Connecticut Huskies vs Buffalo Bulls Prediction, 9/27/2025 College Football Picks, Best Bets & Odds

Game: Connecticut Huskies vs Buffalo Bulls

Date: Saturday, September 27, 2025

Location: UB Stadium in Buffalo, NY

TV: ESPN+

Odds/Point Spread: Bulls (+2.5)

Total/Over-Under: 51

The Buffalo Bulls (2-2) welcome the Connecticut Huskies (2-2) at UB Stadium on Saturday, September 27, 2025. Connecticut opens as 2.5-point favorites. The over/under is 51.

The Connecticut Huskies come into this matchup with a record of 2-2 this season. In their last game, the Huskies faced off with the Ball State Cardinals and took home the win by a score of 31-25. When all was said and done, they ran 67 plays for 400 yds. The Connecticut Huskies ran the rock 37 times and compiled 219 yds, which is an average of 5.9 yards per attempt. On the ground, the Huskies gave up 176 yds on 37 tries, which is 4.8 yards per run surrendered. Connecticut surrendered 18 pass completions on 25 tries for a total of 228 yds, and a completion percentage of 72.0%.

The Huskies have racked up 1,975 total yards over the course of this year. When it comes to getting the ball in the endzone, Connecticut has earned 8 passing touchdowns and 11 rushing touchdowns. They have yet to turn the ball over. Connecticut has earned 92 1st downs, and they have been called for 21 infractions for 197 yards. As a team they are averaging 196.5 yards via the ground game ranking them 43rd in Division 1. When it comes to scoring, the Connecticut Huskies have an average of 37.8 PPG.

In terms of passing yardage, the Huskies have allowed 1,038 yds which has them ranked 115th in college football. They have conceded 259.5 yards per outing through the air and allowed a completion percentage of 61.8%. During this campaign, they have yielded 408.5 yards per game which ranks them 111th in D-1. They have surrendered 5 touchdowns through the air and 8 touchdowns on the ground. The opposition is running for 4.0 yards per rushing attempt and 149.0 rushing yards per game so far this season. In total, they have conceded 596 yards on the ground through 4 games. The Huskies are ranked 96th in the nation when it comes to the opposition scoring, allowing 27.3 points per contest.

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The Bulls head into this game 2-2 this season. When they last stepped on the field, the Bulls took a loss by a score of 21-17 against the Troy Trojans. Buffalo relinquished 47 rush attempts for 163 yds (3.5 yds per rush). The Bulls passing defense gave up a completion rate of 52.8%, relinquishing 202 yds on 19 out of 36 passing. The Bulls finished with 278 yds while running 62 plays (4.5 yards per play). Buffalo rushed for 3.7 yds per carry, finishing with 125 yds on 34 attempts.

The Buffalo Bulls are averaging 345.8 yards per game, which has them ranked 101st in the nation. The Buffalo offense has 146 yards of penalties on 16 violations, which is good for 111th in the country in terms of giving up free yards. They have an average of 168.0 yards per game via the rush and have run for 672 yards for the season. They have given away 3 picks while letting opponents recover 2 fumbles and they have obtained 77 first downs. Concerning how much they score, the Bulls currently sit 87th in college football holding an average of 25.8 PPG. Over the course of the season so far, the Bulls currently have a total of 711 yards via the pass in addition to holding an average of 177.8 throwing yards per outing, which ranks 112th in the country.

Buffalo has surrendered a total of 464 yards via the ground game (116.0 yards per contest) and 5 touchdowns rushing so far this season. They have allowed the opposition 5 touchdowns through the air and 221.5 yards/outing, which has them in 85th in the country. Overall, they have conceded 78 points. Their defense has 3 fumbles and 2 interceptions this season. The Bulls defense has participated in 291 plays, which ranks 124th in Division 1. The Bulls are surrendering 19.5 points per contest, which has them sitting 49th in the nation.

Who will win tonight's Huskies/Bulls college football game against the spread?

Josh's Pick: Take the Huskies -2.5

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