Coastal Carolina Chanticleers vs South Alabama Jaguars Prediction, 9/20/2025 College Football Picks, Best Bets & Odds
Game: Coastal Carolina Chanticleers vs South Alabama Jaguars
Date: Saturday, September 20, 2025
Location: Hancock Whitney Stadium in Mobile, AL
TV: ESPN+
Odds/Point Spread: Jaguars (-14.5)
Total/Over-Under: 50.5
Hancock Whitney Stadium is the location where the South Alabama Jaguars (1-2) will attempt to defeat the Coastal Carolina Chanticleers (1-2) on Saturday, September 20, 2025. South Alabama opens as 14.5-point favorites from Vegas oddsmakers. The betting total is set at 50.5.
The Coastal Carolina Chanticleers head into this matchup 1-2 for this season. In their last contest, the Chanticleers faced the East Carolina Pirates and walked away from this one with a loss by a score of 38-0. The Coastal Carolina Chanticleers ended up running the ball 26 times and amassed 67 yards, which came out to an average of 2.6 yds per carry. In all, they ran 65 plays which gave them a total of 239 yds. Coastal Carolina allowed 28 pass completions on 37 tries for a total of 293 yards, and a completion rate of 75.7%. On the ground, the Chanticleers conceded 204 yds on 49 attempts, which is an average of 4.2 yards per run allowed.

Concerning putting the ball in the endzone, the Coastal Carolina Chanticleers have an average of 6.7 points per game. As a team they average 134.3 yards on the ground which is 97th in D-1. The Chanticleers have tallied 877 total yards this season. When it comes to getting in the endzone, Coastal Carolina has earned 0 touchdowns through the air and 2 touchdowns via the ground. Coastal Carolina has compiled 58 1st downs as a unit, and they have been hurt by 22 penalties for 195 yards. They have surrendered the ball 11 different times.
Regarding yards via the pass, the Chanticleers have conceded 638 yds which puts them in 78th in the country. They have conceded 212.7 yards per contest via the pass as well as conceding a completion percentage of 63.1%. Overall, they are giving up 368.0 yards per game which has them ranked 89th in the nation. They have yielded 4 touchdowns via the pass as well as 6 touchdowns via the ground game. They are allowing 3.9 yards per attempt on the ground and 155.3 rushing yards per game on the season. Over the course of this year, they have allowed 466 rushing yards through 3 outings. The Chanticleers are sitting in 103rd in college football regarding team defense, giving up 28.7 points per game.
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The Jaguars come into this matchup with a record of 1-2 this year. When they last stepped on the field, the Jaguars took a loss by a final score of 31-15 when they played the Auburn Tigers. South Alabama ended up running for 3.3 yards per carry, finishing with 140 yds on 42 carries. The Jaguars finished the game with 310 yds while running 68 plays (4.6 yds per play). The Jaguars passing defense gave up a completion percentage of 54.2%, surrendering 142 yards on 13 for 24 through the air. South Alabama conceded 39 run attempts for 195 yards (5.0 yds per rush).
The South Alabama Jaguars average 366.0 yards/game, which has them sitting 86th in the country. The South Alabama offense has accrued 95 yds of penalties on 15 infractions, which is 84th in the country in terms of helping out the opposition. They average 174.3 yards per game via the rush and have rushed for 523 yards overall. They have given away 1 interception while surrendering 4 fumble and they have been able to tally 62 1st downs. In relation to their scoring prowess, the Jaguars are ranking 77th in D-1 by scoring 28.0 PPG. For the year thus far, the Jaguars have compiled 575 passing yards in addition to an average of 191.7 throwing yards per contest, giving them a rank of 95th in the country.
The Jaguars are surrendering 28.3 points per game, which puts them 102nd in D-1. South Alabama has surrendered a total of 603 yards on the ground (201.0 yards per outing) and 9 touchdowns rushing for the year. They have given up 2 touchdowns via the pass as well as 155.3 yards/contest, which puts them in 29th in the nation. The Jaguars defense has participated in 200 plays, which is 83rd in college football. They have tallied 4 fumbles and 1 pick so far this year. Over the course of the season, they have allowed 85 total points.
Who will win tonight's Chanticleers/Jaguars college football game against the spread?
Tony's Pick: Take the Chanticleers +14.5
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Additional Resources:
South Alabama Jaguars - Twitter
Coastal Carolina Chanticleers - Twitter