Michigan State Spartans vs Nebraska Cornhuskers Prediction, 10/4/2025 College Football Picks, Best Bets & Odds

Game: Michigan State Spartans vs Nebraska Cornhuskers

Date: Saturday, October 4, 2025

Location: Memorial Stadium in Lincoln, NE

TV: FS1

Odds/Point Spread: Cornhuskers (-11.0)

Total/Over-Under: 53

Memorial Stadium is the site where the Nebraska Cornhuskers (3-1) will meet the Michigan State Spartans (3-1) on Saturday, October 4, 2025. Michigan State opens this matchup as 11.0-point underdogs. The over/under is set at 53.

The Michigan State Spartans come into this matchup with a record of 3-1 for this season. The last time they took the field, the Spartans played against the USC Trojans and went home with a loss by a final score of 45-31. The Michigan State Spartans ran the rock 32 times and compiled 112 yds, which earned them an average of 3.5 yards per carry. Overall, they had 55 plays which gave them a total of 337 yds. Michigan State surrendered 20 pass completions on 26 attempts for 234 yards, and a completion rate of 76.9%. Against the run, the Spartans conceded 289 yds on 40 attempts, which averages out to 7.2 yards per rush allowed.

The Spartans have earned 1,497 yards in total for the year. When it comes to notching touchdowns, Michigan State has compiled 9 touchdowns via the pass and 8 touchdowns via the ground. They have given the ball to the opposition 4 times. Michigan State has amassed 84 1st downs, and they have committed 19 penalties for 158 yards. As a unit they hold an average of 154.0 yards in the run game which has them sitting 72nd in the nation. When it comes to putting points on the board, the Michigan State Spartans are averaging 34.3 points per game.

Regarding yards via the pass, the Spartans are giving up 1,054 yds which has them sitting in 87th in the country. They have surrendered 263.5 yards per contest via the pass in addition to conceding a completion percentage of 67.5%. In total, they have allowed 384.0 yards per outing ranking them 91st in D-1. They have yielded 9 touchdowns via the pass and 5 touchdowns pounding the rock. The opposition is running for an average of 4.2 yards per run and 120.5 yards on the ground per game for the campaign. During this campaign, they have conceded 482 yards on the ground through 4 contests. The Spartans rank 106th in the nation in terms of team defense, conceding 28.8 points per game.

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The Cornhuskers head into this game 3-1 for this season. When they last stepped on the gridiron, the Cornhuskers took a loss by a score of 30-27 when they played the Michigan Wolverines. Nebraska ended up running for 1.4 yds per carry, totaling 43 yds on 31 carries. The Cornhuskers finished the contest with a total of 351 yds while running 72 plays (4.9 yards per play). The Cornhuskers passing defense gave up a completion rate of 52.2%, relinquishing 105 yards on 12 out of 23 through the air. Nebraska allowed 33 rushing attempts for 286 yards (8.7 yards per rush).

In terms of this team's ability to score points, the Cornhuskers are sitting 12th in the nation by scoring 43.5 points per outing. The Nebraska Cornhuskers average 496.5 yards per outing, which has them ranked 13th in D-1. The Nebraska offense has 152 yards of penalties on 16 infractions, which has them ranked 126th in college football in terms of making mistakes. They have thrown 1 pick while letting opponents recover 1 fumble and they have been able to tally 107 first downs. During the season so far, the Cornhuskers have thrown for 1,407 passing yards along with an average of 351.8 passing yards per game, which has them ranked 2nd in the nation. They are averaging 144.8 yards per game on the ground and have run for 579 yards overall.

Nebraska has allowed the opposition a total of 694 yards via the ground game (173.5 yards/game) as well as 6 touchdowns on the ground so far this year. They have allowed 0 touchdowns through the air and 75.8 yards per outing, which has them sitting 1st in the country. This season, they have allowed 54 total points. Their defense has totaled 5 fumbles recovered and 1 interception this year. The Cornhuskers defense has taken the field for 223 plays, ranking them 4th in Division 1. The Cornhuskers are surrendering 13.5 points per game, which puts them 16th in Division 1.

Who will win tonight's Spartans/Cornhuskers college football game against the spread?

Josh's Pick: Take the Spartans +11.0

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