Connecticut Huskies vs Syracuse Orange Prediction, 9/6/2025 College Football Picks, Best Bets & Odds

Game: Connecticut Huskies vs Syracuse Orange

Date: Saturday, September 6, 2025

Location: JMA Wireless Dome in Syracuse, NY

TV: ESPN/ESPN+

Odds/Point Spread: Orange (-6.5)

Total/Over-Under: 58

The Connecticut Huskies (1-0) are headed to JMA Wireless Dome on Saturday, September 6, 2025 where they will attempt to defeat the Syracuse Orange (0-1). Connecticut opens this matchup as 6.5-point dogs. The over/under is 58.

The Connecticut Huskies head into this game 1-0 for this season. The last time they stepped onto the field, the Huskies faced off with the Central Connecticut State Blue Devils and took home the win by a score of 59-13. On the day, they ran 71 plays which gave them 638 yards. The Connecticut Huskies ran the ball a total of 33 different times and totaled 250 yards, which had them averaging 7.6 yds per carry. Against the run, the Huskies conceded 128 yards on 40 attempts, which averages out to 3.2 yards per run allowed. Connecticut conceded 9 pass completions on 23 attempts for a total of 129 yards, and a completion percentage of 39.1%.

The Huskies have earned 638 yards in total for this campaign. In terms of scoring, Connecticut has amassed 4 touchdowns via the pass and 4 touchdowns on the ground. They have yet to turn the ball over. Connecticut has recorded 26 first downs as a team, and they have been hurt by 8 penalties for 78 yds. As a team they hold an average of 250.0 yards on the ground which ranks them 23rd in the country. In terms of putting points on the board, the Connecticut Huskies are averaging 59.0 points per game.

The Huskies are sitting in 56th in Division 1 in terms of the opposition scoring, giving up 13.0 points per game. They are giving up an average of 3.2 yards per rushing attempt and 128.0 yards on the ground per game for the campaign. For the season, they have allowed 128 rushing yards through 1 outing. When it comes to yards through the air, the Huskies have allowed 129 yds which puts them in 33rd in college football. They are allowing 129.0 yards per contest through the air and conceding a completion percentage of 39.1%. In total, they have surrendered 257.0 yards/outing ranking them 45th in D-1. They have surrendered 1 touchdown pounding the rock.

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The Orange head into this matchup 0-1 this season. When they last played, the Orange went home defeated by a final of 45-26 when they played the Tennessee Volunteers. Syracuse ended up running for 2.3 yards per tote, finishing with 103 yards on 44 attempts. The Orange finished with 377 yds while they ran 84 plays (4.5 yards per play). The Orange pass defense allowed a completion percentage of 57.1%, relinquishing 247 yards on 16 for 28 passing. Syracuse allowed 40 attempts on the ground for 246 yds (6.2 yds per rush).

The Syracuse Orange average 377.0 yards per contest, which has them sitting 71st in Division 1. The Syracuse offense has 30 penalty yds on 4 violations, which ranks 106th in Division 1 in terms of helping out the other team. They average 103.0 rushing yards per game. They have been able to record 24 first downs. Regarding their ability to score points, the Orange are sitting 72nd in college football scoring 26.0 PPG. During the season thus far, the Orange have thrown for a total of 274 passing yards, which has them sitting 33rd in the nation.

Syracuse has surrendered a total of 246 rushing yards. They have allowed 3 touchdowns from the passing game as well as 247.0 yards/outing, which puts them in 102nd in the nation. They have caused 1 fumble this season. The Orange defense has taken part in 68 plays, which is good for 83rd in the country. The Orange are giving up 45.0 points per game, which has them sitting 129th in Division 1.

Who will win tonight's Huskies/Orange college football game against the spread?

Guy's Pick: Take the Huskies +6.5

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