Duke Blue Devils vs California Golden Bears Prediction, 10/4/2025 College Football Picks, Best Bets & Odds

Game: Duke Blue Devils vs California Golden Bears

Date: Saturday, October 4, 2025

Location: California Memorial Stadium in Berkeley, CA

TV: ESPN

Odds/Point Spread: Golden Bears (+2.5)

Total/Over-Under: 55.5

California Memorial Stadium is the site where the California Golden Bears (4-1) will meet the Duke Blue Devils (3-2) on Saturday, October 4, 2025. Duke opens as 2.5-point favorites. The total has been set at 55.5.

The Duke Blue Devils head into this game 3-2 this year. In their last contest, the Blue Devils took the field against the Syracuse Orange and walked away with a win by a score of 38-3. In all, they ran 65 plays which converted into 503 yards. The Duke Blue Devils ran the ball a total of 37 different times and compiled 235 yards, which is an average of 6.4 yds per attempt. In the running game, the Blue Devils gave up 85 yds on 27 tries, which is an average of 3.1 yards per rush surrendered. Duke allowed 24 pass completions on 37 tries for 229 yards, and a completion percentage of 64.9%.

In terms of putting the ball in the endzone, the Duke Blue Devils are averaging 34.8 points per contest. As a team they have an average of 152.8 yards via the ground game which ranks them 76th in D-1. The Blue Devils have tallied 2,359 total yards over the course of this year. With reference to getting the ball in the endzone, Duke has earned 13 passing touchdowns and 8 touchdowns on the ground. Duke has earned 116 1st downs, and they have been hurt by 35 infractions for 377 yds. They have given the ball to the opposition 7 different times.

The Blue Devils rank 87th in D-1 when it comes to the opposition scoring, allowing 26.4 PPG. The opposition is running for an average of 3.8 yards per attempt on the ground and 139.6 rushing yards per contest so far this year. In total, they have given up 698 yards via the ground game in 5 games. When talking about yards through the air, the Blue Devils have given up 1,271 yards which has them ranked 126th in the country. They have surrendered 254.2 yards per contest via the pass as well as allowing a completion percentage of 68.7%. During the season, they have relinquished 393.8 yards/outing which has them ranked 99th in the country. They have allowed 5 touchdowns via the pass as well as 12 touchdowns via the ground game.

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The Golden Bears step onto the field holding a record of 4-1 for this season. When they last played, the Golden Bears walked away with a victory by a final of 28-24 when they played the Boston College Eagles. California ran the ball for 3.2 yds per attempt, totaling 118 yards on 37 attempts. The Golden Bears finished with 372 yards while they ran 71 plays (5.2 yds per play). The Golden Bears pass defense allowed a completion percentage of 56.8%, relinquishing 197 yards on 21 out of 37 passing. California conceded 21 run attempts for 178 yds (8.5 yds per carry).

The California Golden Bears maintain an average of 364.8 yards/game, which has them sitting 89th in the nation. The California offense has accrued 297 penalty yds on 38 infractions, which ranks 17th in the country in terms of helping out the other team. They maintain an average of 107.8 rushing yards per game and have run for 539 yards for the year. They have tossed 4 interceptions while conceding 2 fumbles and they have been able to obtain 97 1st downs. Regarding how much they score, the Golden Bears are ranking 89th in the country by tallying 24.8 points per outing. During this campaign thus far, the Golden Bears have thrown for a total of 1,285 yards through the air in addition to holding an average of 257.0 throwing yards per contest, giving them a rank of 48th in D-1.

California has given up a total of 560 yards on the ground (112.0 yards/game) and 7 touchdowns by way of the ground game for the year. They have allowed 2 touchdowns through the air in addition to 195.2 yards per outing, ranking them 53rd in Division 1. Over the course of the season, they have conceded 90 pts. Their defense has totaled 2 fumbles and 5 interceptions on the campaign. The Golden Bears defense has been on the field for 299 plays, which has them sitting 75th in D-1. The Golden Bears are allowing 18.0 points per contest, which has them ranked 35th in the nation.

Who will win tonight's Blue Devils/Golden Bears college football game against the spread?

Josh's Pick: Take the Golden Bears +2.5

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