Florida State Seminoles vs Clemson Tigers Prediction, 11/8/2025 College Football Picks, Best Bets & Odds

Game: Florida State Seminoles vs Clemson Tigers

Date: Saturday, November 8, 2025

Location: Memorial Stadium in Clemson, SC

TV: ACC Network

Odds/Point Spread: Tigers (-2.0)

Total/Over-Under: 56

The Clemson Tigers (3-5) are hosting the Florida State Seminoles (3-4) at Memorial Stadium on Saturday, November 8, 2025. Clemson opens this contest as 2.0-point favorites. The total comes in at 56.

The Florida State Seminoles come into this game with a record of 3-4 for this season. In their last game, the Seminoles faced the Wake Forest Demon Deacons and walked away with a win by a score of 42-7. The Florida State Seminoles ran the ball a total of 40 different times and accumulated 150 yards, earning them an average of 3.8 yds per carry. For the game, they ran 57 plays which gave them a total of 421 yds. Florida State allowed 18 pass completions on 31 tries for 162 yds, and a completion rate of 58.1%. On the ground, the Seminoles conceded 85 yds on 40 attempts, which is an average of 2.1 yards per rush surrendered.

The Seminoles have earned 4,084 total yards this year. When it comes to distribution of touchdowns, Florida State has amassed 15 passing touchdowns and 27 touchdowns via the ground. They have turned the ball over 11 times. Florida State has recorded 200 first downs as an offense, and they have committed 47 infractions for 424 yards. As a unit they're maintaining an average of 241.3 yards rushing which is 8th in the country. When it comes to scoring points, the Florida State Seminoles have an average of 40.0 points per game.

The Seminoles rank 33rd in the country concerning team defense, allowing 20.6 points per contest. They are allowing an average of 3.1 yards per rushing attempt and 114.4 rushing yards per game on the year. During the season, they have allowed 915 running yards through 8 games. Concerning passing yardage, the Seminoles are giving up 1,623 yds which has them sitting in 28th in D-1. They have conceded 202.9 yards per game via the pass in addition to giving up a completion percentage of 60.6%. Over the course of this season, they are conceding 317.3 yards per outing ranking them 26th in the nation. They have given up 13 touchdowns via the pass in addition to 7 touchdowns pounding the rock.

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The Tigers head into this matchup 3-5 for this year. The last time they took the field, the Tigers took a loss by a final score of 46-45 against the Duke Blue Devils. Clemson relinquished 22 rushing attempts for 78 yards (3.5 yards per carry). The Tigers pass defense gave up a completion rate of 64.3%, surrendering 361 yards on 27 out of 42 passing. The Tigers finished the game with a total of 560 yards while running 72 plays (7.8 yds per play). Clemson rushed the football for 4.9 yards per tote, finishing with a total of 175 yards on 36 attempts.

The Clemson Tigers have an average of 420.6 yards/contest, which ranks them 41st in the country. The Clemson offense has accrued 396 penalty yds on 39 violations, which is good for 119th in the nation in terms of helping out the other team. They have an average of 123.8 yards via the ground game and have rushed for 990 yards in total. They have given away 6 picks while conceding 7 fumbles and they have been able to tally 175 1st downs. Concerning their scoring prowess, the Tigers rank 71st in Division 1 holding an average of 28.4 PPG. Over the course of the season so far, the Tigers have compiled 2,375 passing yards not to mention holding an average of 296.9 passing yards per game, which has them ranked 13th in Division 1.

The Tigers are surrendering 24.0 points per game, which has them sitting 67th in college football. Clemson has allowed the opposition a total of 846 yards via the ground game (105.8 yards per game) and 9 touchdowns by way of the ground game for the campaign. They have yielded 11 touchdowns from the passing game as well as 244.5 yards per game, ranking them 103rd in D-1. The Tigers defense has participated in 536 plays, which is good for 46th in college football. They have earned 3 fumbles recovered and 5 picks this season. Overall, they have surrendered 192 pts.

Who will win tonight's Seminoles/Tigers college football game against the spread?

Josh's Pick: Take the Tigers -2.0

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