Georgia Southern Eagles vs USC Trojans Prediction, 9/6/2025 College Football Picks, Best Bets & Odds
Game: Georgia Southern Eagles vs USC Trojans
Date: Saturday, September 6, 2025
Location: Los Angeles Memorial Coliseum in Los Angeles, CA
TV: FS1
Odds/Point Spread: Trojans (-29.0)
Total/Over-Under: 62
Los Angeles Memorial Coliseum is the location where the USC Trojans (1-0) will go up against the Georgia Southern Eagles (0-1) on Saturday, September 6, 2025. USC opens as 29.0-point favorites from oddsmakers. The total has been set at 62.
The Georgia Southern Eagles head into this game 0-1 for this season. The last time they took the field, the Eagles faced the Fresno State Bulldogs and went home with a loss by a final score of 42-14. When it came to stopping the run, the Eagles gave up 351 yards on 45 attempts, which is 7.8 yds per run allowed. Georgia Southern allowed 20 completions on 27 tries for a total of 176 yards, and a completion rate of 74.1%. When all was said and done, they had 49 plays which gave them 242 yards. The Georgia Southern Eagles ran the football 21 times and recorded 84 yds, which had them averaging 4.0 yds per carry.

The Eagles have attained 242 total yards for the year. When it comes to scoring touchdowns, Georgia Southern has totaled 2 touchdowns via the pass. They have given the ball to the opposition 1 time. Georgia Southern has earned 13 1st downs as a unit, and they have committed 5 infractions for 58 yds. As a team they're averaging 84.0 yards rushing which has them sitting 113th in the country. Concerning putting points on the board, the Georgia Southern Eagles hold an average of 14.0 PPG.
Concerning yards through the air, the Eagles have allowed 176 yards which ranks them 64th in the nation. They have allowed 176.0 yards per game through the air as well as allowing a completion percentage of 74.1%. Over the course of this season, they are conceding 527.0 yards/outing which ranks them 131st in the nation. They have granted 5 touchdowns running the ball. The opposition is running for 7.8 yards per run and 351.0 yards on the ground per game so far this year. For the season, they have conceded 351 yards on the ground through 1 contest. The Eagles are sitting in 127th in the country regarding the opposition scoring, conceding 42.0 PPG.
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The Trojans head into this matchup 1-0 this year. In their last game, the Trojans took home the win by a final score of 73-13 against the Missouri State Bears. The Trojans finished with a total of 597 yds while running 57 plays (10.5 yards per play). USC rushed for 7.8 yds per attempt, finishing with a total of 233 yds on 30 attempts. USC surrendered 29 rush attempts for 65 yds (2.2 yards per rush). The Trojans pass defense conceded a completion percentage of 71.4%, relinquishing 159 yds on 20 for 28 passing.
The USC Trojans hold an average of 597.0 yards per outing, ranking them 7th in the nation. The USC offense has racked up 45 penalty yds on 5 violations, which ranks 77th in college football in terms of hurting your team. They are averaging 233.0 rushing yards per game. They have recorded 27 1st downs. When it comes to the points being put on the board, the Trojans are 1st in college football by scoring 73.0 points per outing. During the season thus far, the Trojans have compiled 364 yards through the air, which ranks 10th in the country.
USC has yielded a total of 65 yards on the ground. They have given up 1 touchdown via the pass as well as 159.0 yards/contest, ranking them 55th in the nation. Their defense has 1 fumble and 2 picks for the year. The Trojans defense has taken the field for 57 plays, which is good for 32nd in college football. The Trojans are conceding 13.0 points per contest, which has them sitting 53rd in the country.
Who will win tonight's Eagles/Trojans college football game against the spread?
Josh's Pick: Take the Eagles +29.0
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Additional Resources:
USC Trojans - Twitter
Georgia Southern Eagles - Twitter