Iowa State Cyclones vs TCU Horned Frogs Prediction, 11/8/2025 College Football Picks, Best Bets & Odds

Game: Iowa State Cyclones vs TCU Horned Frogs

Date: Saturday, November 8, 2025

Location: Amon G. Carter Stadium in Fort Worth, TX

TV: FOX

Odds/Point Spread: Horned Frogs (-6.5)

Total/Over-Under: 58

Amon G. Carter Stadium is the site where the TCU Horned Frogs (6-2) will play the Iowa State Cyclones (5-4) on Saturday, November 8, 2025. TCU opens this game as 6.5-point favorites. The total is 58.

The Iowa State Cyclones come into this game with a record of 5-4 this year. The last time they stepped onto the field, the Cyclones played against the Arizona State Sun Devils and ended up losing by a score of 24-19. The Iowa State Cyclones ran the football 32 different times and amassed 150 yards, which is an average of 4.7 yds per carry. Once the final whistle blew, they ran 69 plays which totaled 336 yds. Iowa State relinquished 13 pass completions on 24 tries for a total of 177 yds, and a completion rate of 54.2%. Against the run, the Cyclones gave up 290 yards on 46 attempts, which is 6.3 yds per rush allowed.

When it comes to putting points on the board, the Iowa State Cyclones hold an average of 27.9 PPG. As a unit they average 164.6 yards on the ground which is 58th in the nation. The Cyclones have earned 3,673 total yards this season. In terms of getting in the endzone, Iowa State has earned 11 passing touchdowns and 19 touchdowns via the ground. Iowa State has accounted for 196 first downs offensively, and they have been called for 40 infractions for 327 yds. They have given the ball to the opposition 11 different times.

The Cyclones are sitting in 47th in the nation regarding team defense, conceding 22.0 points per game. The opposition is running for 4.6 yards per rush and 153.8 rushing yards per game for the campaign. During the season, they have allowed 1,384 yards on the ground through 9 games. When it comes to passing yardage, the Cyclones have allowed 1,910 yds which ranks them 78th in D-1. They are allowing 212.2 yards per outing through the air as well as allowing a completion percentage of 59.9%. For the year, they have relinquished 366.0 yards per game ranking them 63rd in college football. They have given up 12 touchdowns by air in addition to 11 touchdowns on the ground.

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The Horned Frogs step onto the field holding a record of 6-2 this season. When they last stepped on the field, the Horned Frogs went home victorious with a score of 23-17 against the West Virginia Mountaineers. TCU conceded 32 rushing attempts for 41 yards (1.3 yards per carry). The Horned Frogs pass defense allowed a completion rate of 68.3%, relinquishing 301 yards on 28 out of 41 through the air. The Horned Frogs finished the game with a total of 343 yards while running 72 plays (4.8 yds per play). TCU rushed the football for 2.9 yds per attempt, finishing with 96 yards on 33 attempts.

In relation to how much they score, the Horned Frogs are sitting 29th in the country with an average of 34.6 points per outing. The TCU Horned Frogs average 425.5 yards per game, which is good for 40th in Division 1. The TCU offense has racked up 520 yds of penalties on 54 violations, which is 55th in D-1 in terms of helping out the opposition. They have thrown 7 picks while losing 3 fumbles and they have been able to earn 174 1st downs. Over the course of the season so far, the Horned Frogs have racked up 2,412 yards through the air along with holding an average of 301.5 passing yards per outing, ranking them 11th in the country. They maintain an average of 124.0 run yards per game and have run for 992 yards for the season.

The Horned Frogs are allowing 25.1 points per game, which puts them 75th in D-1. TCU has surrendered a total of 955 yards rushing (119.4 yards per contest) in addition to 5 touchdowns via the rush this year. They have surrendered 17 touchdowns via the pass as well as 257.9 yards/game, which has them ranked 118th in D-1. The Horned Frogs defense has taken part in 570 plays, which ranks them 71st in Division 1. Their defense has compiled 5 fumbles and 9 interceptions this season. In total, they have allowed 201 points in total.

Who will win tonight's Cyclones/Horned Frogs college football game against the spread?

Tony's Pick: Take the Cyclones +6.5

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