unit, and they have committed 50 penalties for 424 yds. As a team they're maintaining an average of 106.8 yards via the ground game which ranks them 123rd in D-1. In terms of getting in the endzone, the Charlotte 49ers are averaging 17.5 points per game.

When talking about passing yards, the 49ers have given up 2,161 yards which ranks them 117th in D-1. They are giving up 270.1 yards per outing via the pass and allowed a completion percentage of 68.5%. In total, they are giving up 477.9 yards per contest which has them sitting 135th in the nation. They have surrendered 20 touchdowns via the pass in addition to 17 touchdowns on the ground. They are allowing teams to run for an average of 5.1 yards per rush on the ground and 207.8 rushing yards per game for the campaign. Overall, they have given up 1,662 rushing yards through 8 contests. The 49ers sit in 132nd in the nation regarding the opposition scoring, allowing 37.3 PPG.

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The Pirates head into this game 5-3 for this season. For their last game, the Pirates went home victorious with a score of 45-14 against the Temple Owls. The Pirates finished the game with 614 yds on 75 plays (8.2 yds per play). East Carolina ran for 7.0 yds per carry, totaling 358 yards on 51 carries. East Carolina relinquished 30 running attempts for 82 yds (2.7 yards per rush). The Pirates pass defense conceded a completion percentage of 60.0%, relinquishing 151 yards on 15 for 25 passing.

The East Carolina Pirates maintain an average of 475.3 yards per game, which is good for 13th in college football. The East Carolina offense has 465 yards of penalties on 57 infractions, which has them sitting 47th in D-1 in terms of helping out the other team. They hold an average of 186.4 yards per game on the ground and have toted the ball for 1,491 yards for this year. They have thrown 5 picks while allowing opponents to recover 2 fumbles and they have recorded 196 1st downs. Concerning their ability to score points, the Pirates are ranked 45th in D-1 with an average of 32.1 PPG. Over the course of the season so far, the Pirates have compiled 2,311 passing yards as well as an average of 288.9 throwing yards per game, ranking them 17th in college football.

The Pirates are allowing 16.8 points per contest, ranking them 15th in Division 1. East Carolina has given up a total of 914 rushing yards (114.3 yards per outing) in addition to 8 touchdowns on the ground this season. They have given up 6 touchdowns through the air as well as 212.0 yards per game, which puts them in 59th in Division 1. The Pirates defense has been on the field for 523 plays, which ranks 29th in college football. They have totaled 7 fumbles and 4 picks so far this year. Overall, they have conceded 134 total points.

Who will win tonight's 49ers/Pirates college football game against the spread?

Guy's Pick: Take the Pirates -28.5

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