Louisiana Tech Bulldogs vs LSU Tigers Prediction, 9/6/2025 College Football Picks, Best Bets & Odds
Game: Louisiana Tech Bulldogs vs LSU Tigers
Date: Saturday, September 6, 2025
Location: Tiger Stadium in Baton Rouge, LA
TV: ESPN/ESPN+
Odds/Point Spread: Tigers (-37.5)
Total/Over-Under: 51
The LSU Tigers (1-0) will try to beat the Louisiana Tech Bulldogs (1-0) at Tiger Stadium on Saturday, September 6, 2025. Louisiana Tech opens as 37.5-point dogs from oddsmakers. The over/under comes in at 51.
The Louisiana Tech Bulldogs come into this matchup with a record of 1-0 for this year. The last time they took the field, the Bulldogs faced the Southeastern Louisiana Lions and earned the victory with a final of 24-0. Once the final whistle blew, they tallied 53 plays for 262 yards. The Louisiana Tech Bulldogs rushed the ball a total of 34 times and totaled 136 yards, which earned them an average of 4.0 yards per tote. When it came to stopping the run, the Bulldogs gave up 126 yards on 44 tries, which averages out to 2.9 yards per rush allowed. Louisiana Tech conceded 15 completions on 31 attempts for 145 yds, and a completion percentage of 48.4%.

The Bulldogs have tallied 262 yards in total this season. With reference to notching touchdowns, Louisiana Tech has earned 1 touchdown through the air and 1 touchdown on the ground. They haven't turned the ball over yet. Louisiana Tech has accounted for 14 1st downs as an offense, and they have committed 5 infractions for 50 yards. As a unit they're holding an average of 136.0 yards on the ground which is 79th in college football. Regarding scoring points, the Louisiana Tech Bulldogs have an average of 24.0 points per outing.
Concerning passing yards, the Bulldogs have given up 145 yards which ranks them 42nd in college football. They have allowed 145.0 yards per game through the air and giving up a completion percentage of 48.4%. For the season, they have surrendered 271.0 yards/contest putting them at 52nd in the nation. They have yet to surrender a touchdown on defense. They are allowing 2.9 yards per rushing attempt and 126.0 rushing yards per game for the year. Over the course of this year, they have conceded 126 running yards through 1 game. The Bulldogs rank 7th in the nation concerning their opponents scoring, giving up 0.0 PPG.
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The Tigers come into this game with a record of 1-0 for this year. For their last game, the Tigers went home victorious with a score of 17-10 when they played the Clemson Tigers. LSU allowed 20 run attempts for 31 yards (1.6 yds per rush). The Tigers secondary allowed a completion rate of 50.0%, relinquishing 230 yards on 19 for 38 through the air. The Tigers ended up finishing with 356 yds on 70 plays (5.1 yards per play). LSU ran the ball for 3.5 yards per carry, finishing with a total of 108 yards on 31 attempts.
The LSU Tigers are averaging 356.0 yards per game, which ranks them 81st in Division 1. The LSU offense has racked up 45 penalty yds on 6 infractions, which ranks 71st in D-1 in terms of helping out the other team. They maintain an average of 108.0 rushing yards per game. They have earned 25 first downs. When discussing the points being put on the board, the Tigers are ranking 95th in the nation averaging 17.0 points per contest. During this campaign so far, the Tigers have racked up 248 passing yards, which has them sitting 49th in the country.
LSU has surrendered a total of 31 yards on the ground. They have given up 230.0 passing yards per outing, which puts them in 94th in the country. Their defense has 1 pick on the campaign. The Tigers defense has taken the field for 58 plays, which is good for 37th in Division 1. The Tigers are relinquishing 10.0 points per game, which has them sitting 44th in college football.
Who will win tonight's Bulldogs/Tigers college football game against the spread?
Josh's Pick: Take the Bulldogs +37.5
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Additional Resources:
LSU Tigers - Twitter
Louisiana Tech Bulldogs - Twitter