Colorado Buffaloes vs West Virginia Mountaineers Prediction, 11/8/2025 College Football Picks, Best Bets & Odds

Game: Colorado Buffaloes vs West Virginia Mountaineers

Date: Saturday, November 8, 2025

Location: Milan Puskar Stadium in Morgantown, WV

TV: TNT

Odds/Point Spread: Mountaineers (-6.5)

Total/Over-Under: 56.5

The West Virginia Mountaineers (3-6) will go up against the Colorado Buffaloes (3-5) at Milan Puskar Stadium on Saturday, November 8, 2025. Colorado opens this contest as 6.5-point dogs from Vegas oddsmakers. The over/under is 56.5.

The Colorado Buffaloes head into this game 3-5 for this season. The last time they stepped onto the field, the Buffaloes faced the Arizona Wildcats and took a loss by a score of 52-17. When it came to the battle of the line of scrimmage, the Buffaloes conceded 204 yds on 38 attempts, which is an average of 5.4 yards per run allowed. Colorado relinquished 11 completions on 25 tries for a total of 213 yards, and a completion rate of 44.0%. In all, they tallied 77 plays which gave them a total of 299 yards. The Colorado Buffaloes rushed the ball a total of 42 times and had 129 yards, which earned them an average of 3.1 yards per carry.

The Buffaloes have attained 2,968 yards in total this season. When it comes to getting in the endzone, Colorado has totaled 14 passing touchdowns and 12 touchdowns on the ground. They have turned the football over 14 times. Colorado has recorded 159 first downs as an offense, and they have been hurt by 54 penalties for 461 yards. As a team they're holding an average of 130.0 yards in the run game ranking them 101st in the nation. Regarding putting the ball in the endzone, the Colorado Buffaloes have an average of 22.0 points per outing.

When talking about passing yards, the Buffaloes have given up 1,896 yards which has them ranked 75th in the country. They have surrendered 210.7 yards per contest through the air as well as allowing a completion percentage of 55.7%. Overall, they are granting 426.4 yards per outing which puts them 120th in the nation. They have surrendered 15 touchdowns via the pass in addition to 17 touchdowns via the ground game. They are giving up 5.3 yards per rush and 215.8 rushing yards per game so far this year. Over the course of this season, they have given up 1,942 yards on the ground through 9 games. The Buffaloes sit in 107th in college football in terms of their opponents scoring, allowing 30.1 points per game.

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The Mountaineers head into this matchup 3-6 for this season. In their last game, the Mountaineers walked away with a victory by a final of 45-35 when they played the Houston Cougars. West Virginia ran for 4.6 yds per attempt, finishing the game with 246 yds on 53 carries. The Mountaineers finished the game with a total of 403 yds while they ran 75 plays (5.4 yds per play). The Mountaineers secondary allowed a completion rate of 72.2%, surrendering 318 yds on 26 for 36 through the air. West Virginia allowed 31 rushing attempts for 82 yds (2.6 yds per carry).

The West Virginia Mountaineers have an average of 358.2 yards/game, which ranks them 93rd in Division 1. The West Virginia offense has racked up 496 yds of penalties on 54 infractions, ranking them 64th in Division 1 in terms of helping out the other team. They average 183.9 rushing yards per game and have toted the ball for 1,655 yards overall. They have tossed 6 interceptions while conceding 6 fumbles and they have been able to record 175 1st downs. In relation to their scoring prowess, the Mountaineers sit 100th in college football averaging 23.2 PPG. Over the course of the season to this point, the Mountaineers currently sit at 1,569 passing yards along with holding an average of 174.3 passing yards per game, which has them sitting 117th in the nation.

West Virginia has surrendered a total of 1,363 yards via the ground game (151.4 yards/game) as well as 13 touchdowns on the ground on the campaign. They have surrendered 18 touchdowns through the air and 255.0 yards/contest, which puts them in 115th in the country. Overall, they have surrendered 274 total points. They have tallied 6 fumbles recovered and 10 interceptions over the course of the season. The Mountaineers defense has taken the field for 635 plays, which has them ranked 128th in college football. The Mountaineers are surrendering 30.4 points per contest, which has them sitting 110th in Division 1.

Who will win tonight's Buffaloes/Mountaineers college football game against the spread?

Guy's Pick: Take the Buffaloes +6.5

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